Jussi Taipale
Jussi Taipale
University of Cambridge, Department of Biochemistry
Bestätigte E-Mail-Adresse bei - Startseite
Zitiert von
Zitiert von
The human transcription factors
SA Lambert, A Jolma, LF Campitelli, PK Das, Y Yin, M Albu, X Chen, ...
Cell 172 (4), 650-665, 2018
The Hedgehog and Wnt signalling pathways in cancer
J Taipale, PA Beachy
nature 411 (6835), 349-354, 2001
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
JK Chen, J Taipale, MK Cooper, PA Beachy
Genes & development 16 (21), 2743-2748, 2002
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
MJ Karkkainen, P Haiko, K Sainio, J Partanen, J Taipale, TV Petrova, ...
Nature immunology 5 (1), 74-80, 2004
Effects of oncogenic mutations in Smoothenedand Patched can be reversed by cyclopamine
J Taipale, JK Chen, MK Cooper, B Wang, RK Mann, L Milenkovic, ...
Nature 406, 1005-1009, 2000
Hedgehog: functions and mechanisms
M Varjosalo, J Taipale
Genes & development 22 (18), 2454-2472, 2008
DNA-Binding Specificities of Human Transcription Factors
A Jolma, J Yan, T Whitington, J Toivonen, KR Nitta, P Rastas, ...
Cell 152 (1), 327-339, 2013
Counting absolute numbers of molecules using unique molecular identifiers
T Kivioja, A Vähärautio, K Karlsson, M Bonke, M Enge, S Linnarsson, ...
Nature methods 9 (1), 72-74, 2012
Growth factors in the extracellular matrix
J Taipale, J Keski‐Oja
The FASEB Journal 11 (1), 51-59, 1997
Cardiovascular failure in mouse embryos deficient in VEGF receptor-3
DJ Dumont, L Jussila, J Taipale, A Lymboussaki, T Mustonen, K Pajusola, ...
Science 282 (5390), 946-949, 1998
Small molecule modulation of Smoothened activity
JK Chen, J Taipale, KE Young, T Maiti, PA Beachy
Proceedings of the National Academy of Sciences 99 (22), 14071-14076, 2002
CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response
E Haapaniemi, S Botla, J Persson, B Schmierer, J Taipale
Nature medicine 24 (7), 927-930, 2018
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Y Yin, E Morgunova, A Jolma, E Kaasinen, B Sahu, S Khund-Sayeed, ...
Science 356 (6337), eaaj2239, 2017
Medulloblastoma growth inhibition by hedgehog pathway blockade
DM Berman, SS Karhadkar, AR Hallahan, JI Pritchard, CG Eberhart, ...
Science 297 (5586), 1559, 2002
Patched acts catalytically to suppress the activity of Smoothened
J Taipale, MK Cooper, T Maiti, PA Beachy
Nature 418 (6900), 892-896, 2002
VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer
R Valtola, P Salven, P Heikkilä, J Taipale, H Joensuu, M Rehn, ...
The American journal of pathology 154 (5), 1381-1390, 1999
MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas
N Mäkinen, M Mehine, J Tolvanen, E Kaasinen, Y Li, HJ Lehtonen, ...
Science 334 (6053), 252-255, 2011
Genome‐wide analysis of ETS‐family DNA‐binding in vitro and in vivo
GH Wei, G Badis, MF Berger, T Kivioja, K Palin, M Enge, M Bonke, ...
The EMBO journal 29 (13), 2147-2160, 2010
Latent transforming growth factor-beta 1 associates to fibroblast extracellular matrix via latent TGF-beta binding protein
J Taipale, K Miyazono, CH Heldin, J Keski-Oja
The Journal of cell biology 124 (1), 171-181, 1994
Genome-wide prediction of mammalian enhancers based on analysis of transcription-factor binding affinity
O Hallikas, K Palin, N Sinjushina, R Rautiainen, J Partanen, E Ukkonen, ...
Cell 124 (1), 47-59, 2006
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