| Experimentally increasing titin compliance in a novel mouse model attenuates the Frank-Starling mechanism but has a beneficial effect on diastole M Methawasin, KR Hutchinson, EJ Lee, JE Smith, C Saripalli, CG Hidalgo, ... Biophysical Journal 106 (2), 646a, 2014 | 141 | 2014 |
| Experimentally increasing the compliance of titin through RNA binding motif-20 (RBM20) inhibition improves diastolic function in a mouse model of heart failure with preserved … M Methawasin, JG Strom, RE Slater, V Fernandez, C Saripalli, H Granzier Circulation 134 (15), 1085-1099, 2016 | 110 | 2016 |
| Shortening of the elastic tandem immunoglobulin segment of titin leads to diastolic dysfunction CS Chung, KR Hutchinson, M Methawasin, C Saripalli, JE Smith III, ... Circulation 128 (1), 19-28, 2013 | 107 | 2013 |
| The giant protein titin regulates the length of the striated muscle thick filament P Tonino, B Kiss, J Strom, M Methawasin, JE Smith III, J Kolb, S Labeit, ... Nature communications 8 (1), 1041, 2017 | 101 | 2017 |
| The multifunctional Ca2+/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin's spring elements CG Hidalgo, CS Chung, C Saripalli, M Methawasin, KR Hutchinson, ... Journal of molecular and cellular cardiology 54, 90-97, 2013 | 95 | 2013 |
| Deleting titin’s I-band/A-band junction reveals critical roles for titin in biomechanical sensing and cardiac function HL Granzier, KR Hutchinson, P Tonino, M Methawasin, FW Li, RE Slater, ... Proceedings of the National Academy of Sciences 111 (40), 14589-14594, 2014 | 88 | 2014 |
| Mouse intact cardiac myocyte mechanics: cross-bridge and titin-based stress in unactivated cells NMP King, M Methawasin, J Nedrud, N Harrell, CS Chung, M Helmes, ... Journal of General Physiology 137 (1), 81-91, 2011 | 84 | 2011 |
| Alternative Splicing of Titin Restores Diastolic Function in an HFpEF-Like Genetic Murine Model (TtnΔIAjxn) M Bull, M Methawasin, J Strom, P Nair, K Hutchinson, H Granzier Circulation research 119 (6), 764-772, 2016 | 41 | 2016 |
| Titin based viscosity in ventricular physiology: an integrative investigation of PEVK–actin interactions CS Chung, M Methawasin, OL Nelson, MH Radke, CG Hidalgo, ... Journal of molecular and cellular cardiology 51 (3), 428-434, 2011 | 40 | 2011 |
| Prolactin decreases expression of Runx2, osteoprotegerin, and RANKL in primary osteoblasts derived from tibiae of adult female rats N Charoenphandhu, J Teerapornpuntakit, M Methawasin, K Wongdee, ... Canadian journal of physiology and pharmacology 86 (5), 240-248, 2008 | 37 | 2008 |
| Thin filament length in the cardiac sarcomere varies with sarcomere length but is independent of titin and nebulin J Kolb, F Li, M Methawasin, M Adler, YN Escobar, J Nedrud, CT Pappas, ... Journal of molecular and cellular cardiology 97, 286-294, 2016 | 28 | 2016 |
| Increased titin compliance reduced length-dependent contraction and slowed cross-bridge kinetics in skinned myocardial strips from Rbm20ΔRRM mice HC Pulcastro, PO Awinda, M Methawasin, H Granzier, W Dong, ... Frontiers in Physiology 7, 209314, 2016 | 15 | 2016 |
| The multifunctional calcium/calmodulin-dependent protein kinase II Delta (CaMKIIδ) phosphorylates titin N2B and PEVK spring elements CG Hidalgo, M Methawasin, CS Chung, J Bogomolovas, A Gash, S Labeit, ... Biophysical Journal 102 (3), 559a, 2012 | 5 | 2012 |
| RE: Response by Methawasin and Granzier to Letter on “Experimentally Increasing the Compliance of Titin Through RNA Binding Motif-20 (RBM20) Inhibition Improves Diastolic … M Methawasin, HL Granzier | | 2018 |
| A New Mouse Model in which the Proximal Tandem Ig Element of Titin is Truncated (IGKO)-Assessment of Diastolic Function CS Chung, KR Hutchinson, M Methawasin, NE Cromer, X Luo, C Guo, ... Biophysical Journal 102 (3), 436a, 2012 | | 2012 |
| Effect of Shortening Titin's Proximal IG Segment on Passive Cellular Mechanics M Methawasin, CS Chung, J Nedrud, M Helmes, HL Granzier Biophysical Journal 102 (3), 559a, 2012 | | 2012 |
| Quantification of Titin Based Viscosity: Temperature, Lattice Compression and Integrative Physiology CS Chung, M Methawasin, OL Nelson, M Gotthardt, HL Granzier Biophysical Journal 100 (3), 455a, 2011 | | 2011 |
| Mouse Intact and Skinned Cardiac Myocyte Mechanics: Crossbridge and Titin-Based Stress in Unactivated Cells M Methawasin, NMP King, J Nedrud, CS Chung, M Helmes, HL Granzier Biophysical Journal 100 (3), 127a, 2011 | | 2011 |
| Importance of Titin Based Viscosity in Cardiac Function: an Integrative Study on PEVK-Actin Interactions CS Chung, M Methawasin, J Popper, OL Nelson, M Gotthardt, ... Biophysical Journal 98 (3), 553a, 2010 | | 2010 |
| 2466-Pos Board B452 Length Dependence of Activation (LDA) Studies in Mice Deficient in the N2B Element of Titin Eun-Jeong Lee, Michael Gotthardt, Joshua Nedrud, Bryan Hudson … CS Chung, M Methawasin, OL Nelson | | |
