A multistate tuberculosis pharmacometric model: a framework for studying anti-tubercular drug effects in vitro O Clewe, L Aulin, Y Hu, ARM Coates, USH Simonsson Journal of Antimicrobial Chemotherapy 71 (4), 964-974, 2016 | 54 | 2016 |
Design principles of collateral sensitivity-based dosing strategies LBS Aulin, A Liakopoulos, PH van der Graaf, DE Rozen, JGC van Hasselt Nature communications 12 (1), 5691, 2021 | 37 | 2021 |
Biomarker‐guided individualization of antibiotic therapy LBS Aulin, DW de Lange, MAA Saleh, PH van der Graaf, S Völler, ... Clinical Pharmacology & Therapeutics 110 (2), 346-360, 2021 | 36 | 2021 |
Population pharmacokinetics of unbound and total teicoplanin in critically ill pediatric patients LBS Aulin, P De Paepe, E Dhont, A de Jaeger, J Vande Walle, ... Clinical Pharmacokinetics 60, 353-363, 2021 | 13 | 2021 |
Allele-specific collateral and fitness effects determine the dynamics of fluoroquinolone resistance evolution A Liakopoulos, LBS Aulin, M Buffoni, E Fragkiskou, JG Coen van Hasselt, ... Proceedings of the National Academy of Sciences 119 (18), e2121768119, 2022 | 12 | 2022 |
Evaluating the prevalence of Hepatitis E virus infection in a large cohort of European blood donors, 2015–2018 K Healy, U Freij, M Ellerstad, LBS Aulin, L Brückle, H Hillmering, MS Chen, ... Journal of Viral Hepatitis 29 (9), 835-839, 2022 | 9 | 2022 |
A system pharmacology Boolean network model for the TLR4-mediated inflammatory response in early sepsis F Liu, LBS Aulin, SSA Kossen, J Cathalina, M Bremmer, AC Foks, ... Journal of Pharmacokinetics and Pharmacodynamics 49 (6), 645-655, 2022 | 6 | 2022 |
Modelling inflammatory biomarker dynamics in a human lipopolysaccharide (LPS) challenge study using delay differential equations F Liu, LBS Aulin, T Guo, EHJ Krekels, M Moerland, PH van der Graaf, ... British Journal of Clinical Pharmacology 88 (12), 5420-5427, 2022 | 6 | 2022 |
Distinct evolution of colistin resistance associated with experimental resistance evolution models in Klebsiella pneumoniae LBS Aulin, CIM Koumans, Y Haakman, W van Os, MEM Kraakman, ... Journal of Antimicrobial Chemotherapy 76 (2), 533-535, 2021 | 6 | 2021 |
Validation of a model predicting anti-infective lung penetration in the epithelial lining fluid of humans LBS Aulin, PA Valitalo, ML Rizk, SAG Visser, G Rao, PH van der Graaf, ... Pharmaceutical Research 35, 1-4, 2018 | 6 | 2018 |
Physiologically based modelling framework for prediction of pulmonary pharmacokinetics of antimicrobial target site concentrations LBS Aulin, ST Tandar, T van Zijp, E van Ballegooie, PH van der Graaf, ... Clinical Pharmacokinetics 61 (12), 1735-1748, 2022 | 4 | 2022 |
Barriers to global pharmacometrics: educational challenges and opportunities across the globe R Michelet, LBS Aulin, JM Borghardt, T Dalla Costa, P Denti, M Ibarra, ... CPT: Pharmacometrics & Systems Pharmacology 12 (6), 743, 2023 | 3 | 2023 |
Prevalence of parvovirus B19 viremia among german blood donations and the relationship to ABO and rhesus blood group antigens K Healy, LBS Aulin, U Freij, M Ellerstad, L Brückle, H Hillmering, TE Svae, ... The Journal of Infectious Diseases 227 (10), 1214-1218, 2023 | 2 | 2023 |
Ulcerative colitis and acute severe ulcerative colitis patients are overlooked in infliximab population pharmacokinetic models: results from a comprehensive review A Démaris, ESK Widigson, JFKF Ilvemark, C Steenholdt, JB Seidelin, ... Pharmaceutics 14 (10), 2095, 2022 | 2 | 2022 |
Characterizing the kinetics of presepsin and associated inflammatory biomarkers in human endotoxemia LBS Aulin, A Kleijburg, M Moerland, JGC van Hasselt Inflammation Research 71 (9), 999-1001, 2022 | 2 | 2022 |
Unraveling the effects of acute inflammation on pharmacokinetics: a model-based analysis focusing on renal glomerular filtration rate and cytochrome P450 3A4-mediated metabolism F Liu, LBS Aulin, ML Manson, EHJ Krekels, JGC van Hasselt European Journal of Drug Metabolism and Pharmacokinetics 48 (6), 623-631, 2023 | 1 | 2023 |
Bayesian framework for multi-source data integration-Application to human extrapolation from preclinical studies S Boulet, M Ursino, R Michelet, LBS Aulin, C Kloft, E Comets, S Zohar Statistical Methods in Medical Research 33 (4), 574-588, 2024 | | 2024 |
Inhalation of an immunomodulatory adjuvant to treat drug-resistant bacterial pneumonia J Pardessus, L Guillot, A Mayor, M Baldry, R Michelet, D Cayet, ... Revue des Maladies Respiratoires 41 (3), 214, 2024 | | 2024 |
INHALATION OF AN IMMUNOMODULATORY ADJUVANT TO TREAT DRUG-RESISTANT BACTERIAL PNEUMONIA J Pardessus, L Guillot, A Mayor, M Cabrera, D Le Pennec, R MacLoughlin, ... JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY 36 (6), A30-A30, 2023 | | 2023 |
Semi-mechanistic modeling of resistance development to β-lactam and β-lactamase-inhibitor combinations ST Tandar, LBS Aulin, EMJ Leemkuil, A Liakopoulos, JGC van Hasselt Journal of Pharmacokinetics and Pharmacodynamics, 1-13, 2023 | | 2023 |