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Ivo Buchhalter
Ivo Buchhalter
Omics IT and Data Management Core Facility, German Cancer Research Center (DKFZ)
Bestätigte E-Mail-Adresse bei dkfz.de
Titel
Zitiert von
Zitiert von
Jahr
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
9372020
The landscape of genomic alterations across childhood cancers
SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ...
Nature 555 (7696), 321-327, 2018
8682018
The whole-genome landscape of medulloblastoma subtypes
PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ...
Nature 547 (7663), 311-317, 2017
6902017
New brain tumor entities emerge from molecular classification of CNS-PNETs
D Sturm, BA Orr, UH Toprak, V Hovestadt, DTW Jones, D Capper, M Sill, ...
Cell 164 (5), 1060-1072, 2016
6272016
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
PA Northcott, C Lee, T Zichner, AM Stütz, S Erkek, D Kawauchi, DJH Shih, ...
Nature 511 (7510), 428-434, 2014
5392014
Atypical teratoid/rhabdoid tumors are comprised of three epigenetic subgroups with distinct enhancer landscapes
PD Johann, S Erkek, M Zapatka, K Kerl, I Buchhalter, V Hovestadt, ...
Cancer cell 29 (3), 379-393, 2016
4132016
Active medulloblastoma enhancers reveal subgroup-specific cellular origins
CY Lin, S Erkek, Y Tong, L Yin, AJ Federation, M Zapatka, P Haldipur, ...
Nature 530 (7588), 57-62, 2016
3252016
A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing
TS Alioto, I Buchhalter, S Derdak, B Hutter, MD Eldridge, E Hovig, ...
Nature communications 6 (1), 1-13, 2015
2772015
Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort
SM Waszak, PA Northcott, I Buchhalter, GW Robinson, C Sutter, ...
The Lancet Oncology 19 (6), 785-798, 2018
2572018
Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets
F Sahm, D Schrimpf, DTW Jones, J Meyer, A Kratz, D Reuss, D Capper, ...
Acta neuropathologica 131 (6), 903-910, 2016
1932016
The mutational pattern of primary lymphoma of the central nervous system determined by whole-exome sequencing
I Vater, M Montesinos-Rongen, M Schlesner, A Haake, F Purschke, ...
Leukemia 29 (3), 677-685, 2015
1912015
Recurrent MET fusion genes represent a drug target in pediatric glioblastoma
Nature medicine 22 (11), 1314-1320, 2016
1522016
Risk-adapted therapy for young children with medulloblastoma (SJYC07): therapeutic and molecular outcomes from a multicentre, phase 2 trial
GW Robinson, VA Rudneva, I Buchhalter, CA Billups, SM Waszak, ...
The Lancet Oncology 19 (6), 768-784, 2018
1492018
Pan-cancer analysis of whole genomes.
S Hirano, L Yang, M Juul, CA Purdie, BP O'Neill, R Kabbe, ...
Nature 578 (DKFZ-2020-01051), 82-93, 2020
1422020
Size matters: dissecting key parameters for panel‐based tumor mutational burden analysis
I Buchhalter, E Rempel, V Endris, M Allgäuer, O Neumann, AL Volckmar, ...
International journal of cancer 144 (4), 848-858, 2019
1182019
EML4‐ALK fusion variant V3 is a high‐risk feature conferring accelerated metastatic spread, early treatment failure and worse overall survival in ALK+ non‐small …
P Christopoulos, V Endris, F Bozorgmehr, M Elsayed, M Kirchner, J Ristau, ...
International Journal of Cancer 142 (12), 2589-2598, 2018
942018
Measurement of tumor mutational burden (TMB) in routine molecular diagnostics: in silico and real‐life analysis of three larger gene panels
V Endris, I Buchhalter, M Allgäuer, E Rempel, A Lier, AL Volckmar, ...
International journal of cancer 144 (9), 2303-2312, 2019
892019
The molecular landscape of ETMR at diagnosis and relapse
S Lambo, SN Gröbner, T Rausch, SM Waszak, C Schmidt, A Gorthi, ...
Nature 576 (7786), 274-280, 2019
782019
Germline elongator mutations in sonic hedgehog medulloblastoma
SM Waszak, GW Robinson, BL Gudenas, KS Smith, A Forget, M Kojic, ...
Nature 580 (7803), 396-401, 2020
712020
Combined targeted DNA and RNA sequencing of advanced NSCLC in routine molecular diagnostics: analysis of the first 3,000 Heidelberg cases
AL Volckmar, J Leichsenring, M Kirchner, P Christopoulos, O Neumann, ...
International Journal of Cancer 145 (3), 649-661, 2019
692019
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