Euan Stronach
Euan Stronach
Bestätigte E-Mail-Adresse bei gsk.com
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Zitiert von
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Rethinking ovarian cancer: recommendations for improving outcomes
S Vaughan, JI Coward, RC Bast, A Berchuck, JS Berek, JD Brenton, ...
Nature Reviews Cancer 11 (10), 719-725, 2011
11662011
Whole–genome characterization of chemoresistant ovarian cancer
AM Patch, EL Christie, D Etemadmoghadam, DW Garsed, J George, ...
Nature 521 (7553), 489-494, 2015
9632015
Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer
DD Bowtell, S Böhm, AA Ahmed, PJ Aspuria, RC Bast, V Beral, JS Berek, ...
Nature reviews Cancer 15 (11), 668-679, 2015
6692015
Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens
FM Behan, F Iorio, G Picco, E Gonçalves, CM Beaver, G Migliardi, ...
Nature 568 (7753), 511-516, 2019
3362019
OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer
GC Sellar, KP Watt, GJ Rabiasz, EA Stronach, L Li, EP Miller, CE Massie, ...
Nature genetics 34 (3), 337-343, 2003
2232003
HDAC4-regulated STAT1 activation mediates platinum resistance in ovarian cancer
EA Stronach, A Alfraidi, N Rama, C Datler, JB Studd, R Agarwal, ...
Cancer research 71 (13), 4412-4422, 2011
1542011
DNA-PK mediates AKT activation and apoptosis inhibition in clinically acquired platinum resistance
EA Stronach, M Chen, EN Maginn, R Agarwal, GB Mills, H Wasan, ...
Neoplasia 13 (11), 1069-IN35, 2011
1282011
Oxidative metabolism drives inflammation-induced platinum resistance in human ovarian cancer
DS Matassa, MR Amoroso, H Lu, R Avolio, D Arzeni, C Procaccini, ...
Cell Death & Differentiation 23 (9), 1542-1554, 2016
972016
Systematic CpG islands methylation profiling of genes in the wnt pathway in epithelial ovarian cancer identifies biomarkers of progression-free survival
W Dai, JM Teodoridis, C Zeller, J Graham, J Hersey, JM Flanagan, ...
Clinical Cancer Research 17 (12), 4052-4062, 2011
862011
Microarray coupled to quantitative RT–PCR analysis of androgen-regulated genes in human LNCaP prostate cancer cells
S Ngan, EA Stronach, A Photiou, J Waxman, S Ali, L Buluwela
Oncogene 28 (19), 2051-2063, 2009
842009
Comparing the characteristics of gene expression profiles derived by univariate and multivariate classification methods
M Zucknick, S Richardson, EA Stronach
Statistical applications in genetics and molecular biology 7 (1), 2008
782008
Chromatin H3K27me3/H3K4me3 histone marks define gene sets in high-grade serous ovarian cancer that distinguish malignant, tumour-sustaining and chemo-resistant ovarian tumour cells
N Chapman-Rothe, E Curry, C Zeller, D Liber, E Stronach, H Gabra, ...
Oncogene 32 (38), 4586-4592, 2013
722013
BARX2 induces cadherin 6 expression and is a functional suppressor of ovarian cancer progression
GC Sellar, L Li, KP Watt, BD Nelkin, GJ Rabiasz, EA Stronach, EP Miller, ...
Cancer research 61 (19), 6977-6981, 2001
592001
MicroRNAs associated with small bowel neuroendocrine tumours and their metastases
HC Miller, AE Frampton, A Malczewska, S Ottaviani, EA Stronach, R Flora, ...
Endocr Relat Cancer 23 (9), 711-726, 2016
492016
Novel PCR-based diagnostic tools for Charcot-Marie-Tooth type 1A and hereditary neuropathy with liability to pressure palsies.
EA Stronach, C Clark, C Bell, A Löfgren, NG McKay, V Timmerman, ...
Journal of the peripheral nervous system: JPNS 4 (2), 117-122, 1999
481999
Identification of clinically relevant genes on chromosome 11 in a functional model of ovarian cancer tumor suppression
EA Stronach, GC Sellar, C Blenkiron, GJ Rabiasz, KJ Taylor, EP Miller, ...
Cancer research 63 (24), 8648-8655, 2003
432003
The role of interleukin-8 (IL-8) and IL-8 receptors in platinum response in high grade serous ovarian carcinoma
EA Stronach, P Cunnea, C Turner, T Guney, R Aiyappa, S Jeyapalan, ...
Oncotarget 6 (31), 31593, 2015
402015
Unsupervised correction of gene-independent cell responses to CRISPR-Cas9 targeting
F Iorio, FM Behan, E Gonçalves, SG Bhosle, E Chen, R Shepherd, ...
BMC genomics 19 (1), 1-16, 2018
392018
Biomarker assessment of HR deficiency, tumor BRCA1/2 mutations, and CCNE1 copy number in ovarian cancer: associations with clinical outcome following platinum monotherapy
EA Stronach, J Paul, KM Timms, E Hughes, K Brown, C Neff, M Perry, ...
Molecular Cancer Research 16 (7), 1103-1111, 2018
352018
Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screening
G Picco, ED Chen, LG Alonso, FM Behan, E Gonçalves, G Bignell, ...
Nature communications 10 (1), 1-12, 2019
342019
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