Peptide-level robust ridge regression improves estimation, sensitivity, and specificity in data-dependent quantitative label-free shotgun proteomics LJE Goeminne, K Gevaert, L Clement Molecular & Cellular Proteomics 15 (2), 657-668, 2016 | 94 | 2016 |
Experimental design and data-analysis in label-free quantitative LC/MS proteomics: A tutorial with MSqRob LJE Goeminne, K Gevaert, L Clement Journal of proteomics 171, 23-36, 2018 | 88 | 2018 |
Growth differentiation factor 15 protects against the aging‐mediated systemic inflammatory response in humans and mice JS Moon, LJE Goeminne, JT Kim, JW Tian, SH Kim, HT Nga, SG Kang, ... Aging cell 19 (8), e13195, 2020 | 73 | 2020 |
moFF: a robust and automated approach to extract peptide ion intensities A Argentini, LJE Goeminne, K Verheggen, N Hulstaert, A Staes, ... Nature methods 13 (12), 964-966, 2016 | 61 | 2016 |
Summarization vs peptide-based models in label-free quantitative proteomics: performance, pitfalls, and data analysis guidelines LJE Goeminne, A Argentini, L Martens, L Clement Journal of proteome research 14 (6), 2457-2465, 2015 | 54 | 2015 |
The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress TY Li, MB Sleiman, H Li, AW Gao, A Mottis, AM Bachmann, GE Alam, X Li, ... Nature aging 1 (2), 165-178, 2021 | 51 | 2021 |
Robust summarization and inference in proteome-wide label-free quantification A Sticker, L Goeminne, L Martens, L Clement Molecular & Cellular Proteomics 19 (7), 1209-1219, 2020 | 50 | 2020 |
MSqRob takes the missing hurdle: uniting intensity-and count-based proteomics LJE Goeminne, A Sticker, L Martens, K Gevaert, L Clement Analytical chemistry 92 (9), 6278-6287, 2020 | 49 | 2020 |
The mouse metallomic landscape of aging and metabolism JD Morel, L Sauzéat, LJE Goeminne, P Jha, E Williams, RH Houtkooper, ... Nature communications 13 (1), 607, 2022 | 21 | 2022 |
Inhibition of sphingolipid de novo synthesis counteracts muscular dystrophy PP Laurila, P Luan, M Wohlwend, N Zanou, B Crisol, T Imamura de Lima, ... Science Advances 8 (4), eabh4423, 2022 | 21 | 2022 |
Identification of immune-responsive gene 1 (IRG1) as a target of A20 E Van Quickelberghe, A Martens, LJE Goeminne, L Clement, G van Loo, ... Journal of proteome research 17 (6), 2182-2191, 2018 | 17 | 2018 |
COX7A2L genetic variants determine cardiorespiratory fitness in mice and human G Benegiamo, M Bou Sleiman, M Wohlwend, S Rodríguez-López, ... Nature metabolism 4 (10), 1336-1351, 2022 | 14 | 2022 |
The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression G Benegiamo, GVG von Alvensleben, S Rodríguez-López, LJE Goeminne, ... Journal of Experimental Medicine 220 (4), e20221738, 2023 | 12 | 2023 |
Integrative systems analysis identifies genetic and dietary modulators of bile acid homeostasis H Li, A Perino, Q Huang, GVG Von Alvensleben, A Banaei-Esfahani, ... Cell Metabolism 34 (10), 1594-1610. e4, 2022 | 11 | 2022 |
Genetic background and sex control the outcome of high-fat diet feeding in mice AM Bachmann, JD Morel, G El Alam, S Rodríguez-López, LJE Goeminne, ... IScience 25 (6), 2022 | 10 | 2022 |
Inhibiting de novo ceramide synthesis restores mitochondrial and protein homeostasis in muscle aging TI Lima, PP Laurila, M Wohlwend, JD Morel, LJE Goeminne, H Li, ... Science Translational Medicine 15 (696), eade6509, 2023 | 9 | 2023 |
Evidence for a neuromuscular circuit involving hypothalamic interleukin-6 in the control of skeletal muscle metabolism CK Katashima, T de Oliveira Micheletti, RR Braga, RS Gaspar, ... Science advances 8 (30), eabm7355, 2022 | 8 | 2022 |
Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation W Mitchell, LJE Goeminne, A Tyshkovskiy, S Zhang, JY Chen, JA Paulo, ... Elife 12, RP90579, 2024 | 3 | 2024 |
Statistical methods for differential proteomics at peptide and protein level L Goeminne Ghent University, 2019 | 2 | 2019 |
Gene network based analysis identifies a coexpression module involved in regulating plasma lipids with high-fat diet response F Xu, JD Ziebarth, LJE Goeminne, J Gao, EG Williams, LD Quarles, ... The Journal of nutritional biochemistry 119, 109398, 2023 | 1 | 2023 |