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Alex Avdeef
Alex Avdeef
Consultant, in-ADME Research
Verified email at in-adme.com - Homepage
Title
Cited by
Cited by
Year
Absorption and drug development: solubility, permeability, and charge state
A Avdeef
John Wiley & Sons, 2012
10152012
Physicochemical profiling (solubility, permeability and charge state)
A Avdeef
Current topics in medicinal chemistry 1 (4), 277-351, 2001
6912001
Coexistence of passive and carrier-mediated processes in drug transport
K Sugano, M Kansy, P Artursson, A Avdeef, S Bendels, L Di, GF Ecker, ...
Nature reviews Drug discovery 9 (8), 597-614, 2010
5932010
pH-Metric logP 10. Determination of liposomal membrane-water partition coefficients of lonizable drugs
A Avdeef, KJ Box, JEA Comer, C Hibbert, KY Tam
Pharmaceutical research 15 (2), 209-215, 1998
5001998
Coordination chemistry of microbial iron transport compounds. 9. Stability constants for catechol models of enterobactin
A Avdeef, SR Sofen, TL Bregante, KN Raymond
Journal of the American Chemical Society 100 (17), 5362-5370, 1978
4271978
Coordination chemistry of microbial iron transport compounds. 19. Stability constants and electrochemical behavior of ferric enterobactin and model complexes
WR Harris, CJ Carrano, SR Cooper, SR Sofen, AE Avdeef, JV McArdle, ...
Journal of the American Chemical Society 101 (20), 6097-6104, 1979
3791979
pH-metric solubility. 2: correlation between the acid-base titration and the saturation shake-flask solubility-pH methods
A Avdeef, CM Berger, C Brownell
Pharmaceutical research 17 (1), 85-89, 2000
3242000
Absorption classification of oral drugs based on molecular surface properties
CAS Bergström, M Strafford, L Lazorova, A Avdeef, K Luthman, ...
Journal of medicinal chemistry 46 (4), 558-570, 2003
3192003
Solubility of sparingly-soluble ionizable drugs
A Avdeef
Advanced drug delivery reviews 59 (7), 568-590, 2007
2942007
PH-metric log P 11. pKa determination of water-insoluble drugs in organic solvent–water mixtures
A Avdeef, KJ Box, JEA Comer, M Gilges, M Hadley, C Hibbert, ...
Journal of pharmaceutical and biomedical analysis 20 (4), 631-641, 1999
2891999
pH-Metric log P. 3. Glass electrode calibration in methanol-water, applied to pKa determination of water-insoluble substances
A Avdeef, JEA Comer, SJ Thomson
Analytical Chemistry 65 (1), 42-49, 1993
2781993
pH-metric log P. II: Refinement of partition coefficients and ionization constants of multiprotic substances
A Avdeef
Journal of pharmaceutical sciences 82 (2), 183-190, 1993
2701993
Classification analysis of P-glycoprotein substrate specificity
R Didziapetris, P Japertas, A Avdeef, A Petrauskas
Journal of drug targeting 11 (7), 391-406, 2003
2632003
PAMPA—critical factors for better predictions of absorption
A Avdeef, S Bendels, L Di, B Faller, M Kansy, K Sugano, Y Yamauchi
Journal of pharmaceutical sciences 96 (11), 2893-2909, 2007
2412007
PAMPA—a drug absorption in vitro model: 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones
M Bermejo, A Avdeef, A Ruiz, R Nalda, JA Ruell, O Tsinman, I González, ...
European Journal of Pharmaceutical Sciences 21 (4), 429-441, 2004
2212004
PH‐metric log P. Part 1. Difference plots for determining ion‐pair octanol‐water partition coefficients of multiprotic substances
A Avdeef
Quantitative Structure‐Activity Relationships 11 (4), 510-517, 1992
2171992
The rise of PAMPA
A Avdeef
Expert opinion on drug metabolism & toxicology 1 (2), 325-342, 2005
2152005
Caco-2 permeability of weakly basic drugs predicted with the Double-Sink PAMPA pKaflux method
A Avdeef, P Artursson, S Neuhoff, L Lazorova, J Grĺsjö, S Tavelin
European journal of pharmaceutical sciences 24 (4), 333-349, 2005
2142005
In vitro trans-monolayer permeability calculations: often forgotten assumptions
KA Youdim, A Avdeef, NJ Abbott
Drug Discovery Today 8 (21), 997-1003, 2003
1962003
Potentiometric pKa determination of water-insoluble compounds: validation study in methanol/water mixtures
K Takács-Novák, KJ Box, A Avdeef
International Journal of Pharmaceutics 151 (2), 235-248, 1997
1901997
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