Alexandra Trkola
Alexandra Trkola
Professor of Medical Virology, University of Zurich
Verified email at - Homepage
Cited by
Cited by
CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5
A Trkola, T Dragic, J Arthos, JM Binley, WC Olson, GP Allaway, ...
Nature 384 (6605), 184-187, 1996
Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1
A Trkola, M Purtscher, T Muster, C Ballaun, A Buchacher, N Sullivan, ...
Journal of virology 70 (2), 1100-1108, 1996
A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1
T Muster, F Steindl, M Purtscher, A Trkola, A Klima, G Himmler, F Rüker, ...
Journal of virology 67 (11), 6642-6647, 1993
Co-receptors for HIV-1 entry
JP Moore, A Trkola, T Dragic
Current opinion in immunology 9 (4), 551-562, 1997
Generation of human monoclonal antibodies against HIV-1 proteins; electrofusion and Epstein-Barr virus transformation for peripheral blood lymphocyte immortalization
A Buchacher, R Predl, K Strutzenberger, W Steinfellner, A Trkola, ...
AIDS research and human retroviruses 10 (4), 359-369, 1994
Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies
A Trkola, H Kuster, P Rusert, B Joos, M Fischer, C Leemann, A Manrique, ...
Nature medicine 11 (6), 615-622, 2005
Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG
A Trkola, AB Pomales, H Yuan, B Korber, PJ Maddon, GP Allaway, ...
Journal of virology 69 (11), 6609-6617, 1995
A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5
T Dragic, A Trkola, DAD Thompson, EG Cormier, FA Kajumo, E Maxwell, ...
Proceedings of the National Academy of Sciences 97 (10), 5639-5644, 2000
SCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo
JM Strizki, S Xu, NE Wagner, L Wojcik, J Liu, Y Hou, M Endres, A Palani, ...
Proceedings of the National Academy of Sciences 98 (22), 12718-12723, 2001
A broadly neutralizing human monoclonal antibody against gp41 of human immunodeficiency virus type 1
AIDS research and human retroviruses 10 (12), 1651-1658, 1994
HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use
A Trkola, SE Kuhmann, JM Strizki, E Maxwell, T Ketas, T Morgan, ...
Proceedings of the National Academy of Sciences 99 (1), 395-400, 2002
Cross-neutralizing activity against divergent human immunodeficiency virus type 1 isolates induced by the gp41 sequence ELDKWAS
T Muster, R Guinea, A Trkola, M Purtscher, A Klima, F Steindl, P Palese, ...
Journal of virology 68 (6), 4031-4034, 1994
Potent, broad-spectrum inhibition of human immunodeficiency virus type 1 by the CCR5 monoclonal antibody PRO 140
A Trkola, TJ Ketas, KA Nagashima, L Zhao, T Cilliers, L Morris, JP Moore, ...
Journal of virology 75 (2), 579-588, 2001
Neutralization of the human immunodeficiency virus type 1 primary isolate JR-FL by human monoclonal antibodies correlates with antibody binding to the oligomeric form of the …
TR Fouts, JM Binley, A Trkola, JE Robinson, JP Moore
Journal of Virology 71 (4), 2779-2785, 1997
HIV rebounds from latently infected cells, rather than from continuing low-level replication
B Joos, M Fischer, H Kuster, SK Pillai, JK Wong, J Böni, B Hirschel, ...
Proceedings of the National Academy of Sciences 105 (43), 16725-16730, 2008
Amino-terminal substitutions in the CCR5 coreceptor impair gp120 binding and human immunodeficiency virus type 1 entry
T Dragic, A Trkola, SW Lin, KA Nagashima, F Kajumo, L Zhao, WC Olson, ...
Journal of virology 72 (1), 279-285, 1998
Analysis of the mechanism by which the small-molecule CCR5 antagonists SCH-351125 and SCH-350581 inhibit human immunodeficiency virus type 1 entry
F Tsamis, S Gavrilov, F Kajumo, C Seibert, S Kuhmann, T Ketas, A Trkola, ...
Journal of virology 77 (9), 5201-5208, 2003
Immunological and virological analyses of persons infected by human immunodeficiency virus type 1 while participating in trials of recombinant gp120 subunit vaccines
RI Connor, BTM Korber, BS Graham, BH Hahn, DD Ho, BD Walker, ...
Journal of virology 72 (2), 1552-1576, 1998
HIV-1–specific immune responses in subjects who temporarily contain virus replication after discontinuation of highly active antiretroviral therapy
GM Ortiz, DF Nixon, A Trkola, J Binley, X Jin, S Bonhoeffer, PJ Kuebler, ...
The Journal of clinical investigation 104 (6), R13-R18, 1999
The BBXB motif of RANTES is the principal site for heparin binding and controls receptor selectivity
AEI Proudfoot, S Fritchley, F Borlat, JP Shaw, F Vilbois, C Zwahlen, ...
Journal of Biological Chemistry 276 (14), 10620-10626, 2001
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