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Jack Heal
Jack Heal
Cancer Research UK
Verified email at cruk.manchester.ac.uk
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Cited by
Year
De novo protein design: how do we expand into the universe of possible protein structures?
DN Woolfson, GJ Bartlett, AJ Burton, JW Heal, A Niitsu, AR Thomson, ...
Current opinion in structural biology 33, 16-26, 2015
2012015
ISAMBARD: an open-source computational environment for biomolecular analysis, modelling and design
CW Wood, JW Heal, AR Thomson, GJ Bartlett, AÁ Ibarra, RL Brady, ...
Bioinformatics 33 (19), 3043-3050, 2017
432017
Engineering protein stability with atomic precision in a monomeric miniprotein
EG Baker, C Williams, KL Hudson, GJ Bartlett, JW Heal, KL Porter Goff, ...
Nature chemical biology 13 (7), 764-770, 2017
372017
Inhibition of HIV-1 protease: the rigidity perspective
JW Heal, JE Jimenez-Roldan, SA Wells, RB Freedman, RA Römer
Bioinformatics 28 (3), 350-357, 2012
342012
‘Something in the way she moves’: The functional significance of flexibility in the multiple roles of protein disulfide isomerase (PDI)
RB Freedman, JL Desmond, LJ Byrne, JW Heal, MJ Howard, N Sanghera, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1865 (11), 1383-1394, 2017
292017
Does deamidation cause protein unfolding? A top‐down tandem mass spectrometry study
AJ Soulby, JW Heal, MP Barrow, RA Roemer, PB O'Connor
Protein Science 24 (5), 850-860, 2015
262015
Membrane-spanning α-helical barrels as tractable protein-design targets
A Niitsu, JW Heal, K Fauland, AR Thomson, DN Woolfson
Philosophical Transactions of the Royal Society B: Biological Sciences 372 …, 2017
232017
Applying graph theory to protein structures: an Atlas of coiled coils
JW Heal, GJ Bartlett, CW Wood, AR Thomson, DN Woolfson
Bioinformatics 34 (19), 3316-3323, 2018
122018
Rigidity analysis of HIV-1 protease
JW Heal, SA Wells, E Jimenez-Roldan, RF Freedman, RA Römer
Journal of Physics: Conference Series 286 (1), 012006, 2011
72011
Characterization of folding cores in the cyclophilin A-cyclosporin A complex
JW Heal, SA Wells, CA Blindauer, RB Freedman, RA Römer
Biophysical journal 108 (7), 1739-1746, 2015
52015
Effects of ligand binding on the rigidity and mobility of proteins: a computational and experimental approach
JW Heal
University of Warwick, 2013
32013
ORIGINAL PAPERS Genome analysis Application of the cghRA framework to the genomic characterization of Diffuse Large B-Cell Lymphoma S. Mareschal, P. Ruminy, M. Alcantara, C …
CW Wood, JW Heal, AR Thomson, GJ Bartlett, AA Ibarra, RL Brady, ...
BIOINFORMATICS 33 (19), 2017
2017
Effects of Ligand Binding on the Rigidity and Mobility of Proteins: An Experimental and Computational Approach
J Heal, C Blindauer, RB Freedman, R Roemer
Biophysical Journal 106 (2), 658a, 2014
2014
Experimental and Computational Studies on the Dynamics and Flexibility of Protein Disulfide-Isomerase (PDI)
RB Freedman, J Blood, D Clarke, J Heal, E Jimenez-Roldan, R Roemer, ...
Biophysical Journal 106 (2), 246a, 2014
2014
The effects of ligand binding on protein structure and rigidity: studies with HIV-1 protease and cyclophilin A
JW Heal, E Jimenez-Roldan, S Wells, R Freedman, R Roemer
FEBS JOURNAL 279, 472-472, 2012
2012
Characterizing the folding core of the cyclophilin A—cyclosporin A complex I: hydrogen exchange data and rigidity analysis
JW Heal, RA Römer, CA Blindauer, RB Freedman
(2017). Membrane-spanning-helical barrels as tractable protein-design targets. Philosophical Transactions B: Biological Sciences, 372 (1726),[20160213]. https://doi. org/10 …
A Niitsu, JW Heal, K Fauland, AR Thomson, DN Woolfson
Characterizing the folding core of the cyclophilin A—cyclosporin A complex II: improving folding core predictions by including mobility
JW Heal, SA Wells, RB Freedman, RA Römer
246a Monday, February 17, 2014
RB Freedman, J Blood, D Clarke, J Heal, E Jimenez-Roldan, R Roemer, ...
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