Fernanda G De Felice
Fernanda G De Felice
Zugehörigkeit unbekannt
Bestätigte E-Mail-Adresse bei bioqmed.ufrj.br
TitelZitiert vonJahr
Aβ oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine
FG De Felice, PT Velasco, MP Lambert, K Viola, SJ Fernandez, ...
Journal of Biological Chemistry 282 (15), 11590-11601, 2007
8192007
Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Aβ oligomers
FG De Felice, MNN Vieira, TR Bomfim, H Decker, PT Velasco, ...
Proceedings of the National Academy of Sciences 106 (6), 1971-1976, 2009
5902009
Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Aβ oligomers
FG De Felice, MNN Vieira, TR Bomfim, H Decker, PT Velasco, ...
Proceedings of the National Academy of Sciences 106 (6), 1971-1976, 2009
5902009
An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers
TR Bomfim, L Forny-Germano, LB Sathler, J Brito-Moreira, JC Houzel, ...
The Journal of clinical investigation 122 (4), 1339-1353, 2012
5822012
Amyloid beta oligomers induce impairment of neuronal insulin receptors
WQ Zhao, FG De Felice, S Fernandez, H Chen, MP Lambert, MJ Quon, ...
The FASEB Journal 22 (1), 246-260, 2008
5292008
Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers
FG De Felice, D Wu, MP Lambert, SJ Fernandez, PT Velasco, PN Lacor, ...
Neurobiology of aging 29 (9), 1334-1347, 2008
4402008
Intranasal insulin as a treatment for Alzheimer’s disease: a review of basic research and clinical evidence
J Freiherr, M Hallschmid, WH Frey, YF Brünner, CD Chapman, ...
CNS drugs 27 (7), 505-514, 2013
3622013
Inflammation, defective insulin signaling, and mitochondrial dysfunction as common molecular denominators connecting type 2 diabetes to Alzheimer disease
FG De Felice, ST Ferreira
Diabetes 63 (7), 2262-2272, 2014
3542014
Soluble protein oligomers as emerging toxins in Alzheimer's and other amyloid diseases
ST Ferreira, MNN Vieira, FG De Felice
IUBMB life 59 (4‐5), 332-345, 2007
3482007
Monoclonal antibodies that target pathological assemblies of Aβ
MP Lambert, PT Velasco, L Chang, KL Viola, S Fernandez, PN Lacor, ...
Journal of neurochemistry 100 (1), 23-35, 2007
3432007
Alzheimer’s disease and insulin resistance: translating basic science into clinical applications
FG De Felice
The Journal of clinical investigation 123 (2), 531-539, 2013
2602013
How does brain insulin resistance develop in Alzheimer's disease?
FG De Felice, MV Lourenco, ST Ferreira
Alzheimer's & Dementia 10, S26-S32, 2014
2392014
Mitochondrial bound hexokinase activity as a preventive antioxidant defense steady-state ADP formation as a regulatory mechanism of membrane potential and reactive oxygen …
WS da-Silva, A Gómez-Puyou, MT de Gómez-Puyou, R Moreno-Sanchez, ...
Journal of Biological Chemistry 279 (38), 39846-39855, 2004
2372004
Inflammation, defective insulin signaling, and neuronal dysfunction in Alzheimer's disease
ST Ferreira, JR Clarke, TR Bomfim, FG De Felice
Alzheimer's & dementia 10, S76-S83, 2014
2362014
Mitochondrial bound hexokinase activity as a preventive antioxidant defense steady-state ADP formation as a regulatory mechanism of membrane potential and reactive oxygen …
WS da-Silva, A Gómez-Puyou, MT de Gómez-Puyou, R Moreno-Sanchez, ...
Journal of Biological Chemistry 279 (38), 39846-39855, 2004
2352004
TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer’s β-amyloid oligomers in mice and monkeys
MV Lourenco, JR Clarke, RL Frozza, TR Bomfim, L Forny-Germano, ...
Cell metabolism 18 (6), 831-843, 2013
2042013
Targeting the neurotoxic species in Alzheimer’s disease: inhibitors of Aβ oligomerization
FG De Felice, MNN Vieira, LM Saraiva, JD Figueroa-Villar, ...
The FASEB journal 18 (12), 1366-1372, 2004
2042004
Mitochondrial creatine kinase activity prevents reactive oxygen species generation antioxidant role of mitochondrial kinase-dependent ADP re-cycling activity
LE Meyer, LB Machado, APSA Santiago, WS da-Silva, FG De Felice, ...
Journal of Biological Chemistry 281 (49), 37361-37371, 2006
1852006
N‐Methyl‐d‐aspartate receptors are required for synaptic targeting of Alzheimer’s toxic amyloid‐β peptide oligomers
H Decker, S Jürgensen, MF Adrover, J Brito‐Moreira, TR Bomfim, ...
Journal of neurochemistry 115 (6), 1520-1529, 2010
1472010
Alzheimer's-associated Aβ oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal
J Pitt, W Roth, P Lacor, AB Smith III, M Blankenship, P Velasco, ...
Toxicology and applied pharmacology 240 (2), 189-197, 2009
1412009
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