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Ryan Adam
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Restoring cystic fibrosis transmembrane conductance regulator function reduces airway bacteria and inflammation in people with cystic fibrosis and chronic lung infections
KB Hisert, SL Heltshe, C Pope, P Jorth, X Wu, RM Edwards, M Radey, ...
American journal of respiratory and critical care medicine 195 (12), 1617-1628, 2017
3242017
Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs
DA Stoltz, T Rokhlina, SE Ernst, AA Pezzulo, LS Ostedgaard, PH Karp, ...
The Journal of clinical investigation 123 (6), 2685-2693, 2013
1452013
Assessing mucociliary transport of single particles in vivo shows variable speed and preference for the ventral trachea in newborn pigs
MJ Hoegger, M Awadalla, E Namati, OA Itani, AJ Fischer, AJ Tucker, ...
Proceedings of the National Academy of Sciences 111 (6), 2355-2360, 2014
802014
Air trapping and airflow obstruction in newborn cystic fibrosis piglets
RJ Adam, AS Michalski, C Bauer, MH Abou Alaiwa, TJ Gross, ...
American journal of respiratory and critical care medicine 188 (12), 1434-1441, 2013
752013
Tracheomalacia is associated with lower FEV1 and Pseudomonas acquisition in children with CF
AJ Fischer, SB Singh, RJ Adam, DA Stoltz, CF Baranano, S Kao, ...
Pediatric pulmonology 49 (10), 960-970, 2014
592014
Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs
DK Meyerholz, DA Stoltz, ND Gansemer, SE Ernst, DP Cook, MD Strub, ...
Laboratory investigation 98 (6), 825-838, 2018
422018
Acute administration of ivacaftor to people with cystic fibrosis and a G551D-CFTR mutation reveals smooth muscle abnormalities
RJ Adam, KB Hisert, JD Dodd, B Grogan, JL Launspach, JK Barnes, ...
JCI insight 1 (4), 2016
412016
Early airway structural changes in cystic fibrosis pigs as a determinant of particle distribution and deposition
M Awadalla, S Miyawaki, MH Abou Alaiwa, RJ Adam, DC Bouzek, ...
Annals of biomedical engineering 42, 915-927, 2014
312014
Restoring CFTR function reduces airway bacteria and inflammation in people with cystic fibrosis and chronic lung infections
KB Hisert, SL Heltshe, C Pope, P Jorth, X Wu, RM Edwards, M Radey, ...
Am J Respir Crit Care Med 195 (12), 1617-1628, 2017
292017
Integrin α6β4 identifies human distal lung epithelial progenitor cells with potential as a cell-based therapy for cystic fibrosis lung disease
X Li, N Rossen, PL Sinn, AL Hornick, BR Steines, PH Karp, SE Ernst, ...
PloS one 8 (12), e83624, 2013
292013
Acid-sensing ion channel 1a contributes to airway hyperreactivity in mice
LR Reznikov, DK Meyerholz, RJ Adam, M Abou Alaiwa, O Jaffer, ...
PLoS One 11 (11), e0166089, 2016
262016
Sonographic evidence of abnormal tracheal cartilage ring structure in cystic fibrosis
A Diwakar, RJ Adam, AS Michalski, MM Tamegnon, AJ Fischer, ...
The Laryngoscope 125 (10), 2398-2404, 2015
232015
Comparison of the surgical resection and infarct 5/6 nephrectomy rat models of chronic kidney disease
RJ Adam, AC Williams, AJ Kriegel
American Journal of Physiology-Renal Physiology 322 (6), F639-F654, 2022
152022
Computer-aided analysis of airway trees in micro-CT scans of ex vivo porcine lung tissue
C Bauer, R Adam, DA Stoltz, RR Beichel
Computerized medical imaging and graphics 36 (8), 601-609, 2012
132012
CF airway smooth muscle transcriptome reveals a role for PYK2
DP Cook, RJ Adam, K Zarei, B Deonovic, MR Stroik, ND Gansemer, ...
JCI insight 2 (17), 2017
122017
Early lung disease exhibits bacteria-dependent and-independent abnormalities in cystic fibrosis pigs
DC Bouzek, MH Abou Alaiwa, RJ Adam, AA Pezzulo, LR Reznikov, ...
American journal of respiratory and critical care medicine 204 (6), 692-702, 2021
112021
Sympathoexcitation in response to cardiac and pulmonary afferent stimulation of TRPA1 channels is attenuated in rats with chronic heart failure
RJ Adam, Z Xia, K Pravoverov, J Hong, AJ Case, HD Schultz, SJ Lisco, ...
American Journal of Physiology-Heart and Circulatory Physiology 316 (4 …, 2019
102019
Cystic fibrosis transmembrane conductance regulator potentiation as a therapeutic strategy for pulmonary edema: a proof-of-concept study in pigs
X Li, LGV Buonfiglio, RJ Adam, DA Stoltz, J Zabner, AP Comellas
Critical care medicine 45 (12), e1240-e1246, 2017
92017
Macrophage activation in stellate ganglia contributes to lung injury‐induced arrhythmogenesis in male rats
J Hong, RJ Adam, L Gao, T Hahka, Z Xia, D Wang, TA Nicholas, IH Zucker, ...
Acta physiologica 232 (2), e13657, 2021
62021
Postnatal airway growth in cystic fibrosis piglets
RJ Adam, MH Abou Alaiwa, DC Bouzek, DP Cook, ND Gansemer, PJ Taft, ...
Journal of Applied Physiology 123 (3), 526-533, 2017
62017
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