| An inducible autoregulatory loop between HIPK2 and Siah2 at the apex of the hypoxic response MA Calzado, L De La Vega, A Möller, DDL Bowtell, ML Schmitz Nature cell biology 11 (1), 85-91, 2009 | 187 | 2009 |
| Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1 L Casares, V García, M Garrido-Rodríguez, E Millán, JA Collado, ... Redox Biology 28, 101321, 2020 | 141 | 2020 |
| A redox-regulated SUMO/acetylation switch of HIPK2 controls the survival threshold to oxidative stress L de la Vega, I Grishina, R Moreno, M Krüger, T Braun, ML Schmitz Molecular cell 46 (4), 472-483, 2012 | 115 | 2012 |
| The 5-HT3 receptor antagonist tropisetron inhibits T cell activation by targeting the calcineurin pathway L de la Vega, E Muñoz, MA Calzado, K Lieb, E Candelario-Jalil, ... Biochemical pharmacology 70 (3), 369-380, 2005 | 96 | 2005 |
| Crosstalk between NRF2 and HIPK2 shapes cytoprotective responses L Torrente, C Sanchez, R Moreno, S Chowdhry, P Cabello, K Isono, ... Oncogene 36 (44), 6204-6212, 2017 | 87 | 2017 |
| Heat shock factor 1 is a substrate for p38 mitogen-activated protein kinases S Dayalan Naidu, C Sutherland, Y Zhang, A Risco, L de la Vega, ... Molecular and cellular biology 36 (18), 2403-2417, 2016 | 81 | 2016 |
| Immunosuppressive activity of endovanilloids: N-arachidonoyl-dopamine inhibits activation of the NF-κB, NFAT, and activator protein 1 signaling pathways R Sancho, A Macho, L de La Vega, MA Calzado, BL Fiebich, ... The Journal of Immunology 172 (4), 2341-2351, 2004 | 81 | 2004 |
| HIPK2 kinase activity depends on cis-autophosphorylation of its activation loop VV Saul, L de la Vega, M Milanovic, M Krüger, T Braun, K Fritz-Wolf, ... Journal of molecular cell biology 5 (1), 27-38, 2013 | 70 | 2013 |
| Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism F Chen, WAM Elgaher, M Winterhoff, K Büssow, FH Waqas, E Graner, ... Nature Metabolism 4 (5), 534-546, 2022 | 56 | 2022 |
| Control of nuclear HIPK2 localization and function by a SUMO interaction motif L de la Vega, K Fröbius, R Moreno, MA Calzado, H Geng, ML Schmitz Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (2), 283-297, 2011 | 50 | 2011 |
| Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression S Banerjee, T Wei, J Wang, JJ Lee, HL Gutierrez, O Chapman, SE Wiley, ... Proceedings of the National Academy of Sciences 116 (49), 24881-24891, 2019 | 46 | 2019 |
| Emerging roles of DYRK2 in cancer V Tandon, L de la Vega, S Banerjee Journal of Biological Chemistry 296, 2021 | 44 | 2021 |
| Transcription factors NRF2 and HSF1 have opposing functions in autophagy S Dayalan Naidu, D Dikovskaya, E Gaurilcikaite, EV Knatko, ZR Healy, ... Scientific reports 7 (1), 11023, 2017 | 36 | 2017 |
| Mechanisms of HIV-1 inhibition by the lipid mediator N-arachidonoyldopamine R Sancho, L De La Vega, A Macho, G Appendino, V Di Marzo, E Muñoz The Journal of Immunology 175 (6), 3990-3999, 2005 | 35 | 2005 |
| Homeodomain-interacting protein kinase 2-dependent repression of myogenic differentiation is relieved by its caspase-mediated cleavage L De La Vega, J Hornung, E Kremmer, M Milanovic, ML Schmitz Nucleic acids research 41 (11), 5731-5745, 2013 | 30 | 2013 |
| The CB1/VR1 agonist arvanil induces apoptosis through an FADD/caspase‐8‐dependent pathway R Sancho, L De La Vega, G Appendino, V Di Marzo, A Macho, E Muñoz British journal of pharmacology 140 (6), 1035-1044, 2003 | 30 | 2003 |
| High NRF2 levels correlate with poor prognosis in colorectal cancer patients and with sensitivity to the kinase inhibitor AT9283 in vitro L Torrente, G Maan, A Oumkaltoum Rezig, J Quinn, A Jackson, A Grilli, ... Biomolecules 10 (10), 1365, 2020 | 28 | 2020 |
| The isothiocyanate sulforaphane inhibits mTOR in an NRF2-independent manner Y Zhang, A Gilmour, YH Ahn, L de la Vega, AT Dinkova-Kostova Phytomedicine 86, 153062, 2021 | 27 | 2021 |
| From top to bottom: the two faces of HIPK2 for regulation of the hypoxic response MA Calzado, L De La Vega, E Munoz, ML Schmitz Cell Cycle 8 (11), 1659-1664, 2009 | 26 | 2009 |
| Isomeric O-methyl cannabidiolquinones with dual BACH1/NRF2 activity L Casares, JD Unciti-Broceta, ME Prados, D Caprioglio, D Mattoteia, ... Redox Biology 37, 101689, 2020 | 24 | 2020 |
