An inhibitor of oxidative phosphorylation exploits cancer vulnerability JR Molina, Y Sun, M Protopopova, S Gera, M Bandi, C Bristow, T McAfoos, ... Nature medicine 24 (7), 1036-1046, 2018 | 715 | 2018 |
Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML Z Zeng, Y Xi Shi, IJ Samudio, RY Wang, X Ling, O Frolova, M Levis, ... Blood, The Journal of the American Society of Hematology 113 (24), 6215-6224, 2009 | 618 | 2009 |
Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptotic proteins M Konopleva, S Konoplev, W Hu, AY Zaritskey, BV Afanasiev, M Andreeff Leukemia 16 (9), 1713-1724, 2002 | 505 | 2002 |
Ph-like acute lymphoblastic leukemia: a high-risk subtype in adults N Jain, KG Roberts, E Jabbour, K Patel, AK Eterovic, K Chen, ... Blood, The Journal of the American Society of Hematology 129 (5), 572-581, 2017 | 370 | 2017 |
Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition JA Burger, DA Landau, A Taylor-Weiner, I Bozic, H Zhang, K Sarosiek, ... Nature communications 7 (1), 11589, 2016 | 370 | 2016 |
Reciprocal leukemia-stroma VCAM-1/VLA-4-dependent activation of NF-κB mediates chemoresistance R Jacamo, Y Chen, Z Wang, W Ma, M Zhang, EL Spaeth, Y Wang, ... Blood, The Journal of the American Society of Hematology 123 (17), 2691-2702, 2014 | 314 | 2014 |
CXCR4 up-regulation by imatinib induces chronic myelogenous leukemia (CML) cell migration to bone marrow stroma and promotes survival of quiescent CML cells L Jin, Y Tabe, S Konoplev, Y Xu, CE Leysath, H Lu, S Kimura, A Ohsaka, ... Molecular cancer therapeutics 7 (1), 48-58, 2008 | 253 | 2008 |
10-day decitabine with venetoclax for newly diagnosed intensive chemotherapy ineligible, and relapsed or refractory acute myeloid leukaemia: a single-centre, phase 2 trial CD DiNardo, A Maiti, CR Rausch, N Pemmaraju, K Naqvi, NG Daver, ... The Lancet Haematology 7 (10), e724-e736, 2020 | 245 | 2020 |
A phase I first-in-human trial of bardoxolone methyl in patients with advanced solid tumors and lymphomas DS Hong, R Kurzrock, JG Supko, X He, A Naing, J Wheler, D Lawrence, ... Clinical cancer research 18 (12), 3396-3406, 2012 | 244 | 2012 |
Extranodal NK/T-cell lymphoma, nasal type: a report of 73 cases at MD Anderson Cancer Center S Li, X Feng, T Li, S Zhang, Z Zuo, P Lin, S Konoplev, CE Bueso-Ramos, ... The American journal of surgical pathology 37 (1), 14-23, 2013 | 242 | 2013 |
Overexpression of CXCR4 predicts adverse overall and event‐free survival in patients with unmutated FLT3 acute myeloid leukemia with normal karyotype S Konoplev, GZ Rassidakis, E Estey, H Kantarjian, CI Liakou, X Huang, ... Cancer: Interdisciplinary International Journal of the American Cancer …, 2007 | 181 | 2007 |
Immunophenotypic profile of lymphoplasmacytic lymphoma/Waldenström macroglobulinemia S Konoplev, LJ Medeiros, CE Bueso-Ramos, JL Jorgensen, P Lin American journal of clinical pathology 124 (3), 414-420, 2005 | 179 | 2005 |
Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes P Matre, J Velez, R Jacamo, Y Qi, X Su, T Cai, SM Chan, A Lodi, ... Oncotarget 7 (48), 79722, 2016 | 168 | 2016 |
Concomitant inhibition of DNA methyltransferase and BCL-2 protein function synergistically induce mitochondrial apoptosis in acute myelogenous leukemia cells T Tsao, Y Shi, S Kornblau, H Lu, S Konoplev, A Antony, V Ruvolo, YH Qiu, ... Annals of hematology 91, 1861-1870, 2012 | 160 | 2012 |
IDH mutations in acute myeloid leukemia D Rakheja, S Konoplev, LJ Medeiros, W Chen Human pathology 43 (10), 1541-1551, 2012 | 158 | 2012 |
Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment O Frolova, I Samudio, JM Benito, R Jacamo, SM Kornblau, A Markovic, ... Cancer biology & therapy 13 (10), 858-870, 2012 | 144 | 2012 |
Molecular characterization of de novo Philadelphia chromosome-positive acute myeloid leukemia S Konoplev, CC Yin, SM Kornblau, HM Kantarjian, M Konopleva, ... Leukemia & lymphoma 54 (1), 138-144, 2013 | 143 | 2013 |
Cytomegalovirus pneumonia in adult autologous blood and marrow transplant recipients S Konoplev, RE Champlin, S Giralt, NT Ueno, I Khouri, I Raad, K Rolston, ... Bone marrow transplantation 27 (8), 877-881, 2001 | 141 | 2001 |
Pronounced hypoxia in models of murine and human leukemia: high efficacy of hypoxia-activated prodrug PR-104 J Benito, Y Shi, B Szymanska, H Carol, I Boehm, H Lu, S Konoplev, ... PloS one 6 (8), e23108, 2011 | 139 | 2011 |
Minimal residual disease assessed by multi‐parameter flow cytometry is highly prognostic in adult patients with acute lymphoblastic leukaemia F Ravandi, JL Jorgensen, SM O'Brien, E Jabbour, DA Thomas, ... British journal of haematology 172 (3), 392-400, 2016 | 131 | 2016 |