| Imaging intracellular fluorescent proteins at nanometer resolution E Betzig, GH Patterson, R Sougrat, OW Lindwasser, S Olenych, ... science 313 (5793), 1642-1645, 2006 | 9855 | 2006 |
| Near-field optics: microscopy, spectroscopy, and surface modification beyond the diffraction limit E Betzig, JK Trautman Science 257 (5067), 189-195, 1992 | 2623 | 1992 |
| Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution BC Chen, WR Legant, K Wang, L Shao, DE Milkie, MW Davidson, ... Science 346 (6208), 1257998, 2014 | 1955 | 2014 |
| Single molecules observed by near-field scanning optical microscopy E Betzig, RJ Chichester Science 262 (5138), 1422-1425, 1993 | 1952 | 1993 |
| High-density mapping of single-molecule trajectories with photoactivated localization microscopy S Manley, JM Gillette, GH Patterson, H Shroff, HF Hess, E Betzig, ... Nature methods 5 (2), 155-157, 2008 | 1301 | 2008 |
| Rapid three-dimensional isotropic imaging of living cells using Bessel beam plane illumination TA Planchon, L Gao, DE Milkie, MW Davidson, JA Galbraith, CG Galbraith, ... Nature methods 8 (5), 417-423, 2011 | 1210 | 2011 |
| Near‐field magneto‐optics and high density data storage E Betzig, JK Trautman, R Wolfe, EM Gyorgy, PL Finn, MH Kryder, ... Applied Physics Letters 61 (2), 142-144, 1992 | 1175 | 1992 |
| Live-cell photoactivated localization microscopy of nanoscale adhesion dynamics H Shroff, CG Galbraith, JA Galbraith, E Betzig Nature methods 5 (5), 417-423, 2008 | 999 | 2008 |
| Applying systems-level spectral imaging and analysis to reveal the organelle interactome AM Valm, S Cohen, WR Legant, J Melunis, U Hershberg, E Wait, ... Nature 546 (7656), 162-167, 2017 | 927 | 2017 |
| Extended-resolution structured illumination imaging of endocytic and cytoskeletal dynamics D Li, L Shao, BC Chen, X Zhang, M Zhang, B Moses, DE Milkie, JR Beach, ... Science 349 (6251), aab3500, 2015 | 729 | 2015 |
| Near-field spectroscopy of the quantum constituents of a luminescent system HF Hess, E Betzig, TD Harris, LN Pfeiffer, KW West Science 264 (5166), 1740-1745, 1994 | 696 | 1994 |
| Adaptive optics via pupil segmentation for high-resolution imaging in biological tissues N Ji, DE Milkie, E Betzig Nature methods 7 (2), 141-147, 2010 | 642 | 2010 |
| Near-field spectroscopy of single molecules at room temperature JK Trautman, JJ Macklin, LE Brus, E Betzig Nature 369 (6475), 40-42, 1994 | 616 | 1994 |
| Near field scanning optical microscopy (NSOM): development and biophysical applications E Betzig, A Lewis, A Harootunian, M Isaacson, E Kratschmer Biophysical journal 49 (1), 269-279, 1986 | 616 | 1986 |
| Dual-color superresolution imaging of genetically expressed probes within individual adhesion complexes H Shroff, CG Galbraith, JA Galbraith, H White, J Gillette, S Olenych, ... Proceedings of the National Academy of Sciences 104 (51), 20308-20313, 2007 | 602 | 2007 |
| Single-molecule dynamics of enhanceosome assembly in embryonic stem cells J Chen, Z Zhang, L Li, BC Chen, A Revyakin, B Hajj, W Legant, M Dahan, ... Cell 156 (6), 1274-1285, 2014 | 591 | 2014 |
| Proposed method for molecular optical imaging E Betzig Optics letters 20 (3), 237-239, 1995 | 540 | 1995 |
| Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms TL Liu, S Upadhyayula, DE Milkie, V Singh, K Wang, IA Swinburne, ... Science 360 (6386), eaaq1392, 2018 | 528 | 2018 |
| Visualizing intracellular organelle and cytoskeletal interactions at nanoscale resolution on millisecond timescales Y Guo, D Li, S Zhang, Y Yang, JJ Liu, X Wang, C Liu, DE Milkie, ... Cell 175 (5), 1430-1442. e17, 2018 | 508 | 2018 |
| Imaging live-cell dynamics and structure at the single-molecule level Z Liu, LD Lavis, E Betzig Molecular cell 58 (4), 644-659, 2015 | 499 | 2015 |
