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David G. Leach, Ph.D.
David G. Leach, Ph.D.
Research Scientist at Chevron Corporation
Verified email at alumni.rice.edu
Title
Cited by
Cited by
Year
STINGel: Controlled release of a cyclic dinucleotide for enhanced cancer immunotherapy
DG Leach, N Dharmaraj, SL Piotrowski, TL Lopez-Silva, YL Lei, ...
Biomaterials 163, 67-75, 2018
1822018
Sequence-specific, nanomolar peptide binding via cucurbit [8] uril-induced folding and inclusion of neighboring side chains
LC Smith, DG Leach, BE Blaylock, OA Ali, AR Urbach
Journal of the American Chemical Society 137 (10), 3663-3669, 2015
1702015
Advances in immunotherapy delivery from implantable and injectable biomaterials
DG Leach, S Young, JD Hartgerink
Acta biomaterialia 88, 15-31, 2019
1482019
Multidomain peptide hydrogel accelerates healing of full-thickness wounds in diabetic mice
NC Carrejo, AN Moore, TL Lopez Silva, DG Leach, IC Li, DR Walker, ...
ACS biomaterials science & engineering 4 (4), 1386-1396, 2018
1082018
Chemical functionality of multidomain peptide hydrogels governs early host immune response
TL Lopez-Silva, DG Leach, A Azares, IC Li, DG Woodside, JD Hartgerink
Biomaterials 231, 119667, 2020
982020
Influence of injection technique, drug formulation and tumor microenvironment on intratumoral immunotherapy delivery and efficacy
NM Muñoz, M Williams, K Dixon, C Dupuis, A McWatters, R Avritscher, ...
Journal for immunotherapy of cancer 9 (2), 2021
772021
Self-assembling multidomain peptides: design and characterization of neutral peptide-based materials with pH and ionic strength independent self-assembly
TL Lopez-Silva, DG Leach, IC Li, X Wang, JD Hartgerink
ACS biomaterials science & engineering 5 (2), 977-985, 2018
482018
Biomaterial-facilitated immunotherapy for established oral cancers
DG Leach, N Dharmaraj, TL Lopez-Silva, JR Venzor, BH Pogostin, ...
ACS biomaterials science & engineering 7 (2), 415-421, 2021
292021
Drug-mimicking nanofibrous peptide hydrogel for inhibition of inducible nitric oxide synthase
DG Leach, JM Newton, MA Florez, TL Lopez-Silva, AA Jones, S Young, ...
ACS biomaterials science & engineering 5 (12), 6755-6765, 2019
212019
Local anti–PD-1 delivery prevents progression of premalignant lesions in a 4NQO-oral carcinogenesis mouse model
Y Shi, T Xie, DG Leach, B Wang, S Young, AA Osman, AG Sikora, X Ren, ...
Cancer Prevention Research 14 (8), 767-778, 2021
152021
Rock-Fluid Interaction and Its Application in Unconventional Production
W Wang, W Wei, D Leach, C Yan, K Spilker
SPE/AAPG/SEG Unconventional Resources Technology Conference 2020, 2020
82020
Molecular deep dive into oilfield microbiologically influenced corrosion: A detailed case study of MIC failure analysis in an unconventional asset
DG Leach, W Wang, C Yan, D Mattis, R MacLeod, W Wei
AMPP CORROSION, D031S027R002, 2022
12022
Stimulator of Interferon Genes Pathway Activation through the Controlled Release of STINGel Mediates Analgesia and Anti-Cancer Effects in Oral Squamous Cell Carcinoma
MP Dong, N Dharmaraj, E Kaminagakura, J Xue, DG Leach, ...
Biomedicines 12 (4), 920, 2024
2024
Enhancing water chemistry for improved well performance
W Wang, W Wei, Y Tang, JC Visser, DG Leach, H Lu, SKK Lattimer
US Patent App. 18/319,884, 2023
2023
Chemical Control of H2S for Unconventional Production: Performance Evaluation of Triazine and Non-Triazine H2S Scavengers in Challenging Environments
D Leach, C Yan, W Wang, W Wei
SPE International Conference on Oilfield Chemistry?, D021S008R001, 2023
2023
Impact of subsurface fluid chemistry on microbial growth, corrosion, and reservoir souring in unconventional assets
DG Leach, W Wang, C Yan, R MacLeod, D Mattis, W Wei
Unconventional Resources Technology Conference, 20–22 June 2022, 1676-1695, 2022
2022
Neutral multidomain peptide hydrogels and uses thereof
J Hartgerink, D Leach, T Lopez-silva
US Patent App. 17/285,767, 2021
2021
Synthetic multidomain peptide biomaterials that inhibit inducible nitric oxide synthase
J Hartgerink, AG Sikora, D Leach, JM Newton, S Young
US Patent App. 17/127,512, 2021
2021
Hydrogel delivery of sting immunotherapy for treatment cancer
S Young, D Leach, JD Hartgerink
US Patent App. 16/618,043, 2020
2020
Abstract No. 430 Self-assembling hydrogel platform improves intratumoral drug delivery and retention
D Leach, N Muñoz, C Dupuis, M Williams, K Dixon, S Young, R Sheth, ...
Journal of Vascular and Interventional Radiology 31 (3), S192, 2020
2020
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