| Model-based integrated optimization and evaluation of a multi-step ion exchange chromatography TC Huuk, T Hahn, A Osberghaus, J Hubbuch Separation and Purification Technology 136, 207-222, 2014 | 77 | 2014 |
| Simulating and optimizing preparative protein chromatography with ChromX T Hahn, T Huuk, V Heuveline, J Hubbuch Journal of Chemical Education 92 (9), 1497-1502, 2015 | 57 | 2015 |
| UV absorption‐based inverse modeling of protein chromatography T Hahn, P Baumann, T Huuk, V Heuveline, J Hubbuch Engineering in Life Sciences 16 (2), 99-106, 2016 | 45 | 2016 |
| Modeling of complex antibody elution behavior under high protein load densities in ion exchange chromatography using an asymmetric activity coefficient TC Huuk, T Hahn, K Doninger, J Griesbach, S Hepbildikler, J Hubbuch Biotechnology journal 12 (3), 1600336, 2017 | 35 | 2017 |
| A versatile noninvasive method for adsorber quantification in batch and column chromatography based on the ionic capacity TC Huuk, T Briskot, T Hahn, J Hubbuch Biotechnology progress 32 (3), 666-677, 2016 | 30 | 2016 |
| Calibration‐free inverse modeling of ion‐exchange chromatography in industrial antibody purification T Hahn, T Huuk, A Osberghaus, K Doninger, S Nath, S Hepbildikler, ... Engineering in Life Sciences 16 (2), 107-113, 2016 | 29 | 2016 |
| Protein adsorption on ion exchange adsorbers: A comparison of a stoichiometric and non-stoichiometric modeling approach T Briskot, T Hahn, T Huuk, J Hubbuch Journal of Chromatography A 1653, 462397, 2021 | 25 | 2021 |
| Analysis of complex protein elution behavior in preparative ion exchange processes using a colloidal particle adsorption model T Briskot, T Hahn, T Huuk, G Wang, S Kluters, J Studts, F Wittkopp, ... Journal of Chromatography A 1654, 462439, 2021 | 18 | 2021 |
| Modeling the Gibbs–Donnan effect during ultrafiltration and diafiltration processes using the Poisson–Boltzmann theory in combination with a basic Stern model T Briskot, N Hillebrandt, S Kluters, G Wang, J Studts, T Hahn, T Huuk, ... Journal of Membrane Science 648, 120333, 2022 | 16 | 2022 |
| Adsorption of colloidal proteins in ion-exchange chromatography under consideration of charge regulation T Briskot, T Hahn, T Huuk, J Hubbuch Journal of Chromatography A 1611, 460608, 2020 | 15 | 2020 |
| Deconvolution of high‐throughput multicomponent isotherms using multivariate data analysis of protein spectra P Baumann, T Huuk, T Hahn, A Osberghaus, J Hubbuch Engineering in Life Sciences 16 (2), 194-201, 2016 | 12 | 2016 |
| Modeling of ion-exchange chromatography: Are we making the right assumptions? T Briskot, T Hahn, T Huuk, J Hubbuch ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
| Application of mechanistic modeling to speed up purification process development of novel formats: A virus-like particle case study T Hahn, M Casals, T Huuk, J Wölfel, C Niehus, N Strempel ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
| Risk-based scale-up of high-throughput chromatography systems using Bayesian statistics and mechanistic modeling T Briskot, F Stueckler, K Doninger, F Wittkopp, J Yang, T Hahn, T Huuk, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
| Towards automated model-based process development T Hahn, A Papadopoulos, A Gutzler, T Huuk, T Beck, J Hubbuch ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |
| Modified batch isotherm determination method for mechanistic model calibration T Hahn, T Beck, T Huuk, J Hubbuch ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |
| Model-based quality by design: Challenges, pitfalls and best practices T Huuk, M Casals-Peralvarez, T Hahn, T Beck, J Hubbuch ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |
| Next generation biopharmaceutical process development: Stop experimenting. GoSilico T Huuk, T Beck, T Hahn, J Hubbuch ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |
| When DoE fails: Mechanistic modeling for chromatographic manufacturability T Hahn, T Huuk, T Beck, J Hubbuch ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
| Next generation process development: Stop Experimenting. GoSilico. T Huuk, T Hahn, T Beck, J Hubbuch Simulation 3000, 3500, 2017 | | 2017 |
