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Patrick Murphy
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Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice
PA Murphy, MTY Lam, X Wu, TN Kim, SM Vartanian, AW Bollen, ...
Proceedings of the National Academy of Sciences 105 (31), 10901-10906, 2008
1622008
Constitutively active Notch4 receptor elicits brain arteriovenous malformations through enlargement of capillary-like vessels
PA Murphy, TN Kim, L Huang, CM Nielsen, MT Lawton, RH Adams, ...
Proceedings of the National Academy of Sciences 111 (50), 18007-18012, 2014
1182014
Notch4 normalization reduces blood vessel size in arteriovenous malformations
PA Murphy, TN Kim, G Lu, AW Bollen, CB Schaffer, RA Wang
Science Translational Medicine 4 (117), 117ra8-117ra8, 2012
1032012
Endothelial Notch signaling is upregulated in human brain arteriovenous malformations and a mouse model of the disease
PA Murphy, G Lu, S Shiah, AW Bollen, RA Wang
Laboratory investigation 89 (9), 971-982, 2009
912009
Endothelial FN (Fibronectin) deposition by α5β1 integrins drives atherogenic inflammation
Z Al-Yafeai, A Yurdagul Jr, JM Peretik, M Alfaidi, PA Murphy, AW Orr
Arteriosclerosis, thrombosis, and vascular biology 38 (11), 2601-2614, 2018
832018
Tumor angiogenesis in the absence of fibronectin or its cognate integrin receptors
PA Murphy, S Begum, RO Hynes
PloS one 10 (3), e0120872, 2015
672015
Alternative splicing of endothelial fibronectin is induced by disturbed hemodynamics and protects against hemorrhage of the vessel wall
PA Murphy, RO Hynes
Arteriosclerosis, thrombosis, and vascular biology 34 (9), 2042-2050, 2014
582014
Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses
BH Kwan, EF Zhu, A Tzeng, HR Sugito, AA Eltahir, B Ma, MK Delaney, ...
Journal of Experimental Medicine 214 (6), 1679-1690, 2017
542017
AtheroSpectrum reveals novel macrophage foam cell gene signatures associated with atherosclerotic cardiovascular disease risk
C Li, L Qu, AJ Matz, PA Murphy, Y Liu, AW Manichaikul, D Aguiar, ...
Circulation 145 (3), 206-218, 2022
432022
Effect of magnetic field on the fermentation kinetics of Saccharomyces cerevisiae
A Deutmeyer, R Raman, P Murphy, S Pandey
Advances in Bioscience and Biotechnology 2 (04), 2011
402011
Alternative RNA splicing in the endothelium mediated in part by Rbfox2 regulates the arterial response to low flow
PA Murphy, VL Butty, PL Boutz, S Begum, AL Kimble, PA Sharp, ...
Elife 7, e29494, 2018
342018
Mouse models of cerebral arteriovenous malformation
CM Nielsen, L Huang, PA Murphy, MT Lawton, RA Wang
Stroke 47 (1), 293-300, 2016
292016
Interleukin 1-driven secretion of interleukin 2 is highly temperature-dependent.
HM Lederman, CR Brill, PA Murphy
Journal of immunology (Baltimore, Md.: 1950) 138 (11), 3808-3811, 1987
271987
Quantitative detection of messenger RNA by solution hybridization and enzyme immunoassay.
F Coutlee, EA Rubalcaba, RP Viscidi, JE Gern, PA Murphy, HM Lederman
Journal of Biological Chemistry 265 (20), 11601-11604, 1990
221990
Splice factor polypyrimidine tract-binding protein 1 (Ptbp1) primes endothelial inflammation in atherogenic disturbed flow conditions
JA Hensel, SAE Nicholas, AL Kimble, AS Nagpal, OMF Omar, JD Tyburski, ...
Proceedings of the National Academy of Sciences 119 (30), e2122227119, 2022
152022
Alternative splicing of FN (fibronectin) regulates the composition of the arterial wall under low flow
PA Murphy, N Jailkhani, SA Nicholas, AM Del Rosario, JL Balsbaugh, ...
Arteriosclerosis, thrombosis, and vascular biology 41 (1), e18-e32, 2021
132021
Direct CD137 costimulation of CD8 T cells promotes retention and innate-like function within nascent atherogenic foci
MM Xu, A Ménoret, SAE Nicholas, S Günther, EJ Sundberg, B Zhou, ...
American Journal of Physiology-Heart and Circulatory Physiology 316 (6 …, 2019
122019
Activated T-effector seeds: cultivating atherosclerotic plaque through alternative activation
MM Xu, PA Murphy, AT Vella
American Journal of Physiology-Heart and Circulatory Physiology 316 (6 …, 2019
102019
Loss of endothelial TDP-43 leads to blood brain barrier defects in mouse models of amyotrophic lateral sclerosis and frontotemporal dementia
A Cheemala, AL Kimble, JD Tyburski, NK Leclair, AR Zuberi, M Murphy, ...
bioRxiv, 2023
62023
A method for rapid flow-cytometric isolation of endothelial nuclei and RNA from archived frozen brain tissue
AL Kimble, J Silva, OM Omar, M Murphy, JA Hensel, SAE Nicholas, ...
Laboratory Investigation 102 (2), 204-211, 2022
62022
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