| Differential downregulation of ACE2 by the spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus NL63 I Glowacka, S Bertram, P Herzog, S Pfefferle, I Steffen, MO Muench, ... Journal of virology 84 (2), 1198-1205, 2010 | 536 | 2010 |
| Mixture-based synthetic combinatorial libraries RA Houghten, C Pinilla, JR Appel, SE Blondelle, CT Dooley, J Eichler, ... Journal of medicinal chemistry 42 (19), 3743-3778, 1999 | 306 | 1999 |
| ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome MJ Taussig, O Stoevesandt, CAK Borrebaeck, AR Bradbury, D Cahill, ... Nature methods 4 (1), 13-17, 2007 | 257 | 2007 |
| Synthetic peptides as protein mimics A Groß, C Hashimoto, H Sticht, J Eichler Frontiers in bioengineering and biotechnology 3, 211, 2016 | 172 | 2016 |
| Identification of substrate-analog trypsin inhibitors through the screening of synthetic peptide combinatorial libraries J Eichler, RA Houghten Biochemistry 32 (41), 11035-11041, 1993 | 153 | 1993 |
| A review of the utility of soluble peptide combinatorial libraries C Pinilla, J Appel, S Blondelle, C Dooley, B Dörner, J Eichler, J Ostresh, ... Biopolymers: Original Research on Biomolecules 37 (3), 221-240, 1995 | 138 | 1995 |
| Combinatorial chemistry: a practical approach H Fenniri OUP Oxford, 2000 | 117 | 2000 |
| Cyclic peptide template combinatorial libraries: synthesis and identification of chymotrypsin inhibitors. J Eichler, AW Lucka, RA Houghten Peptide Research 7 (6), 300-307, 1994 | 110 | 1994 |
| Evaluation of cotton as a carrier for solid-phase peptide synthesis. J Eichler, M Bienert, A Stierandova, M Lebl Peptide Research 4 (5), 296-307, 1991 | 109 | 1991 |
| Peptide ligation through click chemistry for the generation of assembled and scaffolded peptides R Franke, C Doll, J Eichler Tetrahedron Letters 46 (26), 4479-4482, 2005 | 104 | 2005 |
| Versatility of positional scanning synthetic combinatorial libraries for the identification of individual compounds C Pinilla, JR Appel, SE Blondelle, CT Dooley, J Eichler, JM Ostresh, ... Drug development research 33 (2), 133-145, 1994 | 90 | 1994 |
| Forced dimerization of gp130 leads to constitutive STAT3 activation, cytokine-independent growth, and blockade of differentiation of embryonic stem cells C Stuhlmann-Laeisz, S Lang, A Chalaris, P Krzysztof, S Enge, J Eichler, ... Molecular biology of the cell 17 (7), 2986-2995, 2006 | 87 | 2006 |
| A monosaccharide residue is sufficient to maintain mouse and human IgG subclass activity and directs IgG effector functions to cellular Fc receptors D Kao, H Danzer, M Collin, A Groß, J Eichler, J Stambuk, G Lauc, A Lux, ... Cell reports 13 (11), 2376-2385, 2015 | 84 | 2015 |
| Peptides as protein binding site mimetics J Eichler Current opinion in chemical biology 12 (6), 707-713, 2008 | 81 | 2008 |
| Novel α-glucosidase inhibitors identified using multiple cyclic peptide combinatorial libraries J Eichler, AW Lucka, C Pinilla, RA Houghten Molecular diversity 1, 233-240, 1996 | 57 | 1996 |
| Application of cellulose paper as support material in simultaneous solid phase peptide synthesis J Eichler, M Beyermann, M Bienert Collection of Czechoslovak chemical communications 54 (6), 1746-1752, 1989 | 57 | 1989 |
| Combinatorial libraries: synthesis, screening and application potential R Cortese Walter de Gruyter, 2013 | 54 | 2013 |
| Method of performing multiple synthesis of peptides on solid carrier M Lebl, J Eichler, V Pokorny, J Jehnicka, P Mudra, K Zenisek, ... US Patent 5,202,418, 1993 | 53 | 1993 |
| Interference with ERK-dimerization at the nucleocytosolic interface targets pathological ERK1/2 signaling without cardiotoxic side-effects A Tomasovic, T Brand, C Schanbacher, S Kramer, MW Hümmert, P Godoy, ... Nature Communications 11 (1), 1733, 2020 | 47 | 2020 |
| Abrogation of viral interleukin-6 (vIL-6)-induced signaling by intracellular retention and neutralization of vIL-6 with an anti-vIL-6 single-chain antibody selected by phage … M Kovaleva, I Bussmeyer, B Rabe, J Grötzinger, E Sudarman, J Eichler, ... Journal of virology 80 (17), 8510-8520, 2006 | 47 | 2006 |
