| The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data A McKenna, M Hanna, E Banks, A Sivachenko, K Cibulskis, A Kernytsky, ... Genome research 20 (9), 1297-1303, 2010 | 24493 | 2010 |
| A framework for variation discovery and genotyping using next-generation DNA sequencing data MA DePristo, E Banks, R Poplin, KV Garimella, JR Maguire, C Hartl, ... Nature genetics 43 (5), 491-498, 2011 | 11593 | 2011 |
| A map of human genome variation from population scale sequencing 1000 Genomes Project Consortium Nature 467 (7319), 1061, 2010 | 8755 | 2010 |
| An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells D Rohle, J Popovici-Muller, N Palaskas, S Turcan, C Grommes, ... Science 340 (6132), 626-630, 2013 | 1265 | 2013 |
| CRISPR-Cas9 gene editing for sickle cell disease and β-thalassemia H Frangoul, D Altshuler, MD Cappellini, YS Chen, J Domm, BK Eustace, ... New England Journal of Medicine 384 (3), 252-260, 2021 | 1259 | 2021 |
| Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation F Wang, J Travins, B DeLaBarre, V Penard-Lacronique, S Schalm, ... Science 340 (6132), 622-626, 2013 | 941 | 2013 |
| Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia K Musunuru, JP Pirruccello, R Do, GM Peloso, C Guiducci, C Sougnez, ... New England Journal of Medicine 363 (23), 2220-2227, 2010 | 776 | 2010 |
| Demographic history and rare allele sharing among human populations S Gravel, BM Henn, RN Gutenkunst, AR Indap, GT Marth, AG Clark, F Yu, ... Proceedings of the National Academy of Sciences 108 (29), 11983-11988, 2011 | 707 | 2011 |
| Using multiple structure alignments, fast model building, and energetic analysis in fold recognition and homology modeling D Petrey, Z Xiang, CL Tang, L Xie, M Gimpelev, T Mitros, CS Soto, ... Proteins: Structure, Function, and Bioinformatics 53 (S6), 430-435, 2003 | 394 | 2003 |
| MTAP deletions in cancer create vulnerability to targeting of the MAT2A/PRMT5/RIOK1 axis K Marjon, MJ Cameron, P Quang, MF Clasquin, E Mandley, K Kunii, ... Cell reports 15 (3), 574-587, 2016 | 342 | 2016 |
| Transmembrane helix predictions revisited CP Chen, A Kernytsky, B Rost Protein Science 11 (12), 2774-2791, 2002 | 270 | 2002 |
| IDH2 mutation-induced histone and DNA hypermethylation is progressively reversed by small-molecule inhibition A Kernytsky, F Wang, E Hansen, S Schalm, K Straley, C Gliser, H Yang, ... Blood, The Journal of the American Society of Hematology 125 (2), 296-303, 2015 | 180 | 2015 |
| Membrane protein prediction methods M Punta, LR Forrest, H Bigelow, A Kernytsky, J Liu, B Rost Methods 41 (4), 460-474, 2007 | 154 | 2007 |
| Targeted exon sequencing by in‐solution hybrid selection B Blumenstiel, K Cibulskis, S Fisher, M DeFelice, A Barry, T Fennell, ... Current Protocols in Human Genetics 66 (1), 18.4. 1-18.4. 24, 2010 | 88 | 2010 |
| Static benchmarking of membrane helix predictions A Kernytsky, B Rost Nucleic acids research 31 (13), 3642-3644, 2003 | 61 | 2003 |
| Evaluation of homology-independent CRISPR-Cas9 off-target assessment methods HG Chaudhari, J Penterman, HJ Whitton, SJ Spencer, N Flanagan, ... The CRISPR Journal 3 (6), 440-453, 2020 | 43 | 2020 |
| Using genetic algorithms to select most predictive protein features A Kernytsky, B Rost Proteins: Structure, Function, and Bioinformatics 75 (1), 75-88, 2009 | 28 | 2009 |
| Altshuler, 695 D., Gabriel, S., Daly, M., et al.(2010). The Genome Analysis Toolkit: a MapReduce framework for analyzing 696 next-generation DNA sequencing data A McKenna, M Hanna, E Banks, A Sivachenko, K Cibulskis, A Kernytsky, ... Genome res 20, 1297-1303, 0 | 22* | |
| CRISPR/Cas9 Genome Editing to Treat Sickle Cell Disease and B-Thalassemia: Re-Creating Genetic Variants to Upregulate Fetal Hemoglobin Appear Well-Tolerated, Effective and Durable. MI Lin, E Paik, B Mishra, D Burkhardt, A Kernytsky, M Pettiglio, YS Chen, ... Blood 130, 284, 2017 | 20 | 2017 |
| A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model F Wang, J Travins, Z Lin, Y Si, Y Chen, J Powe, S Murray, D Zhu, E Artin, ... Journal of Inherited Metabolic Disease 39, 807-820, 2016 | 18 | 2016 |
Kristian CibulskisBroad InstituteVerified email at broadinstitute.org
