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Michael G. Roper
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A fully integrated microfluidic genetic analysis system with sample-in–answer-out capability
CJ Easley, JM Karlinsey, JM Bienvenue, LA Legendre, MG Roper, ...
Proceedings of the National Academy of Sciences 103 (51), 19272-19277, 2006
7062006
Microfluidic chip for continuous monitoring of hormone secretion from live cells using an electrophoresis-based immunoassay
MG Roper, JG Shackman, GM Dahlgren, RT Kennedy
Analytical chemistry 75 (18), 4711-4717, 2003
2992003
A simple, valveless microfluidic sample preparation device for extraction and amplification of DNA from nanoliter-volume samples
LA Legendre, JM Bienvenue, MG Roper, JP Ferrance, JP Landers
Analytical chemistry 78 (5), 1444-1451, 2006
2282006
Roles of insulin receptor substrate-1, phosphatidylinositol 3-kinase, and release of intracellular Ca2+ stores in insulin-stimulated insulin secretion in β-cells
CA Aspinwall, WJ Qian, MG Roper, RN Kulkarni, CR Kahn, RT Kennedy
Journal of Biological Chemistry 275 (29), 22331-22338, 2000
2202000
Advances in polymerase chain reaction on microfluidic chips
MG Roper, CJ Easley, JP Landers
Analytical chemistry 77 (12), 3887-3894, 2005
2172005
Microfluidics-to-mass spectrometry: a review of coupling methods and applications
X Wang, L Yi, N Mukhitov, AM Schrell, R Dhumpa, MG Roper
Journal of Chromatography A 1382, 98-116, 2015
1352015
Measurement of DCF fluorescence as a measure of reactive oxygen species in murine islets of Langerhans
X Wang, MG Roper
Analytical Methods 6 (9), 3019-3024, 2014
1292014
Infrared temperature control system for a completely noncontact polymerase chain reaction in microfluidic chips
MG Roper, CJ Easley, LA Legendre, JAC Humphrey, JP Landers
Analytical chemistry 79 (4), 1294-1300, 2007
1212007
Islet secretory defect in insulin receptor substrate 1 null mice is linked with reduced calcium signaling and expression of sarco (endo) plasmic reticulum Ca2+-ATPase (SERCA …
RN Kulkarni, MG Roper, G Dahlgren, DQ Shih, LM Kauri, JL Peters, ...
Diabetes 53 (6), 1517-1525, 2004
1012004
Recent advances in microfluidic detection systems
CA Baker, CT Duong, A Grimley, MG Roper
Bioanalysis 1 (5), 967-975, 2009
992009
Simultaneous monitoring of insulin and islet amyloid polypeptide secretion from islets of Langerhans on a microfluidic device
AR Lomasney, L Yi, MG Roper
Analytical chemistry 85 (16), 7919-7925, 2013
822013
Synchronized stimulation and continuous insulin sensing in a microfluidic human Islet on a Chip designed for scalable manufacturing
AL Glieberman, BD Pope, JF Zimmerman, Q Liu, JP Ferrier, JHR Kenty, ...
Lab on a Chip 19 (18), 2993-3010, 2019
802019
Integrated perfusion and separation systems for entrainment of insulin secretion from islets of Langerhans
L Yi, X Wang, R Dhumpa, AM Schrell, N Mukhitov, MG Roper
Lab on a Chip 15 (3), 823-832, 2015
762015
Microfluidic system for generation of sinusoidal glucose waveforms for entrainment of islets of Langerhans
X Zhang, A Grimley, R Bertram, MG Roper
Analytical chemistry 82 (15), 6704-6711, 2010
702010
Microfluidic perfusion system for automated delivery of temporal gradients to islets of Langerhans
X Zhang, MG Roper
Analytical chemistry 81 (3), 1162-1168, 2009
672009
Effect of the Insulin Mimetic L-783,281 on Intracellular [Ca2+] and Insulin Secretion From Pancreatic β-Cells
MG Roper, W Qian, BB Zhang, RN Kulkarni, CR Kahn, RT Kennedy
Diabetes 51 (suppl_1), S43-S49, 2002
672002
Online coupling of digital microfluidic devices with mass spectrometry detection using an eductor with electrospray ionization
CA Baker, MG Roper
Analytical chemistry 84 (6), 2955-2960, 2012
622012
Microfluidic-enabled quantitative measurements of insulin release dynamics from single islets of Langerhans in response to 5-palmitic acid hydroxy stearic acid
B Bandak, L Yi, MG Roper
Lab on a Chip 18 (18), 2873-2882, 2018
592018
Transport and separation of biomolecular cargo on paramagnetic colloidal particles in a magnetic ratchet
P Tierno, SV Reddy, MG Roper, TH Johansen, TM Fischer
The Journal of Physical Chemistry B 112 (12), 3833-3837, 2008
552008
Negative feedback synchronizes islets of Langerhans
R Dhumpa, TM Truong, X Wang, R Bertram, MG Roper
Biophysical journal 106 (10), 2275-2282, 2014
502014
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