Stereochemistry of mephedrone neuropharmacology: enantiomer‐specific behavioural and neurochemical effects in rats RA Gregg, MH Baumann, JS Partilla, JS Bonano, A Vouga, CS Tallarida, ... British journal of pharmacology 172 (3), 883-894, 2015 | 89 | 2015 |
Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth TE Messick, GR Smith, SS Soldan, ME McDonnell, JS Deakyne, ... Science translational medicine 11 (482), eaau5612, 2019 | 85 | 2019 |
Synthesis of polysubstituted pyrroles from sulfinimines (N-sulfinyl imines) FA Davis, KA Bowen, H Xu, V Velvadapu Tetrahedron 64 (19), 4174-4182, 2008 | 62 | 2008 |
Desmethyl macrolides: synthesis and evaluation of 4, 10-didesmethyl telithromycin V Velvadapu, I Glassford, M Lee, T Paul, C DeBrosse, D Klepacki, ... ACS medicinal chemistry letters 3 (3), 211-215, 2012 | 35 | 2012 |
Total synthesis of (−)-4, 8, 10-tridesmethyl telithromycin V Velvadapu, T Paul, B Wagh, I Glassford, C DeBrosse, RB Andrade The Journal of organic chemistry 76 (18), 7516-7527, 2011 | 34 | 2011 |
Desmethyl macrolides: synthesis and evaluation of 4, 8, 10-tridesmethyl telithromycin V Velvadapu, T Paul, B Wagh, D Klepacki, O Guvench, A MacKerell Jr, ... ACS Medicinal Chemistry Letters 2 (1), 68-72, 2011 | 28 | 2011 |
Concise syntheses of d-desosamine, 2-thiopyrimidinyl desosamine donors, and methyl desosaminide analogues from d-glucose V Velvadapu, RB Andrade Carbohydrate research 343 (1), 145-150, 2008 | 28 | 2008 |
Characterization of a series of 4-aminoquinolines that stimulate caspase-7 mediated cleavage of TDP-43 and inhibit its function JA Cassel, ME McDonnell, V Velvadapu, V Andrianov, AB Reitz Biochimie 94 (9), 1974-1981, 2012 | 27 | 2012 |
Fragment-based drug discovery V Velvadapu, BT Farmer, AB Reitz Practice of Medicinal Chemistry 4, Pages161-180, 2015 | 24 | 2015 |
Implementation of the CYP Index for the Design of Selective Tryptophan-2, 3-dioxygenase Inhibitors BT Parr, R Pastor, BD Sellers, Z Pei, FA Jaipuri, GM Castanedo, ... ACS Medicinal Chemistry Letters 11 (4), 541-549, 2020 | 22 | 2020 |
Desmethyl macrolides: synthesis and evaluation of 4-desmethyl telithromycin I Glassford, M Lee, B Wagh, V Velvadapu, T Paul, G Sandelin, ... ACS Medicinal Chemistry Letters 5 (9), 1021-1026, 2014 | 21 | 2014 |
Oxidation and reduction potentials of 8-vinyladenosine measured by cyclic voltammetry: Implications for photoinduced electron transfer quenching of a fluorescent adenine analog M Narayanan, G Kodali, VR Singh, V Velvadapu, RJ Stanley Journal of Photochemistry and Photobiology A: Chemistry 249, 9-14, 2012 | 13 | 2012 |
Prodrugs of riluzole and their method of use GR Smith, AB Reitz, M McDonnell, S Chen, MD Vera, BE Blass, ... US Patent 9,725,427, 2017 | 12 | 2017 |
The Practice of Medicinal Chemistry V Velvadapu, BT Farmer, AB Reitz ScienceDirect: Amsterdam, Netherlands, 2015 | 7 | 2015 |
Desmethyl macrolide analogues to address antibiotic resistance: total synthesis and biological evaluation of 4, 8, 10-Tridesmethyl telithromycin V Velvadapu, T Paul, B Wagh, D Klepacki, O Guvench, A MacKerell Jr, ... ACS medicinal chemistry letters 2 (1), 68, 2011 | 7 | 2011 |
TDO2 Inhibitors X Lin, PW Yuen, R Mendonca, B Parr, R Pastor, Z Pei, L Gazzard, ... US Patent 10,800,780, 2020 | 4 | 2020 |
Prodrugs of riluzole and their method of use GR Smith, AB Reitz, M McDonnell, S Chen, MD Vera, BE Blass, ... US Patent 10,562,870, 2020 | 4 | 2020 |
Intramolecular rearrangement of α-amino acid amide derivatives of 2-aminobenzothiazoles JC Pelletier, V Velvadapu, ME McDonnell, JE Wrobel, AB Reitz Tetrahedron letters 55 (30), 4193-4195, 2014 | 3 | 2014 |
Photodesulfinylation of optically active N-sulfinyl amines FA Davis, T Ramachandar, Y Zhang, J Chai, H Qiu, J Deng, V Velvadapu Tetrahedron Letters 51 (31), 4042-4044, 2010 | 3 | 2010 |
Detecting and correcting for changes to an analyte indicator A DeHennis, M Mortellaro, A Chavan, V Velvadapu, P Huffstetler, THJ Kim, ... US Patent 10,827,962, 2020 | 2 | 2020 |