Martin Carroll
Martin Carroll
Associate Professor, University of Pennsylvania
Verified email at mail.med.upenn.edu
Title
Cited by
Cited by
Year
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia
Cancer Genome Atlas Research Network
New England Journal of Medicine 368 (22), 2059-2074, 2013
28102013
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting α-ketoglutarate to 2-hydroxyglutarate
PS Ward, J Patel, DR Wise, O Abdel-Wahab, BD Bennett, HA Coller, ...
Cancer cell 17 (3), 225-234, 2010
17032010
CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins
M Carroll, S Ohno-Jones, S Tamura, E Buchdunger, J Zimmermann, ...
Blood, The Journal of the American Society of Hematology 90 (12), 4947-4952, 1997
6871997
Survival of acute myeloid leukemia cells requires PI3 kinase activation
Q Xu, SE Simpson, TJ Scialla, A Bagg, M Carroll
Blood 102 (3), 972-980, 2003
5582003
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression
O Abdel-Wahab, M Adli, LM LaFave, J Gao, T Hricik, AH Shih, S Pandey, ...
Cancer cell 22 (2), 180-193, 2012
4892012
An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells
ML Guzman, RM Rossi, S Neelakantan, X Li, CA Corbett, DC Hassane, ...
Blood, The Journal of the American Society of Hematology 110 (13), 4427-4435, 2007
4282007
The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells
LP Vu, BF Pickering, Y Cheng, S Zaccara, D Nguyen, G Minuesa, T Chou, ...
Nature medicine 23 (11), 1369, 2017
3742017
Human acute myelogenous leukemia stem cells are rare and heterogeneous when assayed in NOD/SCID/IL2Rγc-deficient mice
JE Sarry, K Murphy, R Perry, PV Sanchez, A Secreto, C Keefer, ...
The Journal of clinical investigation 121 (1), 384-395, 2011
3702011
Preclinical targeting of human acute myeloid leukemia and myeloablation using chimeric antigen receptor–modified T cells
S Gill, SK Tasian, M Ruella, O Shestova, Y Li, DL Porter, M Carroll, ...
Blood, The Journal of the American Society of Hematology 123 (15), 2343-2354, 2014
3272014
The TEL/platelet-derived growth factor β receptor (PDGFβR) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGFβR kinase …
M Carroll, MH Tomasson, GF Barker, TR Golub, DG Gilliland
Proceedings of the National Academy of Sciences 93 (25), 14845-14850, 1996
3141996
Distinct IL-2 receptor signaling pattern in CD4+ CD25+ regulatory T cells
SJ Bensinger, PT Walsh, J Zhang, M Carroll, R Parsons, JC Rathmell, ...
The Journal of Immunology 172 (9), 5287-5296, 2004
3112004
AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3
M Wunderlich, FS Chou, KA Link, B Mizukawa, RL Perry, M Carroll, ...
Leukemia 24 (10), 1785-1788, 2010
2942010
Lestaurtinib (CEP701) is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders
EO Hexner, C Serdikoff, M Jan, CR Swider, C Robinson, S Yang, ...
Blood 111 (12), 5663-5671, 2008
2692008
CD33-specific chimeric antigen receptor T cells exhibit potent preclinical activity against human acute myeloid leukemia
SS Kenderian, M Ruella, O Shestova, M Klichinsky, V Aikawa, ...
Leukemia 29 (8), 1637-1647, 2015
2652015
Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR
SM Ranuncolo, JM Polo, J Dierov, M Singer, T Kuo, J Greally, R Green, ...
Nature immunology 8 (7), 705-714, 2007
2632007
Chemotherapy-resistant human acute myeloid leukemia cells are not enriched for leukemic stem cells but require oxidative metabolism
T Farge, E Saland, F de Toni, N Aroua, M Hosseini, R Perry, C Bosc, ...
Cancer discovery 7 (7), 716-735, 2017
2332017
Tribbles homolog 2 inactivates C/EBPα and causes acute myelogenous leukemia
K Keeshan, Y He, BJ Wouters, O Shestova, L Xu, H Sai, CG Rodriguez, ...
Cancer cell 10 (5), 401-411, 2006
2312006
Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data
DC Hassane, ML Guzman, C Corbett, X Li, R Abboud, F Young, ...
Blood, The Journal of the American Society of Hematology 111 (12), 5654-5662, 2008
2152008
DNMT3A and IDH mutations in acute myeloid leukemia and other myeloid malignancies: associations with prognosis and potential treatment strategies
AP Im, AR Sehgal, MP Carroll, BD Smith, A Tefferi, DE Johnson, ...
Leukemia 28 (9), 1774-1783, 2014
2142014
DUB-1, a deubiquitinating enzyme with growth-suppressing activity
Y Zhu, M Carroll, FR Papa, M Hochstrasser, AD D'Andrea
Proceedings of the National Academy of Sciences 93 (8), 3275-3279, 1996
2051996
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