Alternative isoform regulation in human tissue transcriptomes ET Wang, R Sandberg, S Luo, I Khrebtukova, L Zhang, C Mayr, ... Nature 456 (7221), 470-476, 2008 | 5954 | 2008 |
Analysis and design of RNA sequencing experiments for identifying isoform regulation Y Katz, ET Wang, EM Airoldi, CB Burge Nature methods 7 (12), 1009-1015, 2010 | 1552 | 2010 |
An abundance of ubiquitously expressed genes revealed by tissue transcriptome sequence data D Ramsköld, ET Wang, CB Burge, R Sandberg PLoS computational biology 5 (12), e1000598, 2009 | 987 | 2009 |
Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2 KM Parmar, HB Larman, G Dai, Y Zhang, ET Wang, SN Moorthy, JR Kratz, ... The Journal of clinical investigation 116 (1), 49-58, 2006 | 849 | 2006 |
Transcriptome-wide regulation of pre-mRNA splicing and mRNA localization by muscleblind proteins ET Wang, NAL Cody, S Jog, M Biancolella, TT Wang, DJ Treacy, S Luo, ... Cell 150 (4), 710-724, 2012 | 544 | 2012 |
MBNL proteins repress ES-cell-specific alternative splicing and reprogramming H Han, M Irimia, PJ Ross, HK Sung, B Alipanahi, L David, A Golipour, ... Nature 498 (7453), 241-245, 2013 | 356 | 2013 |
Biomechanical forces in atherosclerosis-resistant vascular regions regulate endothelial redox balance via phosphoinositol 3-kinase/Akt-dependent activation of Nrf2 G Dai, S Vaughn, Y Zhang, ET Wang, G Garcia-Cardena, MA Gimbrone Jr Circulation research 101 (7), 723-733, 2007 | 278 | 2007 |
Distal alternative last exons localize mRNAs to neural projections JM Taliaferro, M Vidaki, R Oliveira, S Olson, L Zhan, T Saxena, ET Wang, ... Molecular cell 61 (6), 821-833, 2016 | 274 | 2016 |
Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics JE Dahlman, KJ Kauffman, Y Xing, TE Shaw, FF Mir, CC Dlott, R Langer, ... Proceedings of the National Academy of Sciences 114 (8), 2060-2065, 2017 | 263 | 2017 |
Molecular mechanisms underlying nucleotide repeat expansion disorders I Malik, CP Kelley, ET Wang, PK Todd Nature reviews Molecular cell biology 22 (9), 589-607, 2021 | 243 | 2021 |
Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins ET Wang, AJ Ward, JM Cherone, J Giudice, TT Wang, DJ Treacy, ... Genome research 25 (6), 858-871, 2015 | 220 | 2015 |
Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy F Freyermuth, F Rau, Y Kokunai, T Linke, C Sellier, M Nakamori, Y Kino, ... Nature communications 7 (1), 11067, 2016 | 194 | 2016 |
Quantitative visualization of alternative exon expression from RNA-seq data Y Katz, ET Wang, J Silterra, S Schwartz, B Wong, H Thorvaldsdottir, ... Bioinformatics 31 (14), 2400-2402, 2015 | 185 | 2015 |
Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development J Giudice, Z Xia, ET Wang, MA Scavuzzo, AJ Ward, A Kalsotra, W Wang, ... Nature communications 5 (1), 3603, 2014 | 173 | 2014 |
Global regulation of alternative splicing during myogenic differentiation CS Bland, ET Wang, A Vu, MP David, JC Castle, JM Johnson, CB Burge, ... Nucleic acids research 38 (21), 7651-7664, 2010 | 170 | 2010 |
Mice with endogenous TDP‐43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis P Fratta, P Sivakumar, J Humphrey, K Lo, T Ricketts, H Oliveira, ... The EMBO journal 37 (11), e98684, 2018 | 166 | 2018 |
Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer MG Costales, H Aikawa, Y Li, JL Childs-Disney, D Abegg, DG Hoch, ... Proceedings of the National Academy of Sciences 117 (5), 2406-2411, 2020 | 151 | 2020 |
Design of a bioactive small molecule that targets the myotonic dystrophy type 1 RNA via an RNA motif–ligand database and chemical similarity searching R Parkesh, JL Childs-Disney, M Nakamori, A Kumar, E Wang, T Wang, ... Journal of the American Chemical Society 134 (10), 4731-4742, 2012 | 150 | 2012 |
Myotonic dystrophy: disease repeat range, penetrance, age of onset, and relationship between repeat size and phenotypes K Yum, ET Wang, A Kalsotra Current opinion in genetics & development 44, 30-37, 2017 | 141 | 2017 |
Splice site strength–dependent activity and genetic buffering by poly-G runs X Xiao, Z Wang, M Jang, R Nutiu, ET Wang, CB Burge Nature structural & molecular biology 16 (10), 1094-1100, 2009 | 139 | 2009 |