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| Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders C Yang, FHG Farias, L Ibanez, A Suhy, B Sadler, MV Fernandez, F Wang, ... Nature neuroscience 24 (9), 1302-1312, 2021 | 134* | 2021 |
| MicroRNA profiling reveals marker of motor neuron disease in ALS models ML Hoye, ED Koval, AJ Wegener, TS Hyman, C Yang, DR O'Brien, ... Journal of Neuroscience 37 (22), 5574-5586, 2017 | 85 | 2017 |
| Cell-type-specific profiling of alternative translation identifies regulated protein isoform variation in the mouse brain D Sapkota, AM Lake, W Yang, C Yang, H Wesseling, A Guise, C Uncu, ... Cell reports 26 (3), 594-607. e7, 2019 | 62 | 2019 |
| The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion Z Li, FHG Farias, U Dube, JL Del-Aguila, KA Mihindukulasuriya, ... Acta neuropathologica 139 (1), 45-61, 2020 | 55 | 2020 |
| Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer’s disease YJ Sung, C Yang, J Norton, M Johnson, A Fagan, RJ Bateman, RJ Perrin, ... Science translational medicine 15 (703), eabq5923, 2023 | 17* | 2023 |
| Quantitative nucleotide level analysis of regulation of translation in response to depolarization of cultured neural cells JS Dalal*, C Yang*, D Sapkota, AM Lake, DR O'Brien, JD Dougherty Frontiers in molecular neuroscience 10, 9, 2017 | 17 | 2017 |
| Mendelian randomization and genetic colocalization infer the effects of the multi-tissue proteome on 211 complex disease-related phenotypes C Yang, AM Fagan, RJ Perrin, H Rhinn, O Harari, C Cruchaga Genome medicine 14 (1), 140, 2022 | 13 | 2022 |
| Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and informs causal proteins for Alzheimer’s disease C Cruchaga, D Western, J Timsina, L Wang, C Wang, C Yang, M Ali, ... Research square, 2023 | 10 | 2023 |
| Large‐scale proteome and metabolome analysis of CSF implicates altered glucose and carbon metabolism and succinylcarnitine in Alzheimer's disease DJ Panyard, J McKetney, YK Deming, AR Morrow, GE Ennis, EM Jonaitis, ... Alzheimer's & Dementia, 2023 | 10* | 2023 |
| Systems biology in the central nervous system: A brief perspective on essential recent advancements JD Dougherty, C Yang, AM Lake Current opinion in systems biology 3, 67-76, 2017 | 9 | 2017 |
| Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease L Ibanez, JA Bahena, C Yang, U Dube, FHG Farias, JP Budde, ... Acta Neuropathologica Communications 8, 1-16, 2020 | 7 | 2020 |
| Proteomic clusters underlie heterogeneity in preclinical Alzheimer’s disease progression JK Wisch, OH Butt, BA Gordon, SE Schindler, AM Fagan, RL Henson, ... Brain 146 (7), 2944-2956, 2023 | 6 | 2023 |
| Proteome wide association studies of LRRK2 variants identify novel causal and druggable proteins for Parkinson’s disease B Phillips, D Western, L Wang, J Timsina, Y Sun, P Gorijala, C Yang, A Do, ... npj Parkinson's Disease 9 (1), 107, 2023 | 5 | 2023 |
| A 3′UTR Insertion Is a Candidate Causal Variant at the TMEM106B Locus Associated With Increased Risk for FTLD-TDP A Chemparathy, Y Le Guen, Y Zeng, J Gorzynski, TD Jensen, C Yang, ... Neurology: Genetics 10 (1), e200124, 2024 | 2 | 2024 |
| Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer’s disease L Wang, NP Nykänen, D Western, P Gorijala, J Timsina, F Li, Z Wang, ... Molecular neurodegeneration 19 (1), 1, 2024 | 1 | 2024 |
| Unique genetic architecture of CSF and brain metabolites pinpoints the novel targets for the traits of human wellness C Wang, D Western, C Yang, M Ali, L Wang, P Gorijala, J Timsina, A Ruiz, ... Research Square, 2023 | 1 | 2023 |
| TOPMed imputed genomics enhances genomic atlas of the human proteome in brain, cerebrospinal fluid, and plasma H Yi, Q Yang, C Repaci, CM Lee, G Heo, J Timsina, P Gorijala, C Yang, ... Scientific Data 11 (1), 387, 2024 | | 2024 |
| Genome-wide study of longitudinal brain imaging measures of multiple sclerosis progression across six clinical trials SJ Loomis, N Sadhu, E Fisher, AR Gafson, Y Huang, C Yang, EE Hughes, ... Scientific Reports 13 (1), 14313, 2023 | | 2023 |
| Genetic analyses of the plasma proteome and metabolome in the same cohort from participants with African and European ancestry identify ancestry‐specific AD risk associated … C Yang, P Gorijala, J Timsina, L Wang, C Wang, E Liu, JC Morris, ... Alzheimer's & Dementia 19, e073687, 2023 | | 2023 |
Carlos CruchagaProfessor. NeuroGenomics and Informatics Center DirectorVerified email at wustl.edu
