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Robert Bone
Robert Bone
Indiana University School of Medicine
Bestätigte E-Mail-Adresse bei iu.edu
Titel
Zitiert von
Zitiert von
Jahr
Calcium-independent phospholipases A2 and their roles in biological processes and diseases
S Ramanadham, T Ali, JW Ashley, RN Bone, WD Hancock, X Lei
Journal of lipid research 56 (9), 1643-1668, 2015
1982015
Endoplasmic reticulum stress alters ryanodine receptor function in the murine pancreatic β cell
WR Yamamoto, RN Bone, P Sohn, F Syed, CA Reissaus, AL Mosley, ...
Journal of Biological Chemistry 294 (1), 168-181, 2019
1012019
Regeneration of pancreatic non-β endocrine cells in adult mice following a single diabetes-inducing dose of streptozotocin
Y Zhang, Y Zhang, RN Bone, W Cui, JB Peng, GP Siegal, H Wang, H Wu
PloS one 7 (5), e36675, 2012
772012
Impaired store-operated calcium entry and STIM1 loss lead to reduced insulin secretion and increased endoplasmic reticulum stress in the diabetic β-cell
T Kono, X Tong, S Taleb, RN Bone, H Iida, CC Lee, P Sohn, P Gilon, ...
Diabetes 67 (11), 2293-2304, 2018
612018
Polarization of macrophages toward M2 phenotype is favored by reduction in iPLA2β (group VIA phospholipase A2)
JW Ashley, WD Hancock, AJ Nelson, RN Bone, MT Hubert, M Wohltmann, ...
Journal of Biological Chemistry 291 (44), 23268-23281, 2016
472016
Inhibition of Ca2+-Independent Phospholipase A2β (iPLA2β) Ameliorates Islet Infiltration and Incidence of Diabetes in NOD Mice
RN Bone, Y Gai, V Magrioti, MG Kokotou, T Ali, X Lei, HM Tse, G Kokotos, ...
Diabetes 64 (2), 541-554, 2015
462015
Characterization of FKGK18 as Inhibitor of Group VIA Ca2+-Independent Phospholipase A2 (iPLA2β): Candidate Drug for Preventing Beta-Cell Apoptosis and …
T Ali, G Kokotos, V Magrioti, RN Bone, JA Mobley, W Hancock, ...
PloS one 8 (8), e71748, 2013
442013
Combination immunotherapy for type 1 diabetes
RN Bone, C Evans-Molina
Current diabetes reports 17 (7), 50, 2017
402017
Genetic modulation of islet β-cell iPLA2β expression provides evidence for its impact on β-cell apoptosis and autophagy
X Lei, RN Bone, T Ali, M Wohltmann, Y Gai, KJ Goodwin, AE Bohrer, ...
Islets 5 (1), 29-44, 2013
362013
Evidence of Contribution of iPLA2β-Mediated Events During Islet β-Cell Apoptosis Due to Proinflammatory Cytokines Suggests a Role for iPLA2β in T1D …
X Lei, RN Bone, T Ali, S Zhang, A Bohrer, HM Tse, KR Bidasee, ...
Endocrinology 155 (9), 3352-3364, 2014
322014
Cigarette smoke exposure impairs β-cell function through activation of oxidative stress and ceramide accumulation
X Tong, Z Chaudhry, CC Lee, RN Bone, S Kanojia, J Maddatu, P Sohn, ...
Molecular Metabolism 37, 100975, 2020
272020
A computational approach for defining a signature of β-cell Golgi stress in diabetes
RN Bone, O Oyebamiji, S Talware, S Selvaraj, P Krishnan, F Syed, H Wu, ...
Diabetes 69 (11), 2364-2376, 2020
262020
Gene transfer of active Akt1 by an infectivity-enhanced adenovirus impacts β-cell survival and proliferation differentially in vitro and in vivo
RN Bone, M Icyuz, Y Zhang, Y Zhang, W Cui, H Wang, JB Peng, ...
Islets 4 (6), 366-378, 2012
252012
Lipid mediators and biomarkers associated with type 1 diabetes development
AJ Nelson, DJ Stephenson, RN Bone, CL Cardona, MA Park, YG Tusing, ...
JCI insight 5 (16), 2020
192020
Offspring of obese dams exhibit sex-differences in pancreatic heparan sulfate glycosaminoglycans and islet insulin secretion
J Casasnovas, CL Damron, J Jarrell, KS Orr, RN Bone, ...
Frontiers in Endocrinology 12, 658439, 2021
122021
A high-fat diet catalyzes progression to hyperglycemia in mice with selective impairment of insulin action in Glut4-expressing tissues
AM Reilly, S Yan, M Huang, SD Abhyankar, JM Conley, RN Bone, ...
Journal of Biological Chemistry 298 (1), 2022
112022
A discovery-based proteomics approach identifies protein disulphide isomerase (PDIA1) as a biomarker of β cell stress in type 1 diabetes
F Syed, D Singhal, K Raedschelders, P Krishnan, RN Bone, ...
EBioMedicine 87, 2023
82023
Nmp4, a regulator of induced osteoanabolism, also influences insulin secretion and sensitivity
J Bidwell, SA Tersey, M Adaway, RN Bone, A Creecy, A Klunk, ...
Calcified tissue international 110 (2), 244-259, 2022
42022
SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells
H Iida, T Kono, CC Lee, P Krishnan, MC Arvin, SA Weaver, TS Jarvela, ...
Diabetologia 66 (11), 2042-2061, 2023
32023
Reduced ß cell SPCA1 leads to impaired calcium oscillations and decreased autophagy
RN Bone, T Kono, C Evans-Molina
Diabetes 67 (Supplement_1), 2018
22018
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