Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes P Matre, J Velez, R Jacamo, Y Qi, X Su, T Cai, SM Chan, A Lodi, ... Oncotarget 7 (48), 79722, 2016 | 168 | 2016 |
Choline uptake and metabolism modulate macrophage IL-1β and IL-18 production E Sanchez-Lopez, Z Zhong, A Stubelius, SR Sweeney, LM Booshehri, ... Cell metabolism 29 (6), 1350-1362. e7, 2019 | 165 | 2019 |
Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia Q Zhang, B Riley-Gillis, L Han, Y Jia, A Lodi, H Zhang, S Ganesan, R Pan, ... Signal transduction and targeted therapy 7 (1), 51, 2022 | 70 | 2022 |
Starving cancer from the outside and inside: separate and combined effects of calorie restriction and autophagy inhibition on Ras-driven tumors LM Lashinger, CH O’Flanagan, SM Dunlap, AJ Rasmussen, S Sweeney, ... Cancer & metabolism 4, 1-11, 2016 | 48 | 2016 |
Serum metabolomic profiling predicts synovial gene expression in rheumatoid arthritis R Narasimhan, R Coras, SB Rosenthal, SR Sweeney, A Lodi, S Tiziani, ... Arthritis research & therapy 20, 1-11, 2018 | 45 | 2018 |
Metabolomic profiling predicts outcome of rituximab therapy in rheumatoid arthritis SR Sweeney, A Kavanaugh, A Lodi, B Wang, D Boyle, S Tiziani, M Guma RMD open 2 (2), e000289, 2016 | 39 | 2016 |
Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia N Baran, A Lodi, Y Dhungana, S Herbrich, M Collins, S Sweeney, ... Nature communications 13 (1), 2801, 2022 | 29 | 2022 |
Gilteritinib Inhibits Glutamine Uptake and Utilization in FLT3-ITD–Positive AML ME Zavorka Thomas, X Lu, Z Talebi, JY Jeon, DR Buelow, AA Gibson, ... Molecular cancer therapeutics 20 (11), 2207-2217, 2021 | 29 | 2021 |
Deletion of the neural tube defect–associated gene Mthfd1l disrupts one-carbon and central energy metabolism in mouse embryos JD Bryant, SR Sweeney, E Sentandreu, M Shin, H Ipas, B Xhemalce, ... Journal of Biological Chemistry 293 (16), 5821-5833, 2018 | 29 | 2018 |
Novel strategy for untargeted chiral metabolomics using liquid chromatography-high resolution tandem mass spectrometry R Pandey, M Collins, X Lu, SR Sweeney, J Chiou, A Lodi, S Tiziani Analytical chemistry 93 (14), 5805-5814, 2021 | 22 | 2021 |
Identification of a synergistic combination of dimethylaminoparthenolide and shikonin alters metabolism and inhibits proliferation of pediatric precursor‐B cell acute … SR Sweeney, M Collins, R Pandey, J Chiou, A Lodi, S Tiziani Molecular Carcinogenesis 59 (4), 399-411, 2020 | 22 | 2020 |
A survey of orbitrap all ion fragmentation analysis assessed by an R MetaboList package to study small-molecule metabolites E Sentandreu, MD Peris-Díaz, SR Sweeney, J Chiou, N Muñoz, S Tiziani Chromatographia 81, 981-994, 2018 | 21 | 2018 |
R-metabolist 2: A flexible tool for metabolite annotation from high-resolution data-independent acquisition mass spectrometry analysis MD Peris-Díaz, SR Sweeney, O Rodak, E Sentandreu, S Tiziani Metabolites 9 (9), 187, 2019 | 9 | 2019 |
Chemometrics-assisted optimization of liquid chromatography-quadrupole-time-of-flight mass spectrometry analysis for targeted metabolomics MD Peris-Díaz, O Rodak, SR Sweeney, A Krężel, E Sentandreu Talanta 199, 380-387, 2019 | 9 | 2019 |
Mitochondrial Complex I inhibitor IACS-010759 reverses the NOTCH1-driven metabolic reprogramming in T-ALL via blockade of oxidative phosphorylation: Synergy with chemotherapy … N Baran, A Lodi, SR Sweeney, P Renu, VM Kuruvilla, A Cavazos, ... Blood 132, 4020, 2018 | 7 | 2018 |
Correction: Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia Q Zhang, B Riley-Gillis, L Han, Y Jia, A Lodi, H Zhang, S Ganesan, R Pan, ... Signal Transduction and Targeted Therapy 7, 2022 | 3 | 2022 |
Inhibition of Oxphos with Iacs-010759 Depletes AML Leukemia Initiating Cells (LIC) in Vitro and Improves Survival in Pre-Clinical AML Models N Baran, L Han, SR Sweeney, A Lodi, S Herbrich, A Cavazos, H Ma, ... Blood 130, 1350, 2017 | 2 | 2017 |
Novel Nanomolar Potency Mitochondrial Complex I Inhibitor Iacs-1131 Selectively Kills Oxphos-Dependent AML Cells P Matre, M Protopopova, N Feng, J Gay, J Greer, J Velez, H Mu, A Lodi, ... Blood 124 (21), 622, 2014 | 2 | 2014 |
Overcoming NOTCH1-driven chemoresistance in T-cell acute lymphoblastic leukemia via metabolic intervention with oxphos inhibitor N Baran, A Lodi, Y Dhungana, SR Sweeney, P Renu, S Herbrich, FW Hoff, ... Blood 136, 18-20, 2020 | 1 | 2020 |
Glutaminase Inhibition Overcomes Acquired Resistance to Mitochondrial Complex I in NOTCH1-Driven T-Cell Acute Lymphoblastic Leukemias (T-ALL) Via Block of Glutamine Driven … N Baran, A Lodi, SR Sweeney, VM Kuruvilla, A Cavazos, D Herranz, ... Blood 134, 806, 2019 | 1 | 2019 |