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James D. West
James D. West
Professor of Biochemistry & Molecular Biology; The College of Wooster
Bestätigte E-Mail-Adresse bei wooster.edu - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein
LJ Marnett, JN Riggins, JD West
The Journal of Clinical Investigation 111 (5), 583-593, 2003
6072003
Endogenous reactive intermediates as modulators of cell signaling and cell death
JD West, LJ Marnett
Chemical Research in Toxicology 19 (2), 173-194, 2006
3742006
Activation of heat shock and antioxidant responses by the natural product celastrol: transcriptional signatures of a thiol-targeted molecule
A Trott, JD West, L Klaić, SD Westerheide, RB Silverman, RI Morimoto, ...
Molecular Biology of the Cell 19 (3), 1104-1112, 2008
2622008
Alterations in gene expression induced by the lipid peroxidation product, 4-hydroxy-2-nonenal
JD West, LJ Marnett
Chemical Research in Toxicology 18 (11), 1642-1653, 2005
1542005
Induction of apoptosis in colorectal carcinoma cells treated with 4-hydroxy-2-nonenal and structurally related aldehydic products of lipid peroxidation
JD West, C Ji, ST Duncan, V Amarnath, C Schneider, CJ Rizzo, AR Brash, ...
Chemical Research in Toxicology 17 (4), 453-462, 2004
882004
The yeast Hsp70 Ssa1 is a sensor for activation of the heat shock response by thiol-reactive compounds
Y Wang, PA Gibney, JD West, KA Morano
Molecular Biology of the Cell 23 (17), 3290-3298, 2012
752012
Small Molecule Activators of the Heat Shock Response: Chemical Properties, Molecular Targets, and Therapeutic Promise
JD West, Y Wang, KA Morano
Chemical Research in Toxicology 25 (10), 2036–2053, 2012
682012
Modulation of DNA fragmentation factor 40 nuclease activity by poly (ADP-ribose) polymerase-1
JD West, C Ji, LJ Marnett
Journal of Biological Chemistry 280 (15), 15141-15147, 2005
362005
Enhanced Toxicity of the Protein Cross-Linkers Divinyl Sulfone and Diethyl Acetylenedicarboxylate in Comparison to Related Monofunctional Electrophiles
JD West, CE Stamm, HA Brown, SL Justice, KA Morano
Chemical Research in Toxicology 24 (9), 1457–1459, 2011
312011
Trapping redox partnerships in oxidant-sensitive proteins with a small, thiol-reactive cross-linker
KM Allan, MA Loberg, J Chepngeno, JE Hurtig, S Tripathi, MG Kang, ...
Free Radical Biology and Medicine 101, 356-366, 2016
192016
Redox requirements for ubiquitin-like urmylation of Ahp1, a 2-Cys peroxiredoxin from yeast
C Brachmann, L Kaduhr, A Jüdes, KE Ravichandran, JD West, S Glatt, ...
Redox biology 30, 101438, 2020
182020
Bifunctional Electrophiles Cross-Link Thioredoxins with Redox Relay Partners in Cells
MR Naticchia, HA Brown, FJ Garcia, AM Lamade, SL Justice, RP Herrin, ...
Chemical Research in Toxicology 26 (3), 490-497, 2013
172013
Piecing Together How Peroxiredoxins Maintain Genomic Stability
JD West, TJ Roston, JB David, KM Allan, MA Loberg
Antioxidants 7 (12), 177, 2018
152018
Structure−Activity Comparison of the Cytotoxic Properties of Diethyl Maleate and Related Molecules: Identification of Diethyl Acetylenedicarboxylate as a Thiol Cross-Linking Agent
JD West, CE Stamm, PJ Kingsley
Chemical Research in Toxicology 24 (1), 81-88, 2010
142010
Aromatic Residues at the Dimer-Dimer Interface in the Peroxiredoxin Tsa1 Facilitate Decamer Formation and Biological Function
MA Loberg, JE Hurtig, AH Graff, KM Allan, JA Buchan, MK Spencer, ...
Chemical Research in Toxicology 32 (3), 474-484, 2019
122019
Pronounced Toxicity Differences between Homobifunctional Protein Cross-Linkers and Analogous Monofunctional Electrophiles
MK Spencer, NP Radzinski, S Tripathi, S Chowdhury, RP Herrin, ...
Chemical Research in Toxicology 26 (11), 1720-1729, 2013
92013
Experimental Approaches for Investigating Disulfide-Based Redox Relays in Cells
JD West
Chemical Research in Toxicology 35 (10), 1676-1689, 2022
72022
Urm1, not quite a ubiquitin-like modifier?
L Kaduhr, C Brachmann, KE Ravichandran, JD West, S Glatt, R Schaffrath
Microbial Cell 8 (11), 256-261, 2021
32021
Identifying Interaction Partners of Yeast Protein Disulfide Isomerases Using a Small Thiol-Reactive Cross-Linker: Implications for Secretory Pathway Proteostasis
BJ Freije, WM Freije, TU Do, GE Adkins, A Bruch, JE Hurtig, KA Morano, ...
Chemical Research in Toxicology 35 (2), 326-336, 2022
22022
Broader than expected tolerance for substitutions in the WCGPCK catalytic motif of yeast thioredoxin 2
SL Vicker, EN Maina, AK Showalter, N Tran, EE Davidson, MR Bailey, ...
Free Radical Biology and Medicine 178, 308-313, 2022
12022
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