Charlotta Scharfe
Charlotta Scharfe
Graduate Student in Bioinformatics, University of Tubingen
Verified email at
Cited by
Cited by
Sequence co-evolution gives 3D contacts and structures of protein complexes
TA Hopf, CPI Schärfe, JP Rodrigues, AG Green, O Kohlbacher, C Sander, ...
Elife 3, e03430, 2014
Mutation effects predicted from sequence co-variation
TA Hopf, JB Ingraham, FJ Poelwijk, CPI Schärfe, M Springer, C Sander, ...
Nature biotechnology 35 (2), 128-135, 2017
The MoSGrid science gateway–a complete solution for molecular simulations
J Krüger, R Grunzke, S Gesing, S Breuers, A Brinkmann, L de la Garza, ...
Journal of Chemical Theory and Computation 10 (6), 2232-2245, 2014
Genetic variation in human drug-related genes
CPI Schärfe, R Tremmel, M Schwab, O Kohlbacher, DS Marks
Genome medicine 9 (1), 1-15, 2017
Activation of lymphoma-associated MyD88 mutations via allostery-induced TIR-domain oligomerization
M Avbelj, OO Wolz, O Fekonja, M Benčina, M Repič, J Mavri, J Krüger, ...
Blood 124 (26), 3896-3904, 2014
Structure and sequence analyses of clustered protocadherins reveal antiparallel interactions that mediate homophilic specificity
JM Nicoludis, SY Lau, CPI Schärfe, DS Marks, WA Weihofen, R Gaudet
Structure 23 (11), 2087-2098, 2015
Structural and functional characterization of the bacterial type III secretion export apparatus
T Dietsche, M Tesfazgi Mebrhatu, MJ Brunner, P Abrusci, J Yan, ...
PLoS pathogens 12 (12), e1006071, 2016
The EVcouplings Python framework for coevolutionary sequence analysis
TA Hopf, AG Green, B Schubert, S Mersmann, CPI Schärfe, JB Ingraham, ...
Bioinformatics 35 (9), 1582-1584, 2019
Antiparallel protocadherin homodimers use distinct affinity-and specificity-mediating regions in cadherin repeats 1-4
JM Nicoludis, BE Vogt, AG Green, CPI Schärfe, DS Marks, R Gaudet
Elife 5, e18449, 2016
Standards‐based metadata management for molecular simulations
R Grunzke, S Breuers, S Gesing, S Herres‐Pawlis, M Kruse, D Blunk, ...
Concurrency and Computation: Practice and Experience 26 (10), 1744-1759, 2014
From the Desktop to the Grid: conversion of KNIME Workflows to gUSE.
L de la Garza, J Krüger, C Schärfe, M Röttig, S Aiche, K Reinert, ...
IWSG, 2013
Population-specific design of de-immunized protein biotherapeutics
B Schubert, C Schärfe, P Dönnes, T Hopf, D Marks, O Kohlbacher
PLoS computational biology 14 (3), e1005983, 2018
Structure, dynamics and implied gating mechanism of a human cyclic nucleotide-gated channel
Y Gofman, C Schärfe, DS Marks, T Haliloglu, N Ben-Tal
PLoS Comput Biol 10 (12), e1003976, 2014
Ballaxy: web services for structural bioinformatics
AK Hildebrandt, D Stöckel, NM Fischer, L de la Garza, J Krüger, S Nickels, ...
Bioinformatics 31 (1), 121-122, 2015
Sequence co-evolution gives 3D contacts and structures of protein complexes. eLife 3
TA Hopf, CPI Schärfe, J Rodrigues, AG Green, O Kohlbacher, C Sander, ...
ClinVAP: a reporting strategy from variants to therapeutic options
B Sürün, CPI Schärfe, MR Divine, J Heinrich, NC Toussaint, ...
Bioinformatics 36 (7), 2316-2317, 2020
Towards Personalized Medicine: Computational Approaches to Support Drug Design and Clinical Decision Making
CPI Schärfe
Universität Tübingen, 2019
Molecular epidemiology as an effective tool for the diagnosis and control of PRRSV infections in pig farms, illustrated using five cases.
T Frey, A Richter, J Skrypski, C Schaerfe, M Hoferer
Berliner und Münchener Tierärztliche Wochenschrift 130 (7/8), 323-331, 2017
Development of a pharmacorphore model for pharmacological chaperones targeting mutant trafficking-deficient CNG channels
CPI Schärfe, J Taeger, P Reuter, NM Fischer, J Krüger, B Wissinger, ...
Journal of Cheminformatics 5 (Suppl 1), O18, 2013
A Critical Assessment of the Impact of Computational Methods on the Productivity in Pharmaceutical Research and Development
C Schärfe
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