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Rukmini Kumar
Rukmini Kumar
Chief Scientist
Verified email at vantage-research.net - Homepage
Title
Cited by
Cited by
Year
The dynamics of acute inflammation
R Kumar, G Clermont, Y Vodovotz, CC Chow
Journal of Theoretical Biology 230 (2), 145-155, 2004
3452004
The acute inflammatory response in diverse shock states
CC Chow, G Clermont, R Kumar, C Lagoa, Z Tawadrous, D Gallo, ...
Shock 24 (1), 74-84, 2005
2152005
In silico design of clinical trials: a method coming of age
G Clermont, J Bartels, R Kumar, G Constantine, Y Vodovotz, C Chow
Critical care medicine 32 (10), 2061-2070, 2004
1922004
In silico models of acute inflammation in animals
Y Vodovotz, CC Chow, J Bartels, C Lagoa, JM Prince, RM Levy, R Kumar, ...
Shock 26 (3), 235-244, 2006
1242006
In vitro to in vivo extrapolation and species response comparisons for drug-induced liver injury (DILI) using DILIsym™: a mechanistic, mathematical model of DILI
BA Howell, Y Yang, R Kumar, JL Woodhead, AH Harrill, HJ Clewell, ...
Journal of pharmacokinetics and pharmacodynamics 39 (5), 527-541, 2012
932012
A mathematical simulation of the inflammatory response to anthrax infection
R Kumar, CC Chow, JD Bartels, G Clermont, Y Vodovotz
Shock (Augusta, Ga.) 29 (1), 104, 2008
742008
Mathematical simulation of the innate immune response
G Clermont, CC Chow, R Kumar, Y Vodovotz
CRITICAL CARE MEDICINE 29 (12), A111-A111, 2001
82001
Mathematical simulations of sepsis and trauma
Y Vodovotz, C Chow, J Bartels, C Lagoa, R Kumar, J Day, J Rubin, ...
Proceedings of the 11th Congress of the European Shock Society, 2005
72005
Beyond the single average tumor: Understanding IO Combinations using a clinical QSP model that incorporates heterogeneity in patient response
R Kumar, K Thiagarajan, L Jagannathan, L Liu, K Mayawala, D de Alwis, ...
CPT: Pharmacometrics & Systems Pharmacology, 2021
42021
Mathematical models predict the course of the inflammatory response in rats subjected to trauma-hemorrhagic shock and to anti–tumor necrosis factor α therapy in endotoxemia
CE Lagoa, C Chow, J Bartels, A Barrat, R Kumar, J Day, J Rubin, ...
Journal of Critical Care 4 (20), 393-394, 2005
42005
Prediction of the acute inflammatory response from a mathematical model
CE Lagoa, G Clermont, R Kumar, J Bartels, CC Chow, Y Vodovotz
CHEST Journal 124 (4_MeetingAbstracts), 121S-a-121S, 2003
32003
A theoretical model for the simulation of sepsis
R Kumar, CC Chow, G Clermont, Y Vodovotz
JOURNAL OF LEUKOCYTE BIOLOGY, 90-90, 2001
32001
Use of a large biological model with single-dose clinical data to predict hemoglobin (Hb) response in patients with anemia
K Moore, R Kumar, J Zhang, V Hurez, S Kellermann, C Erickson-Miller, ...
American Conference on Pharmacometrics, 3-6.2011, 2011
22011
Inter-tumoral heterogeneity of progressive disease in melanoma patients treated with pembrolizumab.
B Topp, R Kumar, K Mayawala, D de Alwis, MD Hellmann, A Snyder
CANCER RESEARCH 80 (21), 2020
12020
Designing Optimal Basal Insulin Analogs Using a Quantitative Systems Pharmacology Model
R Kumar, J Geiser, J Leohr, D Leishman, B Topp
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 41, S20-S20, 2014
12014
Predicting the response to therapy from a mathematical model
G Clermont, R Kumar, J Bartels, Y Vodovotz, S Chang, C Chow
Critical Care 8 (1), 1-2, 2004
12004
Abstract PO-131: Inter-tumoral heterogeneity of progressive disease in melanoma patients treated with pembrolizumab
B Topp, R Kumar, K Mayawala, D de Alwis, MD Hellmann, A Snyder
Cancer Research 80 (21 Supplement), PO-131-PO-131, 2020
2020
Development of a quantitative systems pharmacology model for prediction of mineralcorticoid receptor antagonists-induced hyperkalemia
T Nakada, M Rengaswamy, K Dasika, R Kumar, R Saito
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 44, S116-S116, 2017
2017
Leveraging a Quantitative Systems Pharmacology Model to Explore the Mechanism of Action of a Novel Basal Insulin Analog
P Garhyan, R Kumar, J Geiser
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 43, S74-S74, 2016
2016
An open-source platform for Sensitivity Analysis of QSP models
P Packirisamy, K Dasika, R Kumar
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 43, S113-S113, 2016
2016
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Articles 1–20