Differential downregulation of ACE2 by the spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus NL63 I Glowacka, S Bertram, P Herzog, S Pfefferle, I Steffen, MO Muench, ... Journal of virology 84 (2), 1198-1205, 2010 | 482 | 2010 |
Mixture-based synthetic combinatorial libraries RA Houghten, C Pinilla, JR Appel, SE Blondelle, CT Dooley, J Eichler, ... Journal of medicinal chemistry 42 (19), 3743-3778, 1999 | 294 | 1999 |
ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome MJ Taussig, O Stoevesandt, CAK Borrebaeck, AR Bradbury, D Cahill, ... Nature Methods 4 (1), 13-17, 2007 | 254 | 2007 |
Identification of substrate-analog trypsin inhibitors through the screening of synthetic peptide combinatorial libraries J Eichler, RA Houghten Biochemistry 32 (41), 11035-11041, 1993 | 156 | 1993 |
Synthetic peptides as protein mimics A Groß, C Hashimoto, H Sticht, J Eichler Frontiers in bioengineering and biotechnology 3, 211, 2016 | 153 | 2016 |
A review of the utility of soluble peptide combinatorial libraries C Pinilla, J Appel, S Blondelle, C Dooley, B Dörner, J Eichler, J Ostresh, ... Biopolymers: Original Research on Biomolecules 37 (3), 221-240, 1995 | 134 | 1995 |
Combinatorial chemistry: a practical approach H Fenniri OUP Oxford, 2000 | 122 | 2000 |
Cyclic peptide template combinatorial libraries: synthesis and identification of chymotrypsin inhibitors. J Eichler, AW Lucka, RA Houghten Peptide Research 7 (6), 300-307, 1994 | 111 | 1994 |
Evaluation of cotton as a carrier for solid-phase peptide synthesis. J Eichler, M Bienert, A Stierandova, M Lebl Peptide Research 4 (5), 296-307, 1991 | 106 | 1991 |
Peptide ligation through click chemistry for the generation of assembled and scaffolded peptides R Franke, C Doll, J Eichler Tetrahedron Letters 46 (26), 4479-4482, 2005 | 101 | 2005 |
Versatility of positional scanning synthetic combinatorial libraries for the identification of individual compounds C Pinilla, JR Appel, SE Blondelle, CT Dooley, J Eichler, JM Ostresh, ... Drug development research 33 (2), 133-145, 1994 | 89 | 1994 |
Forced dimerization of gp130 leads to constitutive STAT3 activation, cytokine-independent growth, and blockade of differentiation of embryonic stem cells C Stuhlmann-Laeisz, S Lang, A Chalaris, P Krzysztof, S Enge, J Eichler, ... Molecular biology of the cell 17 (7), 2986-2995, 2006 | 82 | 2006 |
A monosaccharide residue is sufficient to maintain mouse and human IgG subclass activity and directs IgG effector functions to cellular Fc receptors D Kao, H Danzer, M Collin, A Groß, J Eichler, J Stambuk, G Lauc, A Lux, ... Cell reports 13 (11), 2376-2385, 2015 | 75 | 2015 |
Peptides as protein binding site mimetics J Eichler Current opinion in chemical biology 12 (6), 707-713, 2008 | 70 | 2008 |
Novel α-glucosidase inhibitors identified using multiple cyclic peptide combinatorial libraries J Eichler, AW Lucka, C Pinilla, RA Houghten Molecular diversity 1, 233-240, 1996 | 57 | 1996 |
Application of cellulose paper as support material in simultaneous solid phase peptide synthesis J Eichler, M Beyermann, M Bienert Collection of Czechoslovak chemical communications 54 (6), 1746-1752, 1989 | 55 | 1989 |
Method of performing multiple synthesis of peptides on solid carrier M Lebl, J Eichler, V Pokorny, J Jehnicka, P Mudra, K Zenisek, ... US Patent 5,202,418, 1993 | 53 | 1993 |
Combinatorial libraries: synthesis, screening and application potential R Cortese Walter de Gruyter, 2013 | 48 | 2013 |
Peptide, peptidomimetic, and organic synthetic combinatorial libraries J Eichler, JR Appel, SE Blondelle, CT Dooley, B Döurner, JM Ostresh, ... Medicinal research reviews 15 (6), 481-496, 1995 | 47 | 1995 |
Abrogation of viral interleukin-6 (vIL-6)-induced signaling by intracellular retention and neutralization of vIL-6 with an anti-vIL-6 single-chain antibody selected by phage … M Kovaleva, I Bussmeyer, B Rabe, J Grötzinger, E Sudarman, J Eichler, ... Journal of virology 80 (17), 8510-8520, 2006 | 45 | 2006 |