Lars Nitschke
Lars Nitschke
Lehrstuhl Genetik, University of Erlangen
Bestätigte E-Mail-Adresse bei fau.de
TitelZitiert vonJahr
CD22 is a negative regulator of B-cell receptor signalling
L Nitschke, R Carsetti, B Ocker, G Köhler, MC Lamers
Current Biology 7 (2), 133-143, 1997
4211997
B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity
LI Pao, KP Lam, JM Henderson, JL Kutok, M Alimzhanov, L Nitschke, ...
Immunity 27 (1), 35-48, 2007
2122007
The role of CD22 and other inhibitory co-receptors in B-cell activation
L Nitschke
Current opinion in immunology 17 (3), 290-297, 2005
2062005
The murine inhibitory receptor mSiglec‐E is expressed broadly on cells of the innate immune system whereas mSiglec‐F is restricted to eosinophils
JQ Zhang, B Biedermann, L Nitschke, PR Crocker
European journal of immunology 34 (4), 1175-1184, 2004
1812004
CD22 and Siglec‐G: B‐cell inhibitory receptors with distinct functions
L Nitschke
Immunological reviews 230 (1), 128-143, 2009
1722009
The ligand-binding domain of CD22 is needed for inhibition of the B cell receptor signal, as demonstrated by a novel human CD22-specific inhibitor compound
S Kelm, J Gerlach, R Brossmer, CP Danzer, L Nitschke
Journal of Experimental Medicine 195 (9), 1207-1213, 2002
1672002
Compensation between Vav-1 and Vav-2 in B cell development and antigen receptor signaling
K Tedford, L Nitschke, I Girkontaite, A Charlesworth, G Chan, V Sakk, ...
Nature immunology 2 (6), 548, 2001
1662001
Siglec-G is a B1 cell–inhibitory receptor that controls expansion and calcium signaling of the B1 cell population
A Hoffmann, S Kerr, J Jellusova, J Zhang, F Weisel, U Wellmann, ...
Nature immunology 8 (7), 695, 2007
1572007
Reduction of marginal zone B cells in CD22‐deficient mice
T Samardzic, D Marinkovic, CP Danzer, J Gerlach, L Nitschke, T Wirth
European journal of immunology 32 (2), 561-567, 2002
1382002
Effect of transmembrane and cytoplasmic domains of IgE on the IgE response
G Achatz, L Nitschke, MC Lamers
Science 276 (5311), 409-411, 1997
1361997
Immunoglobulin D-deficient mice can mount normal immune responses to thymus-independent and-dependent antigens.
L Nitschke, MH Kosco, G Köhler, MC Lamers
Proceedings of the National Academy of Sciences 90 (5), 1887-1891, 1993
1281993
Identification of CD22 ligands on bone marrow sinusoidal endothelium implicated in CD22-dependent homing of recirculating B cells
L Nitschke, H Floyd, DJP Ferguson, PR Crocker
Journal of Experimental Medicine 189 (9), 1513-1518, 1999
1211999
CD22× Siglec-G double-deficient mice have massively increased B1 cell numbers and develop systemic autoimmunity
J Jellusova, U Wellmann, K Amann, TH Winkler, L Nitschke
The Journal of Immunology 184 (7), 3618-3627, 2010
1122010
The sialic acids V. N-acyl-D-glucosamine 2-epimerase
S Ghosh, S Roseman
Journal of Biological Chemistry 240 (4), 1531-1536, 1965
1101965
Molecular interactions regulate BCR signal inhibition by CD22 and CD72
L Nitschke, T Tsubata
Trends in immunology 25 (10), 543-550, 2004
1022004
IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Igα/β
A Waisman, M Kraus, J Seagal, S Ghosh, D Melamed, J Song, Y Sasaki, ...
Journal of Experimental Medicine 204 (4), 747-758, 2007
982007
NFATc1 affects mouse splenic B cell function by controlling the calcineurin–NFAT signaling network
S Bhattacharyya, J Deb, AK Patra, DAT Pham, W Chen, M Vaeth, ...
Journal of Experimental Medicine 208 (4), 823-839, 2011
932011
The Yaa mutation promoting murine lupus causes defective development of marginal zone B cells
H Amano, E Amano, T Moll, D Marinkovic, N Ibnou-Zekri, E Martinez-Soría, ...
The Journal of Immunology 170 (5), 2293-2301, 2003
932003
Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production
GC Ippolito, RL Schelonka, M Zemlin, II Ivanov, R Kobayashi, C Zemlin, ...
Journal of Experimental Medicine 203 (6), 1567-1578, 2006
892006
Naive CD8 T-cells initiate spontaneous autoimmunity to a sequestered model antigen of the central nervous system
SY Na, Y Cao, C Toben, L Nitschke, C Stadelmann, R Gold, A Schimpl, ...
Brain 131 (9), 2353-2365, 2008
832008
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