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Howard Oliver Fearnhead
Howard Oliver Fearnhead
Lecturer in Pharmacology
Bestätigte E-Mail-Adresse bei nuigalway.ie
Titel
Zitiert von
Zitiert von
Jahr
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13178*2021
Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells
L Faleiro, R Kobayashi, H Fearnhead, Y Lazebnik
The EMBO journal 16 (9), 2271-2281, 1997
4971997
Formation of large molecular weight fragments of DNA is a key committed step of apoptosis in thymocytes.
GM Cohen, XM Sun, H Fearnhead, M MacFarlane, DG Brown, ...
Journal of immunology (Baltimore, Md.: 1950) 153 (2), 507-516, 1994
3101994
Increased membrane permeability of apoptotic thymocytes: a flow cytometric study
MG Ormerod, XM Sun, RT Snowden, R Davies, H Fearnhead, GM Cohen
Cytometry: The Journal of the International Society for Analytical Cytology …, 1993
2441993
Oncogene-dependent apoptosis is mediated by caspase-9
HO Fearnhead, J Rodriguez, EE Govek, W Guo, R Kobayashi, G Hannon, ...
Proceedings of the national academy of sciences 95 (23), 13664-13669, 1998
2191998
An ICE‐like protease is a common mediator of apoptosis induced by diverse stimuli in human monocytic THP. 1 cells
H Zhu, HO Fearnhead, GM Cohen
FEBS letters 374 (2), 303-308, 1995
2071995
A non-apoptotic role for caspase-9 in muscle differentiation
TVA Murray, JM McMahon, BA Howley, A Stanley, T Ritter, A Mohr, ...
Journal of cell science 121 (22), 3786-3793, 2008
1862008
The Apaf‐1• procaspase‐9 apoptosome complex functions as a proteolytic‐based molecular timer
S Malladi, M Challa‐Malladi, HO Fearnhead, SB Bratton
The EMBO journal 28 (13), 1916-1925, 2009
1732009
Molecular Cloning of ILP-2, a Novel Member of the Inhibitor of Apoptosis Protein Family
BWM Richter, SS Mir, LJ Eiben, J Lewis, SB Reffey, A Frattini, L Tian, ...
Molecular and cellular biology 21 (13), 4292-4301, 2001
1592001
Intracellular nucleotides act as critical prosurvival factors by binding to cytochrome C and inhibiting apoptosome
D Chandra, SB Bratton, MD Person, Y Tian, AG Martin, M Ayres, ...
Cell 125 (7), 1333-1346, 2006
1412006
An interleukin-1β-converting enzyme-like protease is a common mediator of apoptosis in thymocytes
HO Fearnhead, D Dinsdale, GM Cohen
FEBS letters 375 (3), 283-288, 1995
1391995
How do we fit ferroptosis in the family of regulated cell death?
HO Fearnhead, P Vandenabeele, T Vanden Berghe
Cell Death & Differentiation 24 (12), 1991-1998, 2017
1342017
New roles for old enzymes: killer caspases as the engine of cell behavior changes
PF Connolly, R Jäger, HO Fearnhead
Frontiers in physiology 5, 79040, 2014
1092014
Caspases as therapeutic targets
B Howley, HO Fearnhead
Journal of cellular and molecular medicine 12 (5a), 1502-1516, 2008
902008
Small molecule inhibitors of Apaf-1-related caspase-3/-9 activation that control mitochondrial-dependent apoptosis
G Malet, AG Martin, M Orzaez, MJ Vicent, I Masip, G Sanclimens, ...
Cell Death & Differentiation 13 (9), 1523-1532, 2006
852006
Oncogene-dependent apoptosis in extracts from drug-resistant cells.
HO Fearnhead, ME McCurrach, J O'Neill, K Zhang, SW Lowe, ...
Genes & development 11 (10), 1266-1276, 1997
841997
Autophagosomal IκBα degradation plays a role in the long term control of tumor necrosis factor-α-induced nuclear factor-κB (NF-κB) activity
A Colleran, A Ryan, A O'Gorman, C Mureau, C Liptrot, P Dockery, ...
Journal of Biological Chemistry 286 (26), 22886-22893, 2011
772011
Cdc2 activation is not required for thymocyte apoptosis
C Norbury, M MacFarlane, H Fearnhead, GM Cohen
Biochemical and biophysical research communications 202 (3), 1400-1406, 1994
751994
A pre‐existing protease is a common effector of thymocyte apoptosis mediated by diverse stimuli
HO Fearnhead, AJ Rivett, D Dinsdale, GM Cohen
FEBS letters 357 (3), 242-246, 1995
661995
Apocytochrome c blocks caspase-9 activation and Bax-induced apoptosis
AG Martin, HO Fearnhead
Journal of Biological Chemistry 277 (52), 50834-50841, 2002
652002
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