| Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis S Chen, NE Sanjana, K Zheng, O Shalem, K Lee, X Shi, DA Scott, J Song, ... Cell 160 (6), 1246-1260, 2015 | 1053 | 2015 |
| Characterizing sleep spindles in 11,630 individuals from the National Sleep Research Resource SM Purcell, DS Manoach, C Demanuele, BE Cade, S Mariani, R Cox, ... Nature communications 8 (1), 15930, 2017 | 362 | 2017 |
| Reduced sleep spindles in schizophrenia: a treatable endophenotype that links risk genes to impaired cognition? DS Manoach, JQ Pan, SM Purcell, R Stickgold Biological psychiatry 80 (8), 599-608, 2016 | 222 | 2016 |
| Functional implications of a psychiatric risk variant within CACNA1C in induced human neurons T Yoshimizu, JQ Pan, AE Mungenast, JM Madison, S Su, J Ketterman, ... Molecular psychiatry 20 (2), 162-169, 2015 | 174 | 2015 |
| Functional diversity in neuronal voltage-gated calcium channels by alternative splicing of Cavα1 D Lipscombe, JQ Pan, AC Gray Molecular neurobiology 26, 21-44, 2002 | 143 | 2002 |
| AKT kinase activity is required for lithium to modulate mood-related behaviors in mice JQ Pan, MC Lewis, JK Ketterman, EL Clore, M Riley, KR Richards, ... Neuropsychopharmacology 36 (7), 1397-1411, 2011 | 132 | 2011 |
| Alternative splicing of a short cassette exon in α1B generates functionally distinct N-type calcium channels in central and peripheral neurons Z Lin, Y Lin, S Schorge, JQ Pan, M Beierlein, D Lipscombe Journal of Neuroscience 19 (13), 5322-5331, 1999 | 124 | 1999 |
| Comprehensive comparative analysis of 5′-end RNA-sequencing methods X Adiconis, AL Haber, SK Simmons, A Levy Moonshine, Z Ji, MA Busby, ... Nature methods 15 (7), 505-511, 2018 | 106 | 2018 |
| Regulation of N-type voltage-gated calcium channels and presynaptic function by cyclin-dependent kinase 5 SC Su, J Seo, JQ Pan, BA Samuels, A Rudenko, M Ericsson, RL Neve, ... Neuron 75 (4), 675-687, 2012 | 101 | 2012 |
| Pharmacological activation and inhibition of Slack (Slo2. 2) channels B Yang, VK Gribkoff, J Pan, V Damagnez, SI Dworetzky, CG Boissard, ... Neuropharmacology 51 (4), 896-906, 2006 | 99 | 2006 |
| Predicting functional effects of missense variants in voltage-gated sodium and calcium channels HO Heyne, D Baez-Nieto, S Iqbal, DS Palmer, A Brunklaus, P May, ... Science translational medicine 12 (556), eaay6848, 2020 | 98 | 2020 |
| Use-dependent blockade of Cav2. 2 voltage-gated calcium channels for neuropathic pain RJ Winquist, JQ Pan, VK Gribkoff Biochemical pharmacology 70 (4), 489-499, 2005 | 98 | 2005 |
| Alternative splicing in the cytoplasmic II–III loop of the N-type Ca channel α1B subunit: functional differences are β subunit-specific JQ Pan, D Lipscombe Journal of Neuroscience 20 (13), 4769-4775, 2000 | 94 | 2000 |
| Effects of 3D culturing conditions on the transcriptomic profile of stem-cell-derived neurons H Tekin, S Simmons, B Cummings, L Gao, X Adiconis, CC Hession, ... Nature Biomedical Engineering 2 (7), 540-554, 2018 | 90 | 2018 |
| Exploiting an Asp-Glu “switch” in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia FF Wagner, L Benajiba, AJ Campbell, M Weïwer, JR Sacher, JP Gale, ... Science translational medicine 10 (431), eaam8460, 2018 | 85 | 2018 |
| Biological concepts in human sodium channel epilepsies and their relevance in clinical practice A Brunklaus, J Du, F Steckler, II Ghanty, KM Johannesen, CD Fenger, ... Epilepsia 61 (3), 387-399, 2020 | 75 | 2020 |
| A rare schizophrenia risk variant of CACNA1I disrupts CaV3.3 channel activity A Andrade, J Hope, A Allen, V Yorgan, D Lipscombe, JQ Pan Scientific reports 6 (1), 34233, 2016 | 70 | 2016 |
| Discovery of potent and highly selective inhibitors of GSK3b WF An, AR Germain, JA Bishop, PP Nag, S Metkar, J Ketterman, M Walk, ... Probe Reports from the NIH Molecular Libraries Program [Internet], 2014 | 60 | 2014 |
| Inhibitors of glycogen synthase kinase 3 with exquisite kinome-wide selectivity and their functional effects FF Wagner, JA Bishop, JP Gale, X Shi, M Walk, J Ketterman, D Patnaik, ... ACS Chemical Biology 11 (7), 1952-1963, 2016 | 56 | 2016 |
| Selective inhibition of glycogen synthase kinase 3α corrects pathophysiology in a mouse model of fragile X syndrome PK McCamphill, LJ Stoppel, RK Senter, MC Lewis, AJ Heynen, ... Science translational medicine 12 (544), eaam8572, 2020 | 47 | 2020 |
