David K Breslow
David K Breslow
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Zitiert von
Zitiert von
Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise
JRS Newman, S Ghaemmaghami, J Ihmels, DK Breslow, M Noble, ...
Nature 441 (7095), 840-846, 2006
Orm family proteins mediate sphingolipid homeostasis
DK Breslow, SR Collins, B Bodenmiller, R Aebersold, K Simons, ...
Nature 463 (7284), 1048-1053, 2010
A comprehensive strategy enabling high-resolution functional analysis of the yeast genome
DK Breslow, DM Cameron, SR Collins, M Schuldiner, J Stewart-Ornstein, ...
Nature methods 5 (8), 711-718, 2008
Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae
FM Roelants, DK Breslow, A Muir, JS Weissman, J Thorner
Proceedings of the National Academy of Sciences 108 (48), 19222-19227, 2011
Membranes in balance: mechanisms of sphingolipid homeostasis
DK Breslow, JS Weissman
Molecular cell 40 (2), 267-279, 2010
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
S Seo, Q Zhang, K Bugge, DK Breslow, CC Searby, MV Nachury, ...
PLoS genetics 7 (11), e1002358, 2011
The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3
GM Liew, F Ye, AR Nager, JP Murphy, JS Lee, M Aguiar, DK Breslow, ...
Developmental cell 31 (3), 265-278, 2014
An in vitro assay for entry into cilia reveals unique properties of the soluble diffusion barrier
DK Breslow, EF Koslover, F Seydel, AJ Spakowitz, MV Nachury
Journal of Cell Biology 203 (1), 129-147, 2013
Mechanism and regulation of centriole and cilium biogenesis
DK Breslow, AJ Holland
Annual review of biochemistry 88, 691-724, 2019
A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies
DK Breslow, S Hoogendoorn, AR Kopp, DW Morgens, BK Vu, ...
Nature genetics 50 (3), 460-471, 2018
Single molecule imaging reveals a major role for diffusion in the exploration of ciliary space by signaling receptors
F Ye, DK Breslow, EF Koslover, AJ Spakowitz, WJ Nelson, MV Nachury
Elife 2, e00654, 2013
Sphingolipid homeostasis in the endoplasmic reticulum and beyond
DK Breslow
Cold Spring Harbor perspectives in biology 5 (4), a013326, 2013
Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway
AK Ganga, MC Kennedy, ME Oguchi, S Gray, KE Oliver, TA Knight, ...
Current Biology 31 (13), 2895-2905. e7, 2021
Primary cilia: how to keep the riff-raff in the plasma membrane
DK Breslow, MV Nachury
Current Biology 21 (11), R434-R436, 2011
Analysis of soluble protein entry into primary cilia using semipermeabilized cells
DK Breslow, MV Nachury
Methods in cell biology 127, 203-221, 2015
Rab34 GTPase mediates ciliary membrane biogenesis in the intracellular ciliogenesis pathway
AK Ganga, MC Kennedy, ME Oguchi, SD Gray, KE Oliver, TA Knight, ...
bioRxiv, 2020.10. 29.360891, 2020
A comprehensive portrait of cilia and ciliopathies from a CRISPR-based screen for hedgehog signaling
DK Breslow, S Hoogendoorn, AR Kopp, DW Morgens, BK Vu, K Han, A Li, ...
bioRxiv, 156059, 2017
Pathogenic RAB34 variants impair primary cilium assembly and cause a novel oral-facial-digital syndrome
AL Bruel, AK Ganga, L Nosková, I Valenzuela, J Martinovic, Y Duffourd, ...
Human Molecular Genetics 32 (18), 2822-2831, 2023
Pericentrin Knocks Down Cilia in Trisomy 21
DK Breslow
Developmental Cell 46 (5), 527-528, 2018
Development of a High-Resolution Growth Assay for Yeast Functional Genomics and Identification of Orm Family Proteins as Key Mediators of Sphingolipid Homeostasis
DK Breslow
UCSF, 2010
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