|Genome-wide association study identifies five loci associated with lung function|
E Repapi, I Sayers, LV Wain, PR Burton, T Johnson, M Obeidat, JH Zhao, ...
Nature genetics 42 (1), 36-44, 2010
|Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function|
MS Artigas, DW Loth, LV Wain, SA Gharib, M Obeidat, W Tang, G Zhai, ...
Nature genetics 43 (11), 1082-1090, 2011
|IL-33 is more potent than IL-25 in provoking IL-13–producing nuocytes (type 2 innate lymphoid cells) and airway contraction|
JL Barlow, S Peel, J Fox, V Panova, CS Hardman, A Camelo, C Bucks, ...
Journal of allergy and clinical immunology 132 (4), 933-941, 2013
|Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank|
LV Wain, N Shrine, S Miller, VE Jackson, I Ntalla, MS Artigas, ...
The Lancet Respiratory Medicine 3 (10), 769-781, 2015
|Variant LTC4 synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast|
AP Sampson, S Siddiqui, D Buchanan, PH Howarth, ST Holgate, ...
Thorax 55 (suppl 2), S28-S31, 2000
|Polymorphisms in the interleukin‐4 and interleukin‐4 receptor α chain genes confer susceptibility to asthma and atopy in a Caucasian population|
B Beghe, S Barton, S Rorke, Q Peng, I Sayers, T Gaunt, TP Keith, ...
Clinical & Experimental Allergy 33 (8), 1111-1117, 2003
|Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets|
LV Wain, N Shrine, MS Artigas, AM Erzurumluoglu, B Noyvert, ...
Nature genetics 49 (3), 416, 2017
|Genome-wide association study to identify genetic determinants of severe asthma|
YI Wan, NRG Shrine, MS Artigas, LV Wain, JD Blakey, MF Moffatt, A Bush, ...
Thorax 67 (9), 762-768, 2012
|Genetic risk factors for the development of allergic disease identified by genome‐wide association|
MA Portelli, E Hodge, I Sayers
Clinical & Experimental Allergy 45 (1), 21-31, 2015
|Evaluation of differentiated human bronchial epithelial cell culture systems for asthma research|
CE Stewart, EE Torr, NH Mohd Jamili, C Bosquillon, I Sayers
Journal of allergy 2012, 2012
|Genome-wide association analysis identifies six new loci associated with forced vital capacity|
DW Loth, MS Artigas, SA Gharib, LV Wain, N Franceschini, B Koch, ...
Nature genetics 46 (7), 669-677, 2014
|Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function|
M Soler Artigas, LV Wain, E Repapi, M Obeidat, I Sayers, PR Burton, ...
American journal of respiratory and critical care medicine 184 (7), 786-795, 2011
|Meta-analysis of genome-wide linkage studies of asthma and related traits|
S Denham, GH Koppelman, J Blakey, M Wjst, MA Ferreira, IP Hall, ...
Respiratory research 9 (1), 1-12, 2008
|Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study|
RJ Allen, J Porte, R Braybrooke, C Flores, TE Fingerlin, JM Oldham, ...
The Lancet Respiratory Medicine 5 (11), 869-880, 2017
|β2-adrenoceptor polymorphisms and asthma from childhood to middle age in the British 1958 birth cohort: a genetic association study|
IP Hall, JD Blakey, KA Al Balushi, A Wheatley, I Sayers, ME Pembrey, ...
The Lancet 368 (9537), 771-779, 2006
|Leukotriene pathway genetics and pharmacogenetics in allergy|
NP Duroudier, AS Tulah, I Sayers
Allergy 64 (6), 823-839, 2009
|New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries|
N Shrine, AL Guyatt, AM Erzurumluoglu, VE Jackson, BD Hobbs, ...
Nature genetics 51 (3), 481-493, 2019
|Allelic association and functional studies of promoter polymorphism in the leukotriene C4 synthase gene (LTC4S) in asthma|
I Sayers, S Barton, S Rorke, B Beghé, B Hayward, P Van Eerdewegh, ...
Thorax 58 (5), 417-424, 2003
|Polymorphisms in IL13 pathway genes in asthma and chronic obstructive pulmonary disease|
B Beghé, IP Hall, SG Parker, MF Moffatt, A Wardlaw, MJ Connolly, ...
Allergy 65 (4), 474-481, 2010
|Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation|
MS Artigas, LV Wain, S Miller, AK Kheirallah, JE Huffman, I Ntalla, ...
Nature communications 6 (1), 1-12, 2015