Leona Plum-Mörschel (Plum)
Leona Plum-Mörschel (Plum)
CEO, Profil (Mainz)
Verified email at profil.com - Homepage
Cited by
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Agouti-related peptide–expressing neurons are mandatory for feeding
E Gropp, M Shanabrough, E Borok, AW Xu, R Janoschek, T Buch, L Plum, ...
Nature neuroscience 8 (10), 1289-1291, 2005
The role of insulin receptor signaling in the brain
L Plum, M Schubert, JC Brüning
Trends in Endocrinology & Metabolism 16 (2), 59-65, 2005
Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production
AC Könner, R Janoschek, L Plum, SD Jordan, E Rother, X Ma, C Xu, ...
Cell metabolism 5 (6), 438-449, 2007
A guide to analysis of mouse energy metabolism
MH Tschöp, JR Speakman, JRS Arch, J Auwerx, JC Brüning, L Chan, ...
Nature methods 9 (1), 57-63, 2012
Central insulin action in energy and glucose homeostasis
L Plum, BF Belgardt, JC Brüning
The Journal of clinical investigation 116 (7), 1761-1766, 2006
Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity
L Plum, X Ma, B Hampel, N Balthasar, R Coppari, H Münzberg, ...
The Journal of clinical investigation 116 (7), 1886-1901, 2006
W Becker, R Kluge, T Kantner, K Linnartz, M Korn, G Tschank, L Plum, ...
Effect of the sodium glucose co‐transporter 2 inhibitor canagliflozin on plasma volume in patients with type 2 diabetes mellitus
S Sha, D Polidori, T Heise, J Natarajan, K Farrell, SS Wang, D Sica, ...
Diabetes, Obesity and Metabolism 16 (11), 1087-1095, 2014
The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake
L Plum, HV Lin, R Dutia, J Tanaka, KS Aizawa, M Matsumoto, AJ Kim, ...
Nature medicine 15 (10), 1195-1201, 2009
Peripheral hyperinsulinemia promotes tau phosphorylation in vivo
S Freude, L Plum, J Schnitker, U Leeser, M Udelhoven, W Krone, ...
Diabetes 54 (12), 3343-3348, 2005
Divergent regulation of energy expenditure and hepatic glucose production by insulin receptor in agouti-related protein and POMC neurons
HV Lin, L Plum, H Ono, R Gutiérrez-Juárez, M Shanabrough, E Borok, ...
Diabetes 59 (2), 337-346, 2010
FoxO1 target Gpr17 activates AgRP neurons to regulate food intake
H Ren, IJ Orozco, Y Su, S Suyama, R Gutiérrez-Juárez, TL Horvath, ...
Cell 149 (6), 1314-1326, 2012
Enhanced leptin-stimulated Pi3k activation in the CNS promotes white adipose tissue transdifferentiation
L Plum, E Rother, H Münzberg, FT Wunderlich, DA Morgan, B Hampel, ...
Cell metabolism 6 (6), 431-445, 2007
Single copy shRNA configuration for ubiquitous gene knockdown in mice
J Seibler, B Küter-Luks, H Kern, S Streu, L Plum, J Mauer, R Kühn, ...
Nucleic acids research 33 (7), e67-e67, 2005
MEDI0382, a GLP-1 and glucagon receptor dual agonist, in obese or overweight patients with type 2 diabetes: a randomised, controlled, double-blind, ascending dose and phase 2a …
P Ambery, VE Parker, M Stumvoll, MG Posch, T Heise, L Plum-Moerschel, ...
The Lancet 391 (10140), 2607-2618, 2018
Myeloid cell-restricted insulin receptor deficiency protects against obesity-induced inflammation and systemic insulin resistance
J Mauer, B Chaurasia, L Plum, T Quast, B Hampel, M Blüher, W Kolanus, ...
PLoS Genet 6 (5), e1000938, 2010
A metabolic syndrome of hypertension, hyperinsulinaemia and hypercholesterolaemia in the New Zealand obese mouse.
JR Ortlepp, R Kluge, K Giesen, L Plum, P Radke, P Hanrath, HG Joost
European journal of clinical investigation 30 (3), 195, 2000
Validation of a novel method for determining the renal threshold for glucose excretion in untreated and canagliflozin-treated subjects with type 2 diabetes mellitus
D Polidori, S Sha, A Ghosh, L Plum-Mörschel, T Heise, P Rothenberg
The Journal of Clinical Endocrinology & Metabolism 98 (5), E867-E871, 2013
Comparison of glucostatic parameters after hypocaloric diet or bariatric surgery and equivalent weight loss
L Plum, L Ahmed, G Febres, M Bessler, W Inabnet, E Kunreuther, ...
Obesity 19 (11), 2149-2157, 2011
Pharmacodynamic differences between canagliflozin and dapagliflozin: results of a randomized, double‐blind, crossover study
S Sha, D Polidori, K Farrell, A Ghosh, J Natarajan, N Vaccaro, J Pinheiro, ...
Diabetes, Obesity and Metabolism 17 (2), 188-197, 2015
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