Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms F Berger, C Lau, M Dahlmann, M Ziegler Journal of Biological Chemistry 280 (43), 36334-36341, 2005 | 581 | 2005 |
The NMN/NaMN adenylyltransferase (NMNAT) protein family C Lau, M Niere, M Ziegler Front Biosci 14, 410-431, 2009 | 148 | 2009 |
Regulation of poly (ADP-ribose) polymerase 1 activity by the phosphorylation state of the nuclear NAD biosynthetic enzyme NMN adenylyl transferase 1 F Berger, C Lau, M Ziegler Proceedings of the National Academy of Sciences 104 (10), 3765-3770, 2007 | 137 | 2007 |
Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn RF Hallstensen, G Bergseth, S Foss, S Jæger, T Gedde-Dahl, J Holt, ... Immunobiology 220 (4), 452-459, 2015 | 116 | 2015 |
Isoform-specific targeting and interaction domains in human nicotinamide mononucleotide adenylyltransferases C Lau, C Dölle, TI Gossmann, L Agledal, M Niere, M Ziegler Journal of biological chemistry 285 (24), 18868-18876, 2010 | 83 | 2010 |
Chimeric anti-CD14 IGG2/4 hybrid antibodies for therapeutic intervention in pig and human models of inflammation C Lau, KS Gunnarsen, LS Høydahl, JT Andersen, G Berntzen, A Pharo, ... The Journal of Immunology 191 (9), 4769-4777, 2013 | 56 | 2013 |
Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis EW Skjeflo, C Sagatun, K Dybwik, S Aam, SH Urving, MA Nunn, H Fure, ... Critical Care 19, 1-8, 2015 | 41 | 2015 |
Development of β-amino alcohol derivatives that inhibit Toll-like receptor 4 mediated inflammatory response as potential antiseptics SA Chavez, AJ Martinko, C Lau, MN Pham, K Cheng, DE Bevan, ... Journal of medicinal chemistry 54 (13), 4659-4669, 2011 | 40 | 2011 |
Complement component C5 and TLR molecule CD14 mediate heme-induced thromboinflammation in human blood AM Thomas, A Gerogianni, MB McAdam, Y Fløisand, C Lau, T Espevik, ... The Journal of Immunology 203 (6), 1571-1578, 2019 | 35 | 2019 |
CD14 and Complement Crosstalk and Largely Mediate the Transcriptional Response to Escherichia coli in Human Whole Blood as Revealed by DNA Microarray C Lau, S Nygård, H Fure, OK Olstad, M Holden, KT Lappegård, OL Brekke, ... PLoS One 10 (2), e0117261, 2015 | 27 | 2015 |
Combined inhibition of complement and CD14 attenuates bacteria-induced inflammation in human whole blood more efficiently than antagonizing the Toll-like receptor 4–MD2 complex A Gustavsen, S Nymo, A Landsem, D Christiansen, L Ryan, H Husebye, ... The Journal of infectious diseases 214 (1), 140-150, 2016 | 25 | 2016 |
Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis BC Hellerud, HL Orrem, K Dybwik, SE Pischke, A Baratt-Due, ... Journal of Intensive Care 5, 1-9, 2017 | 20 | 2017 |
Human endothelial cell activation by Escherichia coli and Staphylococcus aureus is mediated by TNF and IL-1β secondarily to activation of C5 and CD14 in whole blood S Nymo, A Gustavsen, PH Nilsson, C Lau, T Espevik, TE Mollnes The Journal of Immunology 196 (5), 2293-2299, 2016 | 18 | 2016 |
The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load KH Egge, A Barratt-Due, S Nymo, JK Lindstad, A Pharo, C Lau, T Espevik, ... Clinical & Experimental Immunology 181 (3), 457-467, 2015 | 14 | 2015 |
Simultaneous C5 and CD14 inhibition limits inflammation and organ dysfunction in pig polytrauma L Lupu, K Horst, J Greven, Ü Mert, JAK Ludviksen, K Pettersen, C Lau, ... Frontiers in Immunology 13, 952267, 2022 | 10 | 2022 |
Combined inhibition of C5 and CD14 attenuates systemic inflammation in a piglet model of meconium aspiration syndrome AM Thomas, C Schjalm, PH Nilsson, PHH Lindenskov, R Rørtveit, ... Neonatology 113 (4), 322-330, 2018 | 10 | 2018 |
Air bubbles activate complement and trigger hemostasis and C3-Dependent cytokine release ex vivo in human whole blood BS Storm, D Christiansen, H Fure, JK Ludviksen, C Lau, JD Lambris, ... The Journal of Immunology 207 (11), 2828-2840, 2021 | 9 | 2021 |
Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like … A Landsem, H Fure, J Krey Ludviksen, D Christiansen, C Lau, M Mathisen, ... Clinical & Experimental Immunology 196 (1), 97-110, 2019 | 7 | 2019 |
Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response C Lau, OK Olstad, M Holden, S Nygård, H Fure, KT Lappegård, OL Brekke, ... Genomics Data 5, 176-183, 2015 | 7 | 2015 |
Complement C3b contributes to Escherichia coli-induced platelet aggregation in human whole blood A Landsem, Å Emblem, C Lau, D Christiansen, A Gerogianni, BO Karlsen, ... Frontiers in Immunology 13, 1020712, 2022 | 5 | 2022 |