Jussi Taipale
Jussi Taipale
University of Cambridge, Department of Biochemistry
Verified email at cam.ac.uk
TitleCited byYear
The Hedgehog and Wnt signalling pathways in cancer
J Taipale, PA Beachy
nature 411 (6835), 349, 2001
15952001
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
JK Chen, J Taipale, MK Cooper, PA Beachy
Genes & development 16 (21), 2743-2748, 2002
14242002
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
MJ Karkkainen, P Haiko, K Sainio, J Partanen, J Taipale, TV Petrova, ...
Nature immunology 5 (1), 74, 2004
13202004
Effects of oncogenic mutations in Smoothenedand Patched can be reversed by cyclopamine
J Taipale, JK Chen, MK Cooper, B Wang, RK Mann, L Milenkovic, ...
Nature 406, 1005-1009, 2000
13152000
Hedgehog: functions and mechanisms
M Varjosalo, J Taipale
Genes & development 22 (18), 2454-2472, 2008
10192008
Cardiovascular failure in mouse embryos deficient in VEGF receptor-3
DJ Dumont, L Jussila, J Taipale, A Lymboussaki, T Mustonen, K Pajusola, ...
Science 282 (5390), 946-949, 1998
9681998
Growth factors in the extracellular matrix.
J Taipale, J Keski-Oja
The FASEB Journal 11 (1), 51-59, 1997
9631997
Medulloblastoma growth inhibition by hedgehog pathway blockade
DM Berman, SS Karhadkar, AR Hallahan, JI Pritchard, CG Eberhart, ...
Science 297 (5586), 1559, 2002
9082002
Small molecule modulation of Smoothened activity
JK Chen, J Taipale, KE Young, T Maiti, PA Beachy
Proceedings of the National Academy of Sciences 99 (22), 14071-14076, 2002
8922002
Patched acts catalytically to suppress the activity of Smoothened
J Taipale, MK Cooper, T Maiti, PA Beachy
Nature 418 (6900), 892, 2002
7982002
DNA-Binding Specificities of Human Transcription Factors
A Jolma, J Yan, T Whitington, J Toivonen, KR Nitta, P Rastas, ...
Cell 152 (1), 327-339, 2013
7122013
VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer
R Valtola, P Salven, P Heikkilä, J Taipale, H Joensuu, M Rehn, ...
The American journal of pathology 154 (5), 1381-1390, 1999
6861999
Counting absolute numbers of molecules using unique molecular identifiers
T Kivioja, A Vähärautio, K Karlsson, M Bonke, M Enge, S Linnarsson, ...
Nature methods 9 (1), 72, 2012
5482012
Genome-wide prediction of mammalian enhancers based on analysis of transcription-factor binding affinity
O Hallikas, K Palin, N Sinjushina, R Rautiainen, J Partanen, E Ukkonen, ...
Cell 124 (1), 47-59, 2006
5032006
Latent transforming growth factor-beta 1 associates to fibroblast extracellular matrix via latent TGF-beta binding protein
J Taipale, K Miyazono, CH Heldin, J Keski-Oja
The Journal of cell biology 124 (1), 171-181, 1994
4921994
Genome‐wide analysis of ETS‐family DNA‐binding in vitro and in vivo
GH Wei, G Badis, MF Berger, T Kivioja, K Palin, M Enge, M Bonke, ...
The EMBO journal 29 (13), 2147-2160, 2010
4702010
The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling
S Tuupanen, M Turunen, R Lehtonen, O Hallikas, S Vanharanta, T Kivioja, ...
Nature genetics 41 (8), 885, 2009
4672009
Minimizing the risk of reporting false positives in large-scale RNAi screens
CJ Echeverri, PA Beachy, B Baum, M Boutros, F Buchholz, SK Chanda, ...
Nature methods 3 (10), 777, 2006
4492006
Human mast cell chymase and leukocyte elastase release latent transforming growth factor-β1 from the extracellular matrix of cultured human epithelial and endothelial cells
J Taipale, J Lohi, J Saarinen, PT Kovanen, J Keski-Oja
Journal of Biological Chemistry 270 (9), 4689-4696, 1995
4401995
MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas
N Mäkinen, M Mehine, J Tolvanen, E Kaasinen, Y Li, HJ Lehtonen, ...
Science 334 (6053), 252-255, 2011
4272011
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Articles 1–20