Eugen Rempel
Eugen Rempel
Center for Molecular Pathology , Heidelberg University
Bestätigte E-Mail-Adresse bei dkfz.de
Titel
Zitiert von
Zitiert von
Jahr
Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach
AK Krug, R Kolde, JA Gaspar, E Rempel, NV Balmer, K Meganathan, ...
Archives of toxicology 87 (1), 123-143, 2013
1862013
Toxicogenomics directory of chemically exposed human hepatocytes
M Grinberg, RM Stöber, K Edlund, E Rempel, P Godoy, R Reif, A Widera, ...
Archives of toxicology 88 (12), 2261-2287, 2014
1122014
Design principles of concentration-dependent transcriptome deviations in drug-exposed differentiating stem cells
T Waldmann, E Rempel, NV Balmer, A König, R Kolde, JA Gaspar, ...
Chemical research in toxicology 27 (3), 408-420, 2014
812014
Integration of light and metabolic signals for stem cell activation at the shoot apical meristem
A Pfeiffer, D Janocha, Y Dong, A Medzihradszky, S Schöne, G Daum, ...
Elife 5, e17023, 2016
742016
A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors
E Rempel, L Hoelting, T Waldmann, NV Balmer, S Schildknecht, ...
Archives of toxicology 89 (9), 1599-1618, 2015
602015
Size matters: Dissecting key parameters for panel‐based tumor mutational burden analysis
I Buchhalter, E Rempel, V Endris, M Allgäuer, O Neumann, AL Volckmar, ...
International Journal of Cancer 144 (4), 848-858, 2019
562019
Implementing tumor mutational burden (TMB) analysis in routine diagnostics—a primer for molecular pathologists and clinicians
M Allgäuer, J Budczies, P Christopoulos, V Endris, A Lier, E Rempel, ...
Translational lung cancer research 7 (6), 703, 2018
562018
From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug …
NV Balmer, S Klima, E Rempel, VN Ivanova, R Kolde, MK Weng, ...
Archives of toxicology 88 (7), 1451-1468, 2014
562014
Measurement of tumor mutational burden (TMB) in routine molecular diagnostics: in silico and real‐life analysis of three larger gene panels
V Endris, I Buchhalter, M Allgäuer, E Rempel, A Lier, AL Volckmar, ...
International journal of cancer 144 (9), 2303-2312, 2019
412019
Human pluripotent stem cell based developmental toxicity assays for chemical safety screening and systems biology data generation
V Shinde, S Klima, PS Sureshkumar, K Meganathan, S Jagtap, E Rempel, ...
JoVE (Journal of Visualized Experiments), e52333, 2015
372015
Glycerol-3-phosphate acyltransferase 1 promotes tumor cell migration and poor survival in ovarian carcinoma
R Marchan, B Büttner, J Lambert, K Edlund, I Glaeser, M Blaszkewicz, ...
Cancer Research 77 (17), 4589-4601, 2017
332017
Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Tox ukn and STOP-Tox ukk tests
V Shinde, L Hoelting, SP Srinivasan, J Meisig, K Meganathan, S Jagtap, ...
Archives of toxicology 91 (2), 839-864, 2017
302017
Optimizing panel-based tumor mutational burden (TMB) measurement
J Budczies, M Allgäuer, K Litchfield, E Rempel, P Christopoulos, D Kazdal, ...
Annals of Oncology 30 (9), 1496-1506, 2019
272019
Motor neurons control blood vessel patterning in the developing spinal cord
P Himmels, I Paredes, H Adler, A Karakatsani, R Luck, HH Marti, ...
Nature communications 8 (1), 1-16, 2017
272017
Hepatotoxicity of piperazine designer drugs: up-regulation of key enzymes of cholesterol and lipid biosynthesis
MD Arbo, S Melega, R Stöber, M Schug, E Rempel, J Rahnenführer, ...
Archives of toxicology 90 (12), 3045-3060, 2016
252016
EDI3 links choline metabolism to integrin expression, cell adhesion and spreading
MS Lesjak, R Marchan, JD Stewart, E Rempel, J Rahnenführer, ...
Cell adhesion & migration 8 (5), 499-508, 2014
252014
Combined targeted DNA and RNA sequencing of advanced NSCLC in routine molecular diagnostics: Analysis of the first 3,000 Heidelberg cases
AL Volckmar, J Leichsenring, M Kirchner, P Christopoulos, O Neumann, ...
International Journal of Cancer 145 (3), 649-661, 2019
222019
Stem cell transcriptome responses and corresponding biomarkers that indicate the transition from adaptive responses to cytotoxicity
T Waldmann, M Grinberg, A Konig, E Rempel, S Schildknecht, M Henry, ...
Chemical research in toxicology 30 (4), 905-922, 2017
212017
Spatial and temporal heterogeneity of panel-based tumor mutational burden in pulmonary adenocarcinoma: separating biology from technical artifacts
D Kazdal, V Endris, M Allgäuer, M Kriegsmann, J Leichsenring, ...
Journal of Thoracic Oncology 14 (11), 1935-1947, 2019
162019
The molecular signature of AML with increased ALDH activity suggests a stem cell origin
R Blume, E Rempel, L Manta, BR Saeed, W Wang, S Raffel, O Ermakova, ...
Leukemia & lymphoma 59 (9), 2201-2210, 2018
122018
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