Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 5406 | 2018 |
RIP3 mediates the embryonic lethality of caspase-8-deficient mice WJ Kaiser, JW Upton, AB Long, D Livingston-Rosanoff, LP Daley-Bauer, ... Nature 471 (7338), 368-372, 2011 | 1074 | 2011 |
Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL WJ Kaiser, H Sridharan, C Huang, P Mandal, JW Upton, PJ Gough, ... Journal of Biological Chemistry 288 (43), 31268-31279, 2013 | 925 | 2013 |
DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA JW Upton, WJ Kaiser, ES Mocarski Cell host & microbe 11 (3), 290-297, 2012 | 768 | 2012 |
Virus inhibition of RIP3-dependent necrosis JW Upton, WJ Kaiser, ES Mocarski Cell host & microbe 7 (4), 302-313, 2010 | 640 | 2010 |
RIP3 induces apoptosis independent of pronecrotic kinase activity P Mandal, SB Berger, S Pillay, K Moriwaki, C Huang, H Guo, JD Lich, ... Molecular cell 56 (4), 481-495, 2014 | 571 | 2014 |
Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif WJ Kaiser, MK Offermann The Journal of Immunology 174 (8), 4942-4952, 2005 | 423 | 2005 |
Cutting Edge: RIP1 kinase activity is dispensable for normal development but is a key regulator of inflammation in SHARPIN-deficient mice SB Berger, V Kasparcova, S Hoffman, B Swift, L Dare, M Schaeffer, ... The Journal of Immunology 192 (12), 5476-5480, 2014 | 385 | 2014 |
Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways ES Mocarski, JW Upton, WJ Kaiser Nature Reviews Immunology 12 (2), 79-88, 2012 | 355 | 2012 |
RIPK3 activates parallel pathways of MLKL-driven necroptosis and FADD-mediated apoptosis to protect against influenza A virus S Nogusa, RJ Thapa, CP Dillon, S Liedmann, TH Oguin, JP Ingram, ... Cell host & microbe 20 (1), 13-24, 2016 | 344 | 2016 |
Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-8 in an RIP3-independent manner L Bossaller, PI Chiang, C Schmidt-Lauber, S Ganesan, WJ Kaiser, ... The Journal of Immunology 189 (12), 5508-5512, 2012 | 331 | 2012 |
Receptor-interacting protein homotypic interaction motif-dependent control of NF-κB activation via the DNA-dependent activator of IFN regulatory factors WJ Kaiser, JW Upton, ES Mocarski The Journal of Immunology 181 (9), 6427-6434, 2008 | 317 | 2008 |
Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death D Weng, R Marty-Roix, S Ganesan, MK Proulx, GI Vladimer, WJ Kaiser, ... Proceedings of the National Academy of Sciences 111 (20), 7391-7396, 2014 | 315 | 2014 |
RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition WJ Kaiser, LP Daley-Bauer, RJ Thapa, P Mandal, SB Berger, C Huang, ... Proceedings of the National Academy of Sciences 111 (21), 7753-7758, 2014 | 305 | 2014 |
Herpes simplex virus suppresses necroptosis in human cells H Guo, S Omoto, PA Harris, JN Finger, J Bertin, PJ Gough, WJ Kaiser, ... Cell host & microbe 17 (2), 243-251, 2015 | 268 | 2015 |
Inhibitor of Apoptosis Proteins Physically Interact with and Block Apoptosis Induced by Drosophila Proteins HID and GRIM D Vucic, WJ Kaiser, LK Miller Molecular and cellular biology 18 (6), 3300-3309, 1998 | 268 | 1998 |
Inhibition of reaper-induced apoptosis by interaction with inhibitor of apoptosis proteins (IAPs) D Vucic, WJ Kaiser, AJ Harvey, LK Miller Proceedings of the National Academy of Sciences 94 (19), 10183-10188, 1997 | 262 | 1997 |
TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice JA Rickard, H Anderton, N Etemadi, U Nachbur, M Darding, N Peltzer, ... Elife 3, e03464, 2014 | 255 | 2014 |
Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3 S Kang, T Fernandes-Alnemri, C Rogers, L Mayes, Y Wang, C Dillon, ... Nature communications 6 (1), 7515, 2015 | 246 | 2015 |
Divergent host responses during primary simian immunodeficiency virus SIVsm infection of natural sooty mangabey and nonnatural rhesus macaque hosts G Silvestri, A Fedanov, S Germon, N Kozyr, WJ Kaiser, DA Garber, ... Journal of virology 79 (7), 4043-4054, 2005 | 241 | 2005 |