The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases S Krasemann, C Madore, R Cialic, C Baufeld, N Calcagno, R El Fatimy, ... Immunity 47 (3), 566-581. e9, 2017 | 796 | 2017 |
Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development JFP Berbée, MR Boon, PPSJ Khedoe, A Bartelt, C Schlein, A Worthmann, ... Nature communications 6 (1), 1-11, 2015 | 274 | 2015 |
Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis A Worthmann, C John, MC Rühlemann, M Baguhl, FA Heinsen, ... Nature medicine 23 (7), 839, 2017 | 126 | 2017 |
Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport A Bartelt, C John, N Schaltenberg, JFP Berbée, A Worthmann, ... Nature communications 8 (1), 1-10, 2017 | 68 | 2017 |
Metabolic circuit involving free fatty acids, microRNA 122, and triglyceride synthesis in liver and muscle tissues C Chai, M Rivkin, L Berkovits, A Simerzin, E Zorde-Khvalevsky, ... Gastroenterology 153 (5), 1404-1415, 2017 | 43 | 2017 |
A liquid chromatography-tandem mass spectrometry-based method for the simultaneous determination of hydroxy sterols and bile acids C John, P Werner, A Worthmann, K Wegner, K Tödter, L Scheja, S Rohn, ... Journal of Chromatography A 1371, 184-195, 2014 | 43 | 2014 |
Effects of Pharmacological Thermogenic Adipocyte Activation on Metabolism and Atherosclerotic Plaque Regression A Worthmann, C Schlein, JFP Berbée, PCN Rensen, J Heeren, A Bartelt Nutrients 11 (2), 463, 2019 | 3 | 2019 |
Inulin Supplementation Disturbs Hepatic Cholesterol and Bile Acid Metabolism Independent from Housing Temperature MJ Pauly, JK Rohde, C John, I Evangelakos, AC Koop, P Pertzborn, ... Nutrients 12 (10), 3200, 2020 | 2 | 2020 |
Characterization of Genetic and Metabolic Somatic Events in Aortic Atherosclerotic Plaques TJ Demal, A Worthmann, H Reichenspurner, C Detter, J Heeren, ... The Thoracic and Cardiovascular Surgeon 69 (S 01), DGTHG-KV35, 2021 | | 2021 |
Endothelial lipase is involved in cold-induced HDL turnover and reverse cholesterol transport in mice N Schaltenberg, C John, M Heine, F Haumann, F Rinninger, L Scheja, ... Frontiers in Cardiovascular Medicine 8, 90, 2021 | | 2021 |
Lysosomal lipoprotein processing in endothelial cells stimulates adipose tissue thermogenic adaptation AW Fischer, MY Jaeckstein, K Gottschling, M Heine, F Sass, N Mangels, ... Cell Metabolism, 2020 | | 2020 |
The role of the CYP7B1-derived cholesterol metabolites in nash development I Evangelakos, A Worthmann, C John, L Scheja, J Heeren Atherosclerosis 315, e11, 2020 | | 2020 |
TREM2-Positive Lipid-Associated Macrophages (LAMs) Control White Adipose Tissue Remodeling and Metabolic Adaptation in Obesity A Worthmann, J Heeren Immunometabolism 2 (2), 2020 | | 2020 |
Increased hepatic bile acid production shapes the gut microbiome after cold induced brown adipose tissue activation A Worthmann, C John, MC Rühlemann, M Baguhl, C Schlein, FA Heinsen, ... Atherosclerosis 275, e15, 2018 | | 2018 |
Assessment of Uptake and Biodistribution of Radiolabeled Cholesterol in Mice Using Gavaged Recombinant Triglyceride-rich Lipoprotein Particles (rTRL) A Worthmann, C John, J Heeren Bio-protocol 8 (13), e2916-e2916, 2018 | | 2018 |
Brown and beige adipocyte activity controls metabolic flux through the HDL compartment N Schaltenberg, A Bartelt, J Clara, A Worthmann, CM Lisa, R Franz, ... Atherosclerosis 252, e237, 2016 | | 2016 |
LC-ESI-MS/MS method for the simultaneous determination of hydroxysterols and bile acids in different biological matrices: 149/381. S Rohn, K Wegner, P Werner, C John, A Worthmann, L Scheja, J Heeren, ... Annals of Nutrition and Metabolism 67, 2015 | | 2015 |
LC-MS/MS-Multi Methods for the Quantification of Hydroxysterols and Bile Acids from biological Matrices P Werner, K Wegner, C John, A Worthmann, L Scheja, J Heeren, S Rohn, ... DEUTSCHE LEBENSMITTEL-RUNDSCHAU 111 (5), 198-203, 2015 | | 2015 |
Linking white-to-brown fat remodeling to fatty acid and lipoprotein metabolism L Scheja, A Bartelt, C John, L Cherradi, C Schlein, A Worthmann, ... Atherosclerosis 235 (2), e33-e34, 2014 | | 2014 |
Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution C Schlein, AW Fischer, F Sass, A Worthmann, K Tödter, MY Jaeckstein, ... Cell Reports 34 (2), 108624, 0 | | |