| Intraoperative protective mechanical ventilation for prevention of postoperative pulmonary complications: a comprehensive review of the role of tidal volume, positive end … A Güldner, T Kiss, A Serpa Neto, SNT Hemmes, J Canet, PM Spieth, ... Anesthesiology 123 (3), 692-713, 2015 | 455 | 2015 |
| Randomized controlled trials–a matter of design PM Spieth, AS Kubasch, AI Penzlin, BMW Illigens, K Barlinn, T Siepmann Neuropsychiatric disease and treatment, 1341-1349, 2016 | 385 | 2016 |
| Mechanical stress induces lung fibrosis by epithelial–mesenchymal transition NE Cabrera-Benitez, M Parotto, M Post, B Han, PM Spieth, WE Cheng, ... Critical care medicine 40 (2), 510-517, 2012 | 201 | 2012 |
| Mechanical ventilation–associated lung fibrosis in acute respiratory distress syndrome: a significant contributor to poor outcome NE Cabrera-Benitez, JG Laffey, M Parotto, PM Spieth, J Villar, H Zhang, ... Anesthesiology 121 (1), 189-198, 2014 | 197 | 2014 |
| Variable tidal volumes improve lung protective ventilation strategies in experimental lung injury PM Spieth, AR Carvalho, P Pelosi, C Hoehn, C Meissner, M Kasper, ... American journal of respiratory and critical care medicine 179 (8), 684-693, 2009 | 183 | 2009 |
| Epidemiology, practice of ventilation and outcome for patients at increased risk of postoperative pulmonary complications: LAS VEGAS-an observational study in 29 countries MJ Schultz, SNT Hemmes, AS Neto, JM Binnekade, J Canet, ... European journal of anaesthesiology, 2017 | 143 | 2017 |
| Noisy pressure support ventilation: a pilot study on a new assisted ventilation mode in experimental lung injury MG de Abreu, PM Spieth, P Pelosi, AR Carvalho, C Walter, ... Critical care medicine 36 (3), 818-827, 2008 | 133 | 2008 |
| Molecular dynamics of lipopolysaccharide-induced lung injury in rodents H Domscheit, MA Hegeman, N Carvalho, PM Spieth Frontiers in physiology 11, 36, 2020 | 130 | 2020 |
| Mechanical stress and the induction of lung fibrosis via the midkine signaling pathway R Zhang, Y Pan, V Fanelli, S Wu, AA Luo, D Islam, B Han, P Mao, ... American journal of respiratory and critical care medicine 192 (3), 315-323, 2015 | 122 | 2015 |
| Circadian rhythms: from basic mechanisms to the intensive care unit MC Chan, PM Spieth, K Quinn, M Parotto, H Zhang, AS Slutsky Critical care medicine 40 (1), 246-253, 2012 | 113 | 2012 |
| Ability of dynamic airway pressure curve profile and elastance for positive end-expiratory pressure titration AR Carvalho, PM Spieth, P Pelosi, MF Vidal Melo, T Koch, FC Jandre, ... Intensive care medicine 34, 2291-2299, 2008 | 102 | 2008 |
| Pressure support improves oxygenation and lung protection compared to pressure-controlled ventilation and is further improved by random variation of pressure support PM Spieth, AR Carvalho, A Güldner, M Kasper, R Schubert, NC Carvalho, ... Critical care medicine 39 (4), 746-755, 2011 | 98 | 2011 |
| Effects of different levels of pressure support variability in experimental lung injury PM Spieth, AR Carvalho, A Güldner, P Pelosi, O Kirichuk, T Koch, ... The Journal of the American Society of Anesthesiologists 110 (2), 342-350, 2009 | 90 | 2009 |
| Results of the CAPSID randomized trial for high-dose convalescent plasma in patients with severe COVID-19 S Körper, M Weiss, D Zickler, T Wiesmann, K Zacharowski, VM Corman, ... The Journal of clinical investigation 131 (20), 2021 | 80 | 2021 |
| Mechanotransduction in the lungs. PM Spieth, T Bluth, M Gama De Abreu, A Bacelis, AE Goetz, R Kiefmann Minerva anestesiologica 80 (8), 933-941, 2013 | 77 | 2013 |
| Increased risk of acute stroke among patients with severe COVID‐19: a multicenter study and meta‐analysis T Siepmann, A Sedghi, E Simon, S Winzer, J Barlinn, K De With, L Mirow, ... European Journal of Neurology 28 (1), 238-247, 2021 | 73 | 2021 |
| Personalized medicine for ARDS: the 2035 research agenda JR Beitler, EC Goligher, M Schmidt, PM Spieth, A Zanella, ... Intensive care medicine 42, 756-767, 2016 | 67 | 2016 |
| Distribution of regional lung aeration and perfusion during conventional and noisy pressure support ventilation in experimental lung injury AR Carvalho, PM Spieth, A Güldner, M Cuevas, NC Carvalho, A Beda, ... Journal of applied physiology 110 (4), 1083-1092, 2011 | 65 | 2011 |
| Effects of anesthetic regimes on inflammatory responses in a rat model of acute lung injury S Fortis, PM Spieth, WY Lu, M Parotto, JJ Haitsma, AS Slutsky, N Zhong, ... Intensive care medicine 38, 1548-1555, 2012 | 64 | 2012 |
| Higher levels of spontaneous breathing induce lung recruitment and reduce global stress/strain in experimental lung injury A Güldner, A Braune, N Carvalho, A Beda, S Zeidler, B Wiedemann, ... Anesthesiology 120 (3), 673-682, 2014 | 63 | 2014 |
