Johannes Kornhuber
Johannes Kornhuber
Professor for Psychiatry, University of Erlangen
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Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
D Harold, R Abraham, P Hollingworth, R Sims, A Gerrish, ML Hamshere, ...
Nature genetics 41 (10), 1088, 2009
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
P Hollingworth, D Harold, R Sims, A Gerrish, JC Lambert, ...
Nature genetics 43 (5), 429, 2011
Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis
WJ Jansen, R Ossenkoppele, DL Knol, BM Tijms, P Scheltens, ...
Jama 313 (19), 1924-1938, 2015
Elevated levels of tau-protein in cerebrospinal fluid of patients with Creutzfeldt–Jakob disease
M Otto, J Wiltfang, H Tumani, I Zerr, M Lantsch, J Kornhuber, T Weber, ...
Neuroscience letters 225 (3), 210-212, 1997
Analysis of shared heritability in common disorders of the brain
V Anttila, B Bulik-Sullivan, HK Finucane, RK Walters, J Bras, L Duncan, ...
Science 360 (6395), eaap8757, 2018
Therapeutic approaches to Alzheimer's disease
HW Klafki, M Staufenbiel, J Kornhuber, J Wiltfang
Brain 129 (11), 2840-2855, 2006
Aminoadamantanes as NMDA receptor antagonists and antiparkinsonian agents—preclinical studies
W Danysz, CG Parsons, J Kornhuber, WJ Schmidt, G Quack
Neuroscience & Biobehavioral Reviews 21 (4), 455-468, 1997
Effects of the 1-amino-adamantanes at the MK-801-binding site of the NMDA-receptor-gated ion channel: a human postmortem brain study
J Kornhuber, J Bormann, M Hübers, K Rusche, P Riederer
European Journal of Pharmacology: Molecular Pharmacology 206 (4), 297-300, 1991
Highly conserved and disease‐specific patterns of carboxyterminally truncated Aβ peptides 1–37/38/39 in addition to 1–40/42 in Alzheimer's disease and in patients with chronic …
J Wiltfang, H Esselmann, M Bibl, A Smirnov, M Otto, S Paul, B Schmidt, ...
Journal of neurochemistry 81 (3), 481-496, 2002
Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease
L Jones, PA Holmans, ML Hamshere, D Harold, V Moskvina, D Ivanov, ...
PloS one 5 (11), e13950, 2010
Memantine displaces [3H] MK-801 at therapeutic concentrations in postmortem human frontal cortex.
J Kornhuber, J Bormann, W Retz, M Hübers, P Riederer
European journal of pharmacology 166 (3), 589, 1989
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ...
Nature genetics 49 (9), 1373, 2017
Neurochemical diagnosis of Alzheimer’s dementia by CSF Aβ42, Aβ42/Aβ40 ratio and total tau
P Lewczuk, H Esselmann, M Otto, JM Maler, AW Henkel, MK Henkel, ...
Neurobiology of aging 25 (3), 273-281, 2004
(3H]MK-801 binding sites in postmortem brain regions of schizophrenic patients
J Kornhuber, F Mack-Burkhardt, P Riederer, GF Hebenstreit, GP Reynolds, ...
Journal of Neural Transmission 77 (2-3), 231-236, 1989
Psychotogenicity and N-methyl-D-aspartate receptor antagonism: implications for neuroprotective pharmacotherapy
J Kornhuber, M Weller
Biological psychiatry 41 (2), 135-144, 1997
SPECT imaging of dopamine and serotonin transporters with [123I]β-CIT. Binding kinetics in the human brain
T Brücke, J Kornhuber, P Angelberger, S Asenbaum, H Frassine, ...
Journal of Neural Transmission/General Section JNT 94 (2), 137-146, 1993
Amyloid β peptide ratio 42/40 but not Aβ42 correlates with phospho‐Tau in patients with low‐and high‐CSF Aβ40 load
J Wiltfang, H Esselmann, M Bibl, M Hüll, H Hampel, H Kessler, L Frölich, ...
Journal of neurochemistry 101 (4), 1053-1059, 2007
Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications
J Kornhuber, P Tripal, M Reichel, C Mühle, C Rhein, M Muehlbacher, ...
Cellular Physiology and Biochemistry 26 (1), 9-20, 2010
BOLD fMRI deactivation of limbic and temporal brain structures and mood enhancing effect by transcutaneous vagus nerve stimulation
T Kraus, K Hösl, O Kiess, A Schanze, J Kornhuber, C Forster
Journal of neural transmission 114 (11), 1485-1493, 2007
Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs
E Gulbins, M Palmada, M Reichel, A Lüth, C Böhmer, D Amato, CP Müller, ...
Nature medicine 19 (7), 934, 2013
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