| Interaction hot spots for phase separation revealed by NMR studies of a CAPRIN1 condensed phase TH Kim, BJ Payliss, ML Nosella, ITW Lee, Y Toyama, JD Forman-Kay, ... Proceedings of the National Academy of Sciences 118 (23), e2104897118, 2021 | 53 | 2021 |
| Structural mechanism underlying G protein family-specific regulation of G protein-gated inwardly rectifying potassium channel H Kano, Y Toyama, S Imai, Y Iwahashi, Y Mase, M Yokogawa, M Osawa, ... Nature communications 10 (1), 2008, 2019 | 51 | 2019 |
| Dynamic regulation of GDP binding to G proteins revealed by magnetic field-dependent NMR relaxation analyses Y Toyama, H Kano, Y Mase, M Yokogawa, M Osawa, I Shimada Nature communications 8 (1), 1-15, 2017 | 34 | 2017 |
| Oligomeric assembly regulating mitochondrial HtrA2 function as examined by methyl-TROSY NMR Y Toyama, RW Harkness, TYT Lee, JT Maynes, LE Kay Proceedings of the National Academy of Sciences 118 (11), e2025022118, 2021 | 32 | 2021 |
| NMR method for characterizing microsecond-to-millisecond chemical exchanges utilizing differential multiple-quantum relaxation in high molecular weight proteins Y Toyama, M Osawa, M Yokogawa, I Shimada Journal of the American Chemical Society 138 (7), 2302-2311, 2016 | 32 | 2016 |
| Mapping the per-residue surface electrostatic potential of CAPRIN1 along its phase-separation trajectory Y Toyama, AK Rangadurai, JD Forman-Kay, LE Kay Proceedings of the National Academy of Sciences 119 (36), e2210492119, 2022 | 23 | 2022 |
| Conformational landscape alternations promote oncogenic activities of Ras-related C3 botulinum toxin substrate 1 as revealed by NMR Y Toyama, K Kontani, T Katada, I Shimada Science advances 5 (3), eaav8945, 2019 | 23 | 2019 |
| Structural basis for the ethanol action on G-protein–activated inwardly rectifying potassium channel 1 revealed by NMR spectroscopy Y Toyama, H Kano, Y Mase, M Yokogawa, M Osawa, I Shimada Proceedings of the National Academy of Sciences 115 (15), 3858-3863, 2018 | 16 | 2018 |
| The A39G FF domain folds on a volcano-shaped free energy surface via separate pathways VP Tiwari, Y Toyama, D De, LE Kay, P Vallurupalli Proceedings of the National Academy of Sciences 118 (46), e2115113118, 2021 | 14 | 2021 |
| Competing stress-dependent oligomerization pathways regulate self-assembly of the periplasmic protease-chaperone DegP RW Harkness, Y Toyama, ZA Ripstein, H Zhao, AIM Sever, Q Luan, ... Proceedings of the National Academy of Sciences 118 (32), e2109732118, 2021 | 13 | 2021 |
| Dissecting the role of interprotomer cooperativity in the activation of oligomeric high-temperature requirement A2 protein Y Toyama, RW Harkness, LE Kay Proceedings of the National Academy of Sciences 118 (35), e2111257118, 2021 | 12 | 2021 |
| Surface electrostatics dictate RNA-binding protein CAPRIN1 condensate concentration and hydrodynamic properties Y Toyama, AK Rangadurai, JD Forman-Kay, LE Kay Journal of Biological Chemistry 299 (1), 2023 | 9 | 2023 |
| Measurement of 1Hα transverse relaxation rates in proteins: application to solvent PREs Y Toyama, AK Rangadurai, LE Kay Journal of Biomolecular NMR 76 (4), 137-152, 2022 | 9 | 2022 |
| Less is more: A simple methyl-TROSY based pulse scheme offers improved sensitivity in applications to high molecular weight complexes N Bolik-Coulon, AIM Sever, RW Harkness, JM Aramini, Y Toyama, ... Journal of Magnetic Resonance 346, 107326, 2023 | 8 | 2023 |
| Probing allosteric interactions in homo-oligomeric molecular machines using solution NMR spectroscopy Y Toyama, LE Kay Proceedings of the National Academy of Sciences 118 (50), e2116325118, 2021 | 8 | 2021 |
| Structural basis of protein substrate processing by human mitochondrial high-temperature requirement A2 protease Y Toyama, RW Harkness, LE Kay Proceedings of the National Academy of Sciences 119 (17), e2203172119, 2022 | 7 | 2022 |
| Analyzing multi-step ligand binding reactions for oligomeric proteins by NMR: Theoretical and computational considerations RW Harkness, Y Toyama, LE Kay Journal of Magnetic Resonance 318, 106802, 2020 | 6 | 2020 |
| Decreased conformational stability in the oncogenic N92I mutant of Ras-related C3 botulinum toxin substrate 1 Y Toyama, K Kontani, T Katada, I Shimada Science Advances 5 (8), eaax1595, 2019 | 5 | 2019 |
| Frequency selective coherence transfer NMR spectroscopy to study the structural dynamics of high molecular weight proteins Y Toyama, I Shimada Journal of Magnetic Resonance 304, 62-77, 2019 | 5 | 2019 |
| Practical considerations for the measurement of near-surface electrostatics based on solvent paramagnetic relaxation enhancements AK Rangadurai, Y Toyama, LE Kay Journal of Magnetic Resonance 349, 107400, 2023 | 3 | 2023 |
Lewis E KayUniversity of TorontoVerified email at pound.med.utoronto.ca
