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Aaron McGrath
Aaron McGrath
Senior Scientist, Takeda Pharmaceuticals
Bestätigte E-Mail-Adresse bei takeda.com
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Zitiert von
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Jahr
Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein
P Szewczyk, H Tao, AP McGrath, M Villaluz, SD Rees, SC Lee, R Doshi, ...
Acta Crystallographica Section D: Biological Crystallography 71 (3), 732-741, 2015
1802015
Structure and inhibition of human diamine oxidase
AP McGrath, KM Hilmer, CA Collyer, EM Shepard, BO Elmore, DE Brown, ...
Biochemistry 48 (41), 9810-9822, 2009
1182009
Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure
SCT Nicklisch, SD Rees, AP McGrath, T Gökirmak, LT Bonito, ...
Science advances 2 (4), e1600001, 2016
1102016
The zinc fingers of the SR-like protein ZRANB2 are single-stranded RNA-binding domains that recognize 5′ splice site-like sequences
FE Loughlin, RE Mansfield, PM Vaz, AP McGrath, S Setiyaputra, ...
Proceedings of the National Academy of Sciences 106 (14), 5581-5586, 2009
1062009
Cryo-EM structure of OSCA1.2 from Oryza sativa elucidates the mechanical basis of potential membrane hyperosmolality gating
K Maity, JM Heumann, AP McGrath, NJ Kopcho, PK Hsu, CW Lee, ...
Proceedings of the National Academy of Sciences 116 (28), 14309-14318, 2019
902019
Mass spectrometry-based visualization of molecules associated with human habitats
D Petras, LF Nothias, RA Quinn, T Alexandrov, N Bandeira, A Bouslimani, ...
Analytical chemistry 88 (22), 10775-10784, 2016
522016
Functional characterization and discovery of modulators of SbMATE, the agronomically important aluminium tolerance transporter from Sorghum bicolor
R Doshi, AP McGrath, M Piñeros, P Szewczyk, DM Garza, LV Kochian, ...
Scientific reports 7 (1), 17996, 2017
312017
Structure and Activity of Aspergillus nidulans Copper Amine Oxidase
AP McGrath, SM Mithieux, CA Collyer, JG Bakhuis, M van den Berg, ...
Biochemistry 50 (25), 5718-5730, 2011
282011
A new crystal form of human vascular adhesion protein 1
K Ernberg, AP McGrath, TS Peat, TE Adams, X Xiao, T Pham, J Newman, ...
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010
262010
Structural basis of interprotein electron transfer in bacterial sulfite oxidation
AP McGrath, EL Laming, GP Casas Garcia, M Kvansakul, JM Guss, ...
Elife 4, e09066, 2015
242015
Correlation of active site metal content in human diamine oxidase with trihydroxyphenylalanine quinone cofactor biogenesis
AP McGrath, T Caradoc-Davies, CA Collyer, JM Guss
Biochemistry 49 (38), 8316-8324, 2010
232010
The RhoGAP protein ARHGAP18/SENEX localizes to microtubules and regulates their stability in endothelial cells
MD Lovelace, EE Powter, PR Coleman, Y Zhao, A Parker, GH Chang, ...
Molecular biology of the cell 28 (8), 1066-1078, 2017
212017
The structural basis of bacterial manganese import
SL Neville, J Sjöhamn, JA Watts, H MacDermott-Opeskin, SJ Fairweather, ...
Science Advances 7 (32), eabg3980, 2021
202021
A new crystal form of human diamine oxidase
AP McGrath, KM Hilmer, CA Collyer, DM Dooley, JM Guss
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010
162010
Molecular mechanism of the wake-promoting agent TAK-925
J Yin, Y Kang, AP McGrath, K Chapman, M Sjodt, E Kimura, A Okabe, ...
Nature communications 13 (1), 2902, 2022
152022
Structure of an atypical FeoB G-domain reveals a putative domain-swapped dimer
CN Deshpande, AP McGrath, J Font, AP Guilfoyle, MJ Maher, M Jormakka
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013
142013
The uncharacterized gene EVE contributes to vessel element dimensions in Populus
CL Ribeiro, D Conde, KM Balmant, C Dervinis, MG Johnson, AP McGrath, ...
Proceedings of the National Academy of Sciences 117 (9), 5059-5066, 2020
132020
The X-ray crystal structure of a pseudoazurin from Sinorhizobium meliloti
EM Laming, AP McGrath, JM Guss, U Kappler, MJ Maher
Journal of Inorganic Biochemistry 115, 148-154, 2012
112012
The central active site arginine in sulfite oxidizing enzymes alters kinetic properties by controlling electron transfer and redox interactions
JC Hsiao, AP McGrath, L Kielmann, P Kalimuthu, F Darain, PV Bernhardt, ...
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1859 (1), 19-27, 2018
102018
Transporter-interfering chemicals inhibit P-glycoprotein of yellowfin tuna (Thunnus albacares)
SCT Nicklisch, AK Pouv, SD Rees, AP McGrath, G Chang, A Hamdoun
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2021
92021
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