Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis V Makarov, G Manina, K Mikusova, U Möllmann, O Ryabova, ... Science 324 (5928), 801-804, 2009 | 839 | 2009 |
Role of mycobacterial efflux transporters in drug resistance: an unresolved question ED Rossi, JA Aínsa, G Riccardi FEMS microbiology reviews 30 (1), 36-52, 2006 | 410 | 2006 |
Rv2686c-Rv2687c-Rv2688c, an ABC Fluoroquinolone Efflux Pump in Mycobacterium tuberculosis MR Pasca, P Guglierame, F Arcesi, M Bellinzoni, E De Rossi, G Riccardi Antimicrobial agents and chemotherapy 48 (8), 3175-3178, 2004 | 247 | 2004 |
MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212 V La Rosa, G Poce, JO Canseco, S Buroni, MR Pasca, M Biava, RM Raju, ... Antimicrobial agents and chemotherapy 56 (1), 324-331, 2012 | 237 | 2012 |
Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis J Neres, F Pojer, E Molteni, LR Chiarelli, N Dhar, S Boy-Röttger, S Buroni, ... Science translational medicine 4 (150), 150ra121-150ra121, 2012 | 206 | 2012 |
mmpL7 Gene of Mycobacterium tuberculosis Is Responsible for Isoniazid Efflux in Mycobacterium smegmatis MR Pasca, P Guglierame, E De Rossi, F Zara, G Riccardi Antimicrobial agents and chemotherapy 49 (11), 4775-4777, 2005 | 190 | 2005 |
The Multidrug Transporters Belonging to Major Facilitator Superfamily (MFS) in Mycobacterium tuberculosis E De Rossi, P Arrigo, M Bellinzoni, PEA Silva, C Martín, JA Aínsa, ... Molecular medicine 8, 714-724, 2002 | 181 | 2002 |
mmr, a Mycobacterium tuberculosis Gene Conferring Resistance to Small Cationic Dyes and Inhibitors E De Rossi, M Branzoni, R Cantoni, A Milano, G Riccardi, O Ciferri Journal of bacteriology 180 (22), 6068-6071, 1998 | 142 | 1998 |
The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology TC Terwilliger, MS Park, GS Waldo, J Berendzen, LW Hung, CY Kim, ... Tuberculosis 83 (4), 223-249, 2003 | 137 | 2003 |
2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1 J Neres, RC Hartkoorn, LR Chiarelli, R Gadupudi, MR Pasca, G Mori, ... ACS chemical biology 10 (3), 705-714, 2015 | 125 | 2015 |
Efflux pump genes of the resistance-nodulation-division family in Burkholderia cenocepacia genome P Guglierame, MR Pasca, E De Rossi, S Buroni, P Arrigo, G Manina, ... BMC microbiology 6, 1-14, 2006 | 124 | 2006 |
Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection G Poce, RH Bates, S Alfonso, M Cocozza, GC Porretta, L Ballell, J Rullas, ... PloS one 8 (2), e56980, 2013 | 113 | 2013 |
1, 5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings M Biava, GC Porretta, G Poce, A De Logu, M Saddi, R Meleddu, F Manetti, ... Journal of medicinal chemistry 51 (12), 3644-3648, 2008 | 107 | 2008 |
Characterization of tetracycline resistance mediated by the efflux pump Tap from Mycobacterium fortuitum S Ramón-García, C Martín, JA Aínsa, E De Rossi Journal of antimicrobial chemotherapy 57 (2), 252-259, 2006 | 104 | 2006 |
Molecular Cloning and Functional Analysis of a Novel Tetracycline Resistance Determinant, tet(V), fromMycobacterium smegmatis E De Rossi, MCJ Blokpoel, R Cantoni, M Branzoni, G Riccardi, DB Young, ... Antimicrobial agents and chemotherapy 42 (8), 1931-1937, 1998 | 99 | 1998 |
1, 5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: Design, synthesis, and microbiological evaluation M Biava, GC Porretta, G Poce, A De Logu, R Meleddu, E De Rossi, ... European journal of medicinal chemistry 44 (11), 4734-4738, 2009 | 98 | 2009 |
Organization of the origins of replication of the chromosomes of Mycobacterium smegmatis, Mycobacterium leprae and Mycobacterium tuberculosis and isolation of a … L Salazar, H Fsihi, E de Rossi, G Riccardi, C Rios, ST Cole, HE Takiff Molecular microbiology 20 (2), 283-293, 1996 | 96 | 1996 |
Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance G Manina, M Bellinzoni, MR Pasca, J Neres, A Milano, ... Molecular microbiology 77 (5), 1172-1185, 2010 | 94 | 2010 |
Functional and genetic characterization of the tap efflux pump in Mycobacterium bovis BCG S Ramón-García, V Mick, E Dainese, C Martín, CJ Thompson, E De Rossi, ... Antimicrobial agents and chemotherapy 56 (4), 2074-2083, 2012 | 91 | 2012 |
Decaprenylphosphoryl-β-D-ribose 2'-epimerase from Mycobacterium tuberculosis is a magic drug target G Manina, M R Pasca, S Buroni, E De Rossi, G Riccardi Current medicinal chemistry 17 (27), 3099-3108, 2010 | 90 | 2010 |