Allosteric ACTion: the varied ACT domains regulating enzymes of amino-acid metabolism EJM Lang, PJ Cross, G Mittelstädt, GB Jameson, EJ Parker Current opinion in structural biology 29, 102-111, 2014 | 84 | 2014 |
De Novo-Designed α-Helical Barrels as Receptors for Small Molecules F Thomas, WM Dawson, EJM Lang, AJ Burton, GJ Bartlett, GG Rhys, ... ACS Synthetic Biology 7 (7), 1808-1816, 2018 | 72 | 2018 |
Constructing ion channels from water-soluble α-helical barrels AJ Scott, A Niitsu, HT Kratochvil, EJM Lang, JT Sengel, WM Dawson, ... Nature chemistry 13 (7), 643-650, 2021 | 67 | 2021 |
Maintaining and breaking symmetry in homomeric coiled-coil assemblies GG Rhys, CW Wood, EJM Lang, AJ Mulholland, RL Brady, AR Thomson, ... Nature communications 9 (1), 4132, 2018 | 60 | 2018 |
Structural resolution of switchable states of a de novo peptide assembly WM Dawson, EJM Lang, GG Rhys, KL Shelley, C Williams, RL Brady, ... Nature Communications 12 (1), 1530, 2021 | 23 | 2021 |
Interdomain Conformational Changes Provide Allosteric Regulation en Route to Chorismate*♦ AR Nazmi, EJM Lang, Y Bai, TM Allison, MH Othman, S Panjikar, ... Journal of Biological Chemistry 291 (42), 21836-21847, 2016 | 23 | 2016 |
Calculated pKa Variations Expose Dynamic Allosteric Communication Networks EJM Lang, LC Heyes, GB Jameson, EJ Parker Journal of the American Chemical Society 138 (6), 2036-2045, 2016 | 23 | 2016 |
Structural and functional characterisation of the entry point to pyocyanin biosynthesis in Pseudomonas aeruginosa defines a new 3-deoxy-d-arabino-heptulosonate 7-phosphate … OW Sterritt, EJM Lang, SA Kessans, TM Ryan, B Demeler, GB Jameson, ... Bioscience Reports 38 (5), BSR20181605, 2018 | 17 | 2018 |
Generalized Born Implicit Solvent Models Do Not Reproduce Secondary Structures of De Novo Designed Glu/Lys Peptides EJM Lang, EG Baker, DN Woolfson, AJ Mulholland Journal of chemical theory and computation 18 (7), 4070-4076, 2022 | 14 | 2022 |
Resistance to the “last resort” antibiotic colistin: a single-zinc mechanism for phosphointermediate formation in MCR enzymes E Lythell, R Suardíaz, P Hinchliffe, C Hanpaibool, S Visitsatthawong, ... Chemical communications 56 (50), 6874-6877, 2020 | 13 | 2020 |
Multiscale workflow for modeling ligand complexes of zinc metalloproteins Z Yang, RM Twidale, S Gervasoni, R Suardíaz, CK Colenso, EJM Lang, ... Journal of Chemical Information and Modeling 61 (11), 5658-5672, 2021 | 12 | 2021 |
Industrial applications of chiral chromatography J Bléhaut, P Franco, T Zhang, E Lang, E Valéry, JF Marcoux Reference module in chemistry, molecular sciences and chemical engineering …, 2012 | 12* | 2012 |
Diverse allosteric componentry and mechanisms control entry into aromatic metabolite biosynthesis W Jiao, EJM Lang, Y Bai, Y Fan, EJ Parker Current Opinion in Structural Biology 65, 159-167, 2020 | 10 | 2020 |
Domain cross-talk within a bifunctional enzyme provides catalytic and allosteric functionality in the biosynthesis of aromatic amino acids Y Bai, EJM Lang, AR Nazmi, EJ Parker Journal of Biological Chemistry 294 (13), 4828-4842, 2019 | 9 | 2019 |
Preparative and Industrial Scale Chromatography: Green and Integrated Processes E Lang, E Valéry, O Ludemann-Hombourger, W Majewski, J Bléhaut Green Chemistry in the Pharmaceutical Industry, 243-268, 2010 | 3 | 2010 |
Molecular Dynamics, Quantum Mechanics, and Combined Quantum Mechanics/Molecular Mechanics Methods for Drug Discovery and Development EJM Lang, AJ Mulholland Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, 2017 | 1 | 2017 |
Implicit solvent models fail to reproduce secondary structures of de novo designed peptides E Lang, E Baker, D Woolfson, A Mulholland | | 2021 |
Automated Peptide Synthesis E Lang, J Blehaut ChemInform 40 (40), no-no, 2009 | | 2009 |