Jussi Taipale

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Arttu JolmaPost-doctoral fellowVerified email at utoronto.ca
Philip BeachyProfessor of Urology, Developmental Biology, Stanford UniversityVerified email at stanford.edu
Markku VarjosaloUniversity of HelsinkiVerified email at helsinki.fi
Jian YanDepartment of Biomedical Sciences, City University of Hong KongVerified email at cityu.edu.hk
Kimmo PalinCancer Researcher, Research Program in Cancer Research, Univeristy of HelsinkiVerified email at helsinki.fi
Martin EngeKarolinska InstitutetVerified email at ki.se
Yimeng YinTongji UniversityVerified email at tongji.edu.cn
MorgunovaKarolinska InstituteVerified email at ki.se
Mikko TurunenAssociate Research Scientist, Columbia UniversityVerified email at cumc.columbia.edu
Riku KatainenUniversity of HelsinkiVerified email at helsinki.fi
Biswajyoti SahuGroup leader, NCMM, University of Oslo | Principal Investigator, University of HelsinkiVerified email at helsinki.fi
Timothy R. HughesUniversity of TorontoVerified email at utoronto.ca
Kazuhiro R. NittaJuntendo UnivVerified email at ki.se
Anna VähärautioPI, University of HelsinkiVerified email at helsinki.fi
James K ChenProfessor of Chemical and Systems Biology, Developmental Biology, and Chemistry; Stanford UniversityVerified email at stanford.edu
Mikael BjörklundZhejiang University-University of Edinburgh Institute, Zhejiang UniversityVerified email at intl.zju.edu.cn
Bernhard SchmiererKarolinska InstitutetVerified email at ki.se
Alexandra GylfeResearch and Development Lead, Human Longevity, Inc.Verified email at humanlongevity.com
Inderpreet SurKarolinska InstituteVerified email at ki.se
Jarkko ToivonenProject researcher, Finnish Red Cross Blood ServiceVerified email at veripalvelu.fi

Jussi Taipale

University of Cambridge, Department of Biochemistry

Verified email at cam.ac.uk - Homepage

Growth Control Transcription Functional Genomics Solving Biology


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The human transcription factors SA Lambert, A Jolma, LF Campitelli, PK Das, Y Yin, M Albu, X Chen, ... Cell 172 (4), 650-665, 2018	2395	2018
The Hedgehog and Wnt signalling pathways in cancer J Taipale, PA Beachy nature 411 (6835), 349-354, 2001	1900	2001
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened JK Chen, J Taipale, MK Cooper, PA Beachy Genes & development 16 (21), 2743-2748, 2002	1746	2002
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins MJ Karkkainen, P Haiko, K Sainio, J Partanen, J Taipale, TV Petrova, ... Nature immunology 5 (1), 74-80, 2004	1733	2004
Effects of oncogenic mutations in Smoothenedand Patched can be reversed by cyclopamine J Taipale, JK Chen, MK Cooper, B Wang, RK Mann, L Milenkovic, ... Nature 406, 1005-1009, 2000	1555	2000
Hedgehog: functions and mechanisms M Varjosalo, J Taipale Genes & development 22 (18), 2454-2472, 2008	1438	2008
DNA-Binding Specificities of Human Transcription Factors A Jolma, J Yan, T Whitington, J Toivonen, KR Nitta, P Rastas, ... Cell 152 (1), 327-339, 2013	1289	2013
Growth factors in the extracellular matrix J Taipale, J Keski‐Oja The FASEB Journal 11 (1), 51-59, 1997	1197	1997
Counting absolute numbers of molecules using unique molecular identifiers T Kivioja, A Vähärautio, K Karlsson, M Bonke, M Enge, S Linnarsson, ... Nature methods 9 (1), 72-74, 2012	1188	2012
Cardiovascular failure in mouse embryos deficient in VEGF receptor-3 DJ Dumont, L Jussila, J Taipale, A Lymboussaki, T Mustonen, K Pajusola, ... Science 282 (5390), 946-949, 1998	1166	1998
Small molecule modulation of Smoothened activity JK Chen, J Taipale, KE Young, T Maiti, PA Beachy Proceedings of the National Academy of Sciences 99 (22), 14071-14076, 2002	1125	2002
CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response E Haapaniemi, S Botla, J Persson, B Schmierer, J Taipale Nature medicine 24 (7), 927-930, 2018	1032	2018
Medulloblastoma growth inhibition by hedgehog pathway blockade DM Berman, SS Karhadkar, AR Hallahan, JI Pritchard, CG Eberhart, ... Science 297 (5586), 1559, 2002	1025	2002
Impact of cytosine methylation on DNA binding specificities of human transcription factors Y Yin, E Morgunova, A Jolma, E Kaasinen, B Sahu, S Khund-Sayeed, ... Science 356 (6337), eaaj2239, 2017	1019	2017
Patched acts catalytically to suppress the activity of Smoothened J Taipale, MK Cooper, T Maiti, PA Beachy Nature 418 (6900), 892-896, 2002	1007	2002
VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer R Valtola, P Salven, P Heikkilä, J Taipale, H Joensuu, M Rehn, ... The American journal of pathology 154 (5), 1381-1390, 1999	770	1999
MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas N Mäkinen, M Mehine, J Tolvanen, E Kaasinen, Y Li, HJ Lehtonen, ... Science 334 (6053), 252-255, 2011	700	2011
Genome‐wide analysis of ETS‐family DNA‐binding in vitro and in vivo GH Wei, G Badis, MF Berger, T Kivioja, K Palin, M Enge, M Bonke, ... The EMBO journal 29 (13), 2147-2160, 2010	646	2010
Latent transforming growth factor-beta 1 associates to fibroblast extracellular matrix via latent TGF-beta binding protein J Taipale, K Miyazono, CH Heldin, J Keski-Oja The Journal of cell biology 124 (1), 171-181, 1994	613	1994
Minimizing the risk of reporting false positives in large-scale RNAi screens CJ Echeverri, PA Beachy, B Baum, M Boutros, F Buchholz, SK Chanda, ... Nature methods 3 (10), 777-779, 2006	589	2006

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