| Transcription-independent pro-apoptotic functions of p53 UM Moll, S Wolff, D Speidel, W Deppert Current opinion in cell biology 17 (6), 631-636, 2005 | 654 | 2005 |
| Transcription-independent p53 apoptosis: an alternative route to death D Speidel Trends in cell biology 20 (1), 14-24, 2010 | 412 | 2010 |
| Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells M Michaelis, F Rothweiler, S Barth, J Cinatl, M Van Rikxoort, ... Cell death & disease 2 (12), e243-e243, 2011 | 184 | 2011 |
| The role of DNA damage responses in p53 biology D Speidel Archives of toxicology 89 (4), 501-517, 2015 | 181 | 2015 |
| Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells EL Kim, R Wüstenberg, A Rübsam, C Schmitz-Salue, G Warnecke, ... Neuro-oncology 12 (4), 389-400, 2010 | 174 | 2010 |
| Dissection of transcriptional and non-transcriptional p53 activities in the response to genotoxic stress D Speidel, H Helmbold, W Deppert Oncogene 25 (6), 940-953, 2006 | 95 | 2006 |
| Inhibition of casein kinase I delta alters mitotic spindle formation and induces apoptosis in trophoblast cells M Stöter, AM Bamberger, B Aslan, M Kurth, D Speidel, T Löning, ... Oncogene 24 (54), 7964-7975, 2005 | 91 | 2005 |
| Mutant p53R270H gain of function phenotype in a mouse model for oncogene‐induced mammary carcinogenesis C Heinlein, F Krepulat, J Löhler, D Speidel, W Deppert, GV Tolstonog International journal of cancer 122 (8), 1701-1709, 2008 | 84 | 2008 |
| Gadd45β is a pro-survival factor associated with stress-resistant tumors A Engelmann, D Speidel, GW Bornkamm, W Deppert, C Stocking Oncogene 27 (10), 1429-1438, 2008 | 45 | 2008 |
| Mutations in SIPA1L3 cause eye defects through disruption of cell polarity and cytoskeleton organization R Greenlees, M Mihelec, S Yousoof, D Speidel, SK Wu, S Rinkwitz, ... Human molecular genetics 24 (20), 5789-5804, 2015 | 41 | 2015 |
| A rapid and optimization-free procedure allows the in vivo detection of subtle cell cycle and ploidy alterations in tissues by flow cytometry C Heinlein, W Deppert, A Braithwaite, D Speidel Cell Cycle 9 (17), 3584-3590, 2010 | 35 | 2010 |
| Human neuroblastoma cells with acquired resistance to the p53 activator RITA retain functional p53 and sensitivity to other p53 activating agents M Michaelis, F Rothweiler, B Agha, S Barth, Y Voges, N Löschmann, ... Cell death & disease 3 (4), e294-e294, 2012 | 34 | 2012 |
| HOXB4 inhibits cell growth in a dose-dependent manner and sensitizes cells towards extrinsic cues E Will, D Speidel, Z Wang, G Ghiaur, A Rimek, B Schiedlmeier, ... Cell cycle 5 (1), 14-22, 2006 | 31 | 2006 |
| Cellular stress responses in cancer and cancer therapy M Chircop, D Speidel Frontiers in oncology 4, 304, 2014 | 27 | 2014 |
| Δ122p53, a mouse model of Δ133p53α, enhances the tumor-suppressor activities of an attenuated p53 mutant TL Slatter, N Hung, S Bowie, H Campbell, C Rubio, D Speidel, M Wilson, ... Cell death & disease 6 (6), e1783-e1783, 2015 | 26 | 2015 |
| Resistance acquisition to MDM2 inhibitors J Cinatl, D Speidel, I Hardcastle, M Michaelis Biochemical Society transactions 42 (4), 752-757, 2014 | 25 | 2014 |
| RUNX1 upregulation by cytotoxic drugs promotes apoptosis D Speidel, J Wellbrock, M Abas Cancer Research 77 (24), 6818-6824, 2017 | 10 | 2017 |
| High‐resolution cell cycle and DNA ploidy analysis in tissue samples C Heinlein, D Speidel Current protocols in cytometry 56 (1), 7.39. 1-7.39. 11, 2011 | 9 | 2011 |
| TP53 mutations and drug sensitivity in acute myeloid leukaemia cells with acquired MDM2 inhibitor resistance M Michaelis, C Schneider, F Rothweiler, T Rothenburger, M Mernberger, ... bioRxiv, 404475, 2018 | 3 | 2018 |
| Molecular mechanisms of cellular stress responses in cancer and their therapeutic implications M Chircop, D Speidel Frontiers Media SA, 2015 | 2 | 2015 |
Thorsten StieweVerified email at staff.uni-marburg.de
