| Human haematopoietic stem cell lineage commitment is a continuous process L Velten, SF Haas, S Raffel, S Blaszkiewicz, S Islam, BP Hennig, C Hirche, ... Nature cell biology 19 (4), 271-281, 2017 | 936 | 2017 |
| Myelodysplastic cells in patients reprogram mesenchymal stromal cells to establish a transplantable stem cell niche disease unit H Medyouf, M Mossner, JC Jann, F Nolte, S Raffel, C Herrmann, A Lier, ... Cell stem cell 14 (6), 824-837, 2014 | 423 | 2014 |
| BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation S Raffel, M Falcone, N Kneisel, J Hansson, W Wang, C Lutz, L Bullinger, ... Nature 551 (7680), 384-388, 2017 | 320 | 2017 |
| Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion AM Paczulla, K Rothfelder, S Raffel, M Konantz, J Steinbacher, H Wang, ... Nature 572 (7768), 254-259, 2019 | 300 | 2019 |
| Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states S Triana, D Vonficht, L Jopp-Saile, S Raffel, R Lutz, D Leonce, M Antes, ... Nature immunology 22 (12), 1577-1589, 2021 | 101 | 2021 |
| Hypermutation of the inactive X chromosome is a frequent event in cancer N Jäger, M Schlesner, DTW Jones, S Raffel, JP Mallm, KM Junge, ... Cell 155 (3), 567-581, 2013 | 89 | 2013 |
| Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics L Velten, BA Story, P Hernández-Malmierca, S Raffel, DR Leonce, ... Nature communications 12 (1), 1366, 2021 | 87 | 2021 |
| The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition G Varano, S Raffel, M Sormani, F Zanardi, S Lonardi, C Zasada, ... Nature 546 (7657), 302-306, 2017 | 80 | 2017 |
| Proteomic cornerstones of hematopoietic stem cell differentiation: distinct signatures of multipotent progenitors and myeloid committed cells D Klimmeck, J Hansson, S Raffel, SY Vakhrushev, A Trumpp, J Krijgsveld Molecular & Cellular Proteomics 11 (8), 286-302, 2012 | 78 | 2012 |
| Quantitative proteomics reveals specific metabolic features of acute myeloid leukemia stem cells S Raffel, D Klimmeck, M Falcone, A Demir, A Pouya, P Zeisberger, C Lutz, ... Blood, The Journal of the American Society of Hematology 136 (13), 1507-1519, 2020 | 68 | 2020 |
| The rarity of ALDH+ cells is the key to separation of normal versus leukemia stem cells by ALDH activity in AML patients VT Hoang, EC Buss, W Wang, I Hoffmann, S Raffel, A Zepeda‐Moreno, ... International journal of cancer 137 (3), 525-536, 2015 | 54 | 2015 |
| Reduced hematopoietic stem cell frequency predicts outcome in acute myeloid leukemia W Wang, T Stiehl, S Raffel, VT Hoang, I Hoffmann, L Poisa-Beiro, ... Haematologica 102 (9), 1567, 2017 | 44 | 2017 |
| Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1 M Janssen, C Schmidt, PM Bruch, MF Blank, C Rohde, A Waclawiczek, ... Blood, The Journal of the American Society of Hematology 140 (24), 2594-2610, 2022 | 40 | 2022 |
| Antigen presentation safeguards the integrity of the hematopoietic stem cell pool P Hernández-Malmierca, D Vonficht, A Schnell, HJ Uckelmann, ... Cell Stem Cell 29 (5), 760-775. e10, 2022 | 38 | 2022 |
| miR-126 drives quiescence and self-renewal in leukemic stem cells S Raffel, A Trumpp Cancer cell 29 (2), 133-135, 2016 | 27 | 2016 |
| Combinatorial BCL2 family expression in acute myeloid leukemia stem cells predicts clinical response to azacitidine/venetoclax A Waclawiczek, AM Leppä, S Renders, K Stumpf, C Reyneri, B Betz, ... Cancer discovery 13 (6), 1408-1427, 2023 | 25 | 2023 |
| Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia S Beneyto-Calabuig, AK Merbach, JA Kniffka, M Antes, C Szu-Tu, ... Cell Stem Cell 30 (5), 706-721. e8, 2023 | 24 | 2023 |
| Differences between RNA and DNA due to RNA editing in temporal lobe epilepsy H Krestel, S Raffel, M von Lehe, C Jagella, S Moskau-Hartmann, A Becker, ... Neurobiology of disease 56, 66-73, 2013 | 22 | 2013 |
| The molecular signature of AML with increased ALDH activity suggests a stem cell origin R Blume, E Rempel, L Manta, BR Saeed, W Wang, S Raffel, O Ermakova, ... Leukemia & lymphoma 59 (9), 2201-2210, 2018 | 21 | 2018 |
| Prognostic value of low-level MRD in adult acute lymphoblastic leukemia detected by low-and high-throughput methods M Kotrová, J Koopmann, H Trautmann, N Alakel, J Beck, K Nachtkamp, ... Blood Advances 6 (10), 3006-3010, 2022 | 20 | 2022 |
