| Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage W Lee, HA Leddy, Y Chen, SH Lee, NA Zelenski, AL McNulty, J Wu, ... Proceedings of the National Academy of Sciences 111 (47), E5114-E5122, 2014 | 401 | 2014 |
| UVA generates pyrimidine dimers in DNA directly Y Jiang, M Rabbi, M Kim, C Ke, W Lee, RL Clark, PA Mieczkowski, ... Biophysical journal 96 (3), 1151-1158, 2009 | 204 | 2009 |
| Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis W Lee, RJ Nims, A Savadipour, Q Zhang, HA Leddy, F Liu, AL McNulty, ... Proceedings of the National Academy of Sciences 118 (13), e2001611118, 2021 | 124 | 2021 |
| TRPV4 is necessary for trigeminal irritant pain and functions as a cellular formalin receptor Y Chen, P Kanju, Q Fang, SH Lee, PK Parekh, W Lee, C Moore, ... Pain 155 (12), 2662-2672, 2014 | 82 | 2014 |
| Role of piezo channels in joint health and injury W Lee, F Guilak, W Liedtke Current topics in membranes 79, 263-273, 2017 | 74 | 2017 |
| Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain P Kanju, Y Chen, W Lee, M Yeo, SH Lee, J Romac, R Shahid, P Fan, ... Scientific reports 6 (1), 26894, 2016 | 72 | 2016 |
| Fast and forceful refolding of stretched α-helical solenoid proteins M Kim, K Abdi, G Lee, M Rabbi, W Lee, M Yang, CJ Schofield, V Bennett, ... Biophysical journal 98 (12), 3086-3092, 2010 | 63 | 2010 |
| Mechanical unfolding of an ankyrin repeat protein D Serquera, W Lee, G Settanni, PE Marszalek, E Paci, LS Itzhaki Biophysical journal 98 (7), 1294-1301, 2010 | 56 | 2010 |
| Full reconstruction of a vectorial protein folding pathway by atomic force microscopy and molecular dynamics simulations W Lee, X Zeng, HX Zhou, V Bennett, W Yang, PE Marszalek Journal of Biological Chemistry 285 (49), 38167-38172, 2010 | 48 | 2010 |
| The role of mechanically-activated ion channels Piezo1, Piezo2, and TRPV4 in chondrocyte mechanotransduction and mechano-therapeutics for osteoarthritis W Gao, H Hasan, DE Anderson, W Lee Frontiers in cell and developmental biology 10, 885224, 2022 | 29 | 2022 |
| Mechanical anisotropy of ankyrin repeats W Lee, X Zeng, K Rotolo, M Yang, CJ Schofield, V Bennett, W Yang, ... Biophysical journal 102 (5), 1118-1126, 2012 | 26 | 2012 |
| Molecular Manipulation with Atomic Force Microscopy AS Duwez, N Willet CRC Press, 2011 | 26 | 2011 |
| Minimizing pulling geometry errors in atomic force microscope single molecule force spectroscopy M Rivera, W Lee, C Ke, PE Marszalek, DG Cole, RL Clark Biophysical journal 95 (8), 3991-3998, 2008 | 17 | 2008 |
| Mutation of conserved histidines alters tertiary structure and nanomechanics of consensus ankyrin repeats W Lee, J Strümpfer, V Bennett, K Schulten, PE Marszalek Journal of Biological Chemistry 287 (23), 19115-19121, 2012 | 13 | 2012 |
| Hydrogel swelling-mediated strain induces cell alignment at dentin interfaces D Fraser, T Nguyen, A Kotelsky, W Lee, M Buckley, DSW Benoit ACS Biomaterials Science & Engineering 8 (8), 3568-3575, 2022 | 10 | 2022 |
| Mechanics of polysaccharides W Lee, X Zeng, W Yang, PE Marszalek Molecular manipulation with atomic force microscopy, 2012 | 6 | 2012 |
| Effect of knee joint loading on chondrocyte mechano-vulnerability and severity of post-traumatic osteoarthritis induced by ACL-injury in mice A Kotelsky, A Elahi, CN Yigit, A Proctor, S Mannava, C Pröschel, W Lee Osteoarthritis and Cartilage Open 4 (1), 100227, 2022 | 2 | 2022 |
| Osteoarthritis: articular chondrocyte inflammatory signaling leads to enhanced gene expression and function of mechanotransduction channel Piezo1 as a pathogenic feed-forward … W Lee, RJ Nims, A Savadipour, H Leddy, F Liu, A McNulty, Y Chen, ... bioRxiv, 2020.05. 23.112565, 2020 | 2 | 2020 |
| Nanomechanics of Ankyrin Repeat Proteins W Lee Ph. D. thesis, Duke University, 2011 | 1 | 2011 |
| Nanomechanics of Ankyrin-R Repeats Probed by AFM and SMD Simulations W Lee, M Yang, CJ Schofield, PE Marszalek Biophysical Journal 98 (3), 447a, 2010 | 1 | 2010 |
Farshid GuilakOrthopaedic Surgery, Washington University; Shriners Hospitals for ChildrenBestätigte E-Mail-Adresse bei wustl.edu
