| Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca2+ channel complex JM Brittain, DB Duarte, SM Wilson, W Zhu, C Ballard, PL Johnson, N Liu, ... Nature medicine 17 (7), 822-829, 2011 | 240 | 2011 |
| Effective inhibition of SARS-CoV-2 entry by heparin and enoxaparin derivatives R Tandon, JS Sharp, F Zhang, VH Pomin, NM Ashpole, D Mitra, ... Journal of Virology 95 (3), 10.1128/jvi. 01987-20, 2021 | 228 | 2021 |
| Growth hormone, insulin-like growth factor-1 and the aging brain NM Ashpole, JE Sanders, EL Hodges, H Yan, WE Sonntag Experimental gerontology 68, 76-81, 2015 | 205 | 2015 |
| Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1. 5 gating by multiple phosphorylation sites NM Ashpole, AW Herren, KS Ginsburg, JD Brogan, DE Johnson, ... Journal of Biological Chemistry 287 (24), 19856-19869, 2012 | 205 | 2012 |
| Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase P Toth, S Tarantini, Z Tucsek, NM Ashpole, D Sosnowska, T Gautam, ... American Journal of Physiology-Heart and Circulatory Physiology 306 (3 …, 2014 | 203 | 2014 |
| The effects of exercise on memory function among young to middle-aged adults: systematic review and recommendations for future research PD Loprinzi, E Frith, MK Edwards, E Sng, N Ashpole American Journal of Health Promotion 32 (3), 691-704, 2018 | 159 | 2018 |
| CaMKII in cerebral ischemia SJ Coultrap, RS Vest, NM Ashpole, A Hudmon, KU Bayer Acta Pharmacologica Sinica 32 (7), 861-872, 2011 | 155 | 2011 |
| IGF‐1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging P Toth, S Tarantini, NM Ashpole, Z Tucsek, GL Milne, NM Valcarcel‐Ares, ... Aging cell 14 (6), 1034-1044, 2015 | 139 | 2015 |
| Excitotoxic neuroprotection and vulnerability with CaMKII inhibition NM Ashpole, A Hudmon Molecular and Cellular Neuroscience 46 (4), 720-730, 2011 | 128 | 2011 |
| IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan NM Ashpole, S Logan, A Yabluchanskiy, MC Mitschelen, H Yan, JA Farley, ... Geroscience 39, 129-145, 2017 | 127 | 2017 |
| Insulin-like growth factor-1 in CNS and cerebrovascular aging WE Sonntag, F Deak, N Ashpole, P Toth, A Csiszar, W Freeman, ... Frontiers in aging neuroscience 5, 27, 2013 | 126 | 2013 |
| Calcium/calmodulin-dependent protein kinase II (CaMKII) inhibition induces neurotoxicity via dysregulation of glutamate/calcium signaling and hyperexcitability NM Ashpole, W Song, T Brustovetsky, EA Engleman, N Brustovetsky, ... Journal of Biological Chemistry 287 (11), 8495-8506, 2012 | 123 | 2012 |
| Whole brain radiation-induced vascular cognitive impairment: mechanisms and implications JP Warrington, N Ashpole, A Csiszar, YW Lee, Z Ungvari, WE Sonntag Journal of vascular research 50 (6), 445-457, 2013 | 111 | 2013 |
| Neuroprotection against traumatic brain injury by a peptide derived from the collapsin response mediator protein 2 (CRMP2) JM Brittain, L Chen, SM Wilson, T Brustovetsky, X Gao, NM Ashpole, ... Journal of Biological Chemistry 286 (43), 37778-37792, 2011 | 98 | 2011 |
| Insulin‐like growth factor 1 deficiency exacerbates hypertension‐induced cerebral microhemorrhages in mice, mimicking the aging phenotype S Tarantini, NM Valcarcel‐Ares, A Yabluchanskiy, Z Springo, GA Fulop, ... Aging Cell 16 (3), 469-479, 2017 | 88 | 2017 |
| Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular … S Tarantini, Z Tucsek, MN Valcarcel-Ares, P Toth, T Gautam, CB Giles, ... Age 38, 273-289, 2016 | 83 | 2016 |
| Aging impairs myogenic adaptation to pulsatile pressure in mouse cerebral arteries Z Springo, P Toth, S Tarantini, NM Ashpole, Z Tucsek, WE Sonntag, ... Journal of Cerebral Blood Flow & Metabolism 35 (4), 527-530, 2015 | 68 | 2015 |
| Target-specific support vector machine scoring in structure-based virtual screening: computational validation, in vitro testing in kinases, and effects on lung cancer cell … L Li, M Khanna, I Jo, F Wang, NM Ashpole, A Hudmon, SO Meroueh Journal of chemical information and modeling 51 (4), 755-759, 2011 | 67 | 2011 |
| Small molecule inhibitors of PSD95-nNOS protein–protein interactions as novel analgesics WH Lee, Z Xu, NM Ashpole, A Hudmon, PM Kulkarni, GA Thakur, YY Lai, ... Neuropharmacology 97, 464-475, 2015 | 64 | 2015 |
| Loss of calcium/calmodulin-dependent protein kinase II activity in cortical astrocytes decreases glutamate uptake and induces neurotoxic release of ATP NM Ashpole, AR Chawla, MP Martin, T Brustovetsky, N Brustovetsky, ... Journal of Biological Chemistry 288 (20), 14599-14611, 2013 | 60 | 2013 |
